Infective endocarditis is a potentially life-threatening infection that may cause severe valvular and perivalvular complications, particularly when microbiological confirmation is not obtained. This case report describes a 42-year-old man who presented with progressive dyspnoea f...
Open access
Research Article10.9734/jpri/2026/v38i107877
Aims: To characterise the distributions and pairwise associations among C-class solar-flare magnitude, duration, ion temperature (Ti), electron temperature (Te), total electron content (TEC), solar zenith angle (SZA), sunspot number (SSN), and 10.7 cm solar radio flux (F10.7) in...
Open access
Research Article10.9734/iaarj/2026/v8i1129
For the quantitative determination of Tafamidis in bulk and pharmaceutical dosage forms, a straightforward, accurate, precise, and environmentally friendly reverse-phase high-performance liquid chromatographic (RP-HPLC) method was developed and validated. To achieve optimal chrom...
Open access
Research Article10.9734/jpri/2026/v38i107876
Aims: This study aimed to fabricate copper oxide nanoparticles (CuO NPs) using aqueous ginger (Zingiber officinale) rhizome extract as a reducing and stabilising agent and to evaluate their antibacterial activity against selected clinical bacterial isolates. Methodology: The fabr...
Open access
Research Article10.9734/jpri/2026/v38i97873
Background: Despite substantial progress in the management of drug-resistant tuberculosis (DR-TB) through the introduction of all-oral treatment regimens, unfavourable treatment outcomes remain a major challenge in high-burden settings. Beyond patient and clinical characteristics...
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Research Article10.9734/jpri/2026/v38i97875
Olbers’ paradox is a useful convergence test for cosmological radiation fields because an infinite, homogeneous, eternal and static population of identical luminous sources produces a divergent bolometric flux in Euclidean space. This analytical study compares that classical resu...
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Research Article10.9734/iaarj/2026/v8i1128
The root of Panax ginseng C. A. Meyer and its dammarane-type saponins, the ginsenosides, occupy an unusual position in contemporary pharmaceutical science. Few plant-derived substances have attracted a comparable volume of mechanistic investigation, yet few have produced so modes...
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Research Article10.9734/jpri/2026/v38i97872
Background: COVID-19 frequently impairs pulmonary function during the post-recovery phase. Assessing respiratory status using accessible, equipment-free methods such as Single Breath Count (SBC) and Peak Expiratory Flow Rate (PEFR) is valuable for monitoring long-term functional...
Open access
Research Article10.9734/jpri/2026/v38i97871
Diabetes mellitus is a chronic metabolic disorder characterised by persistent hyperglycaemia and complications that may affect multiple organ systems. This study used a computational approach to compare selected nutraceutical compounds with FDA-approved antidiabetic drugs for the...
Open access
Research Article10.9734/jpri/2026/v38i97870
A stability-indicating reverse-phase high-performance liquid chromatographic (RP-HPLC) method was developed and validated for the quantitative estimation of Tafamidis in bulk drug and pharmaceutical dosage forms. Chromatographic separation was achieved using a Phenomenex Gemini O...
Open access
Research Article10.9734/jpri/2026/v38i97869
Background: Necrotising fasciitis (NF) is an uncommon, fulminant infection of the superficial fascia and subcutaneous tissue that carries considerable morbidity and mortality when recognition or intervention is delayed. Primary involvement of the breast is exceptionally rare, and...
Open access
Research Article10.9734/jpri/2026/v38i87866
Aims: To synthesize (Z)-7-nitro-1-phenyl-3-((2-((1-phenylethylidene)amino)ethyl)amino)quinoxalin-2(1H)-one derivatives and evaluate their possible biological properties. Methods: The substituted (Z)-7-nitro-1-phenyl-3-((2-((1-phenylethylidene)amino)ethyl)amino)quinoxalin-2(1H)-o...
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Research Article10.9734/jpri/2026/v38i97867
Aims: Oral diseases are associated with complex microbial biofilms and oxidative inflammatory processes. This study evaluated the phytochemical profile, total phenolic content, DPPH radical-scavenging activity, and preliminary antimicrobial activity of aqueous and hydroethanolic...
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Research Article10.9734/jpri/2026/v38i97868
Antibiotic resistance has increased the need to investigate new antibacterial scaffolds. This study synthesized a series of quinoxaline sulfonamide Schiff base derivatives, designated 1a–h, and evaluated their antibacterial activity against selected bacterial strains. The compou...
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Research Article10.9734/jpri/2026/v38i87865
The treatment of 4-Amino-N-(5-methylisoxazol-3-yl)benzenesulfonamide (1) with substituted aromatic aldehydes and ketones in absolute ethanol with 2-3 drops of glacial acetic acid as a catalyst under reflux conditions afforded Schiff bases of sulfonamide derivatives (1a-1f) with y...
Open access
Research Article10.9734/jpri/2026/v38i87864