Introduction: Migraine is a chronic neurological disorder with recurrent headaches and aura, shaped by both environmental and genetic factors. In Saudi Arabia, rising prevalence contrasts with scarce genetic research. This study systematically reviews local evidence on migraine-r...
Open access
Research Article10.9734/jpri/2025/v37i97743
Sarabjot Singh-Sethi-Makkar, Parinita Aroori, Leela Sarmada Gaddamanugu, Siddharth Thokale, Krishna Moparthi, Kyaw Hein & Sanjana Palakodeti·Journal of Pharmaceutical Research International·2025
Background: Migraines are a common neurological disorder which are characterised by recurrent headaches accompanied by ‘auras’, nausea, vomiting and photophobia. Objective: This review summarises the role of Calcitonin gene-related peptide (CGRP) in migraine as a therapeutic and...
Open access
Research Article10.9734/jpri/2025/v37i97742
Chia (Salvia hispanica L.) is an emerging oilseed crop renowned for its rich nutritional profile and diverse health-promoting properties. Black chia seed oil (BCO) is particularly valued for its high content of omega-3 fatty acids and bioactive compounds, making it a promising fu...
Open access
Research Article10.9734/jpri/2025/v37i97740
Tapinanthus globiferus, a hemiparasitic mistletoe extensively used in African ethnomedicine, was evaluated for its redox-modulatory and cytotoxic properties using Drosophila melanogaster under non-stressed physiological conditions. Methanolic crude extract and solvent-partitioned...
Open access
Research Article10.9734/jpri/2025/v37i97739
Aims: The propagation of light in vacuo has generally been assumed to be isotropic; i.e., its recessional velocity is assumed to be identical with its return speed back to the observer. This article presents a novel conceptual approach to this fundamental yet unresolved issue in...
Open access
Research Article10.9734/iaarj/2025/v7i1118
The Siddha system of medicine, deeply rooted in Tamil Nadu's traditional practices, emphasizes holistic health through herbal and mineral formulations. Combining antibacterial activity, molecular docking mechanisms, and toxicological safety assessments, this work offers a thorou...
Open access
Research Article10.9734/jpri/2025/v37i97738
Aims: We evaluated kerosene as a potential substitute, assessing its clearing efficiency, impact on tissue morphology, staining quality, and diagnostic accuracy. Study Design: A prospective comparative study. Place and Duration of Study: The Cross-sectional research was conducte...
Open access
Research Article10.9734/jpri/2025/v37i87737
SAWADOGO Paténéma, SAWADOGO Touwindséda Aimée, KOUSSOUBE Ignace, TRAORE Kadiatou Tata, DA Filkpièrè Léonard, Tindano Basile, Ouédraogo Noufou, Bayala Balé, OUEDRAOGO Youssoufou & BELEMTOUGRI Gourounga Raymond·Journal of Pharmaceutical Research International·2025
Vernonia colorata leaves are traditionally used in Africa to treat various diseases, including inflammation. This study aimed to evaluate the anti-inflammatory effects of the aqueous extract of Vernonia colorata leaves (AEVC) on both acute and subacute inflammation models. Induce...
Open access
Research Article10.9734/jpri/2025/v37i87736
Background: PAH emission features in a single observation, allowing for a robust and systematic study of their relative variations without the systematic uncertainties inherent in stitching together data from different instruments or observing modes. This provides a powerful and...
Open access
Research Article10.9734/iaarj/2025/v7i1117
Aims: The aim of the study was to evaluate the prevalence of various histopathological spectra in cholecystectomy specimens and to highlight both the histopathological and clinical findings in gallbladder specimens. Study Design: An analytical cross-sectional study. Place and Dur...
Open access
Research Article10.9734/jpri/2025/v37i87735
N’doman Gossan Roméo, Bibila Mayaya Bisseyou Yvon, Djako Akassa Marius Bernard, Niaré Adama, Akori Esmel Elvice, Kéita Mélalie & Megnassan Eugène·Journal of Pharmaceutical Research International·2025
Abnormal and uncontrolled cell growth leading to dysfunction of cellular metabolism causes a serious disease called cancer. In 2022, 20 million people had cancer and 9.7 million died. Cancer is a real health problem given the number of deaths caused by this disease. This article...
Open access
Research Article10.9734/jpri/2025/v37i87734
Background: Cervical cancer is a serious global health concern, and conventional therapies are frequently linked to significant adverse consequences. For example, cisplatin is the most commonly used conventional chemotherapeutic drug but it will cause serious nephrotoxicity, Hear...
Open access
Research Article10.9734/jpri/2025/v37i87733
Aims: We assessed the significance of direct immunofiuorescence in the diagnosis of vasculitic lesions and to investigaie the hisiopathological characierises of vasculite iesions. Study Design: A cross-sectional study. Place and Duration of Study: The Cross-sectional research was...
Open access
Research Article10.9734/jpri/2025/v37i87732
Anticoagulants represent a category of dosage forms utilized in the treatment of thrombotic disorders, which extend the clotting time. This study focuses on quantifying Edoxaban in solid oral dosage forms. A precise RP-HPLC method was established to ascertain the Edoxaban content...
Open access
Research Article10.9734/jpri/2025/v37i87731
There is a sense of relief among consumers finding BPA-Free tag on various plastic products. But is it true, that a BPA-Free plastic is safe? Various studies suggest that very low dose of BPA can lead to multiple health adversities, including obesity, behavioural problems, reprod...
Open access
Research Article10.9734/jpri/2025/v37i87730