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All published articles 889

Evaluation of Omega-3, Omega-6 and Lipid Contents of Wistar Rats Treated with Frequently Used Cooking Oil in Nigeria

Osughe Wisdom Olume, Ibitoroko Maureen George-Opuda & Brown Holy · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Many studies suggest a connection between the consumption of vegetable oils and cardiovascular diseases (CVD). This research investigated the effects of various cooking oils on the lipid profiles of Wistar rats. The study involved forty-two Wistar rats, approximately 3 months old...

Open access Research Article 10.9734/jamps/2025/v27i7795

Knowledge, Practices, and Safety Awareness Regarding Household Chemicals among Saudi Families in Makkah Province: A Cross-sectional Survey

Liale Y. Oukal, Mohamed A. El-Moselhy, Elsamoual Ibrahim Ahmedani & Bashir A. Yousef · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Background: Household chemical products are widely used for hygiene and cleaning, but their improper use and low awareness level can lead to severe health and safety problems. The current study was carried out to assess knowledge and practice regarding household chemical safety a...

Open access Research Article 10.9734/jamps/2025/v27i6793

Assessing Non-Alcoholic Fatty Liver Disease and Associated Liver Enzyme Levels in Persons with Type II Diabetes Mellitus

Kiyesi A, Ogamba M I, Owamagbe E M, Meka I A & Amadi B C · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Background: This study aims to assess the prevalence of Non-Alcoholic Fatty Liver Disease (NAFLD) among individuals with diabetes and identify the associated factors that contribute to its development. By investigating this relationship, we hope to gain valuable insights into the...

Open access Research Article 10.9734/jamps/2025/v27i7794

Physical and Neurobehavioural Effects of Mentha piperita Ethanolic Leaf Extract on Mercury Intoxicated Wistar Rats

D. K Ogbuokiri & A.L Asomugha · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Mercury is a persistent environmental toxicant with significant neurotoxic effects, posing serious health risks due to its bioaccumulation and toxicity in various forms—elemental, inorganic, and organic. This study reviews mercury’s toxicological profiles, exposure pathways, and...

Open access Research Article 10.9734/jamps/2025/v27i6792

Hepatoprotective Effects of Monoon longifolium (False Ashoka) Seed Extract against Lead Acetate–Induced Liver Damage in Adult Female Wistar Rats

Uzozie Chikere Ofoego, Onuorah Ifechukwu Paschaline, Mbah Chikodili Adolphus & John Obinna Chukwudike · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

The seed of Monoon longifolium is known to possess antioxidant and hepatoprotective properties. This study investigated the protective effects of its methanolic seed extract (MLSE) against lead acetate-induced liver damage in adult female Wistar rats. Thirty-six rats were randoml...

Open access Research Article 10.9734/jamps/2025/v27i6791

Antimicrobial Activity of Ficus vogelii Miq and Boerhaavia diffusa Linn against Multidrug-Resistant Respiratory Pathogens with Bactericidal Kinetics and Cytotoxicity

Morenike E. Coker & Esther O. Adebayo · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Introduction: Respiratory tract infections (RTIs) are some of the most common and significant health-related issues seen in clinical medicine. Many studies have shown that comorbid illnesses are associated with acute respiratory tract infections. The effectiveness of available an...

Open access Research Article 10.9734/jamps/2025/v27i6790

Gastric Cancer Burden in Northern Nigeria: A Retrospective Study of 10-Years

Gbaa LZ, Ojo BA, Eke BA, Anenga RN, Umobong EO, Unande, Pededoo, Inienger, Ikwulono JO & Obunadike CB · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Gastric cancer is a major contributor to global cancer mortality. In Nigeria, especially in the North Central regions such as Makurdi, data on its prevalence and pathological features remain limited. To describe the demographic and histopathologic profile of gastric cancer cases...

Open access Research Article 10.9734/jamps/2025/v27i6789

Artificial Intelligence in Medical Research: Ethical and Regulatory Challenges in Developing Economies

Charles Ntungwen Fokunang, Marceline Djuidje Ngounoue, Joseph Fokam, Estella Achick Tembe-Fokunang, Basile Ngono, Innocente Mantsana, Mfochive Njindam Illiasou, Christie Tiwoda, Francis Ndongo Ateba, Tchinda Tiabou, Lowe Gnintedem Patrick Juvet, Pasteur Sap Jacques Duclaire, Mgr Etoundi Jean, Mpah Wanga Julien Eymard, Ngu Paul Nembo, Jerome Ateudjio, Charles Kouanfack, Eboumbou Moukoko Caroline Else, Leopold Lehman, Binan Fidele Ange, Lovet Benyella Fokunang, Atanga Benjamin, Zoung-Khanyi Bisseck Anne Cécile, Marie Claire Assoumou Okomo, Dickson Shey Nsagha, Mbacham Fon Wilfred, Marie Therese Obama Abena Ondoua, Zintchem Roger & Vincent Pryde Kehdingha Titanji · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Introduction: Clinical research is a key area in which the use of AI in healthcare data seen a significant increase, even though met with great ethical, legal and regulatory challenges. Artificial Intelligence (AI) concerns the ability of algorithms encoded in technology to learn...

Open access Research Article 10.9734/jamps/2025/v27i6788

Protein Corona Formation on Surface-modified SPIO Nanoparticles: Effects of pH, Coating and Incubation Time

Abdulrahman Ahmed Mahmood, Ahmed Abdullah Omar, Ali Mohammed Salih, Mohammed Jamal Ahmed, Sadat Abdulla Aziz & Mardin Mohammed Obaid · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Aims: The goal of this review is to look into how the protein corona forms and affects superparamagnetic iron oxide nanoparticles (SPIO NPs). It will focus on how changes to the surface, pH levels, and incubation time affect their biological identity and biomedical performance. S...

Open access Research Article 10.9734/jamps/2025/v27i6787

Pathological and Psychosocial Consequences of Sexual Violence Amongst Young and Adolescent Girls in the Kumba Health District, Southwest Region, Cameroon

Judith Lum Ndamukong-Nyanga & FOJE CARLSON KIBOT · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Sexual violence is a serious public health and human rights problem with both short- and long-term consequences on women's physical, mental, sexual and reproductive health. The main aim of this study was to outline the pathological and psychosocial consequences and its preventive...

Open access Research Article 10.9734/jamps/2025/v27i6786

Association of Uterine Fibroids with Various Age Related Parameters Among Premenopausal Women: A Prospective Analytical Study in a Tertiary Health Care Center

Samuel I. Udobi, Onuh A. C, Udobi J.I & Ezebialu I. U. · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Background: Uterine fibroid is the commonest gynaeclogical tumor and is responsible for much of the morbidity among women. It’s poor management can lead to mortality. Parity and various age parameters (age at menarche, actual age and menstrual age) have been postulated to have in...

Open access Research Article 10.9734/jamps/2025/v27i6785

Identification of Novel Polyketide Synthase 13 of Mycobacterium Tuberculosis Inhibitors: A Modelling Approach Using the Pharmacophore Method -Based Virtual Screening

Djako Akassa Marius Bernard, Niaré Adama, Fofana Issouf, Moussé Logbo Mathias, Kéita Mélalie & Megnassan Eugène · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis. It remains a major public health problem worldwide. In 2022, 10.6 million people contracted tuberculosis and 1.3 million died from it.  This manuscript presents our work, the aim of which is to find new i...

Open access Research Article 10.9734/jamps/2025/v27i6784

Innovative Superdisintegrant Strategy for the Formulation of Rapidly Disintegrating Lamotrigine Tablets

Ramakrishnasai N, Sharath T P, Narahari K V, Naga mownica K P, Lakshmi Priya N S, Shrikrishna M Naik & Sagar M · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Aims: Lamotrigine (LMG) is a poorly water-soluble antiepileptic drug (0.17 mg/mL at 25°C), commonly prescribed for epilepsy, including secondary generalized tonic-clonic seizures, as well as simple and complex partial seizures. Due to its low solubility and swallowing difficulty...

Open access Research Article 10.9734/jamps/2025/v27i5783

School Health Program: Early Detection and Environmental Health Assessment of Children and Adolescents in National Guard Iskan, Alhassa

Abdulrahman Alarfaj, Mounther AlNaim, Ahmed Alhashim, Mohamed Al-Falah, Abdulaziz Alyousof, Saleh Almulhim, Munerah Alhumaidy & Ibrahim Albakheet · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Background: The health and well-being of school students are critical for future generations. In Saudi Arabia, the School Health Program aims to enhance student health through early detection of health issues and evaluation of school environments. This study assessed the general...

Open access Research Article 10.9734/jamps/2025/v27i5782

Evaluation of a Cell-Based Anti-Mosquito Vaccine Derived from Malpighian Tubules of Culex Mosquitoes in a Mouse Model

Mst. Sakila Jahan, Sharmin Mustari, Md. Naymur Rahman, Sadia Islam Reya, Moni Krishno Mohanta, Md. Ariful Hasan & Md Fazlul Haque · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Mosquitoes are vectors for several deadly diseases such as dengue, malaria, filariasis, yellow fever, and Zika, contributing significantly to global mortality. Current control methods such as physical, chemical, and biological control are costly, often ineffective, and can pose r...

Open access Research Article 10.9734/jamps/2025/v27i5780