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All published articles 7450

Will Suprahyoid Muscle Release be Effective to Improve Swallowing in Patients with Temporomandibular Disorders? A Single Group Experimental Study

Kavita Joshi, Sukdeb Mahanta, Milind Kahile, Neha Deshmukh, Vivek Patel & Vasant Gawande · Journal of Pharmaceutical Research International · 2021

Background: As for jaw opening force, hyoid resting position and hyoid dynam­ics are very important and are considered to be affected directly by the suprahyoid muscles. MFR is found to be effective in giving symptomatic relief and increasing jaw ROM in patients with myofascial T...

Open access Research Article 10.9734/jpri/2021/v33i64B35337

Study of Fissure Soles: Prevalence and Their Association with Various Dermatoses

Sunil Petkar, Pratima Waghmare, Ketaki Sankhe & Pravin Maheshawari · Journal of Pharmaceutical Research International · 2021

Heel fissures are splits or cracks in the epidermis, which can manifest as a consequence of anhidrosis and may or may not present with hyperkeratosis. Epidermal fissures are superficial and not considered to be a wound at this early stage. However, with increased pressure these spli...

Open access Research Article 10.9734/jpri/2021/v33i64B35422

Coumarin: A Novel Tool for Multidisciplinary Activities

Sonali M. Jadhav, Prajakta V. Adsule, Anuruddha R. Chabukswar, Sushil S. Kore & Krishna S. Shevate · Journal of Pharmaceutical Research International · 2021

Coumarin 2H-1-benzopyran-2-one core has been a field of attention due to its exclusive propensity to accept variable classes of replacements which proves it as the origin for multi-disciplinary activities. Many researchers replicates that coumarin derivatives synthesized by struc...

Open access Research Article 10.9734/jpri/2021/v33i64B35994

Testicular Mass with Liver Metastasis: A Case Report

Yamini Gawande, Suhas Tivaskar, Akash More & Anurag Luharia · Journal of Pharmaceutical Research International · 2021

Background: A malignancy of testicles is known as testicular cancer. The testicles are positioned directly below the penis in the scrotum. The testicles' purpose is to create sperm for reproduction. A lump in the testicles and pain or swelling in the scrotum are the possible symp...

Open access Research Article 10.9734/jpri/2021/v33i64B35339

Nerve Conduction Study in Healthy Elderly Subjects in Central India

Avinash B. Taksande, Alka Rawekar & Sunil Kumar · Journal of Pharmaceutical Research International · 2021

Background: Electrodiagnostic study is performed in a neurophysiology lab diagnosed peripheral neuropathy. Effect of ageing on nerve and muscle inform of muscle contractility decreased, change in the metabolism of muscle and neuromuscular junction transmission and reduced nerve c...

Open access Research Article 10.9734/jpri/2021/v33i64B35424

Recent Developments on Novel Heterocyclic Compounds Thiadiazoles and Heterocyclic Compounds for COVID-19 Targets in Drug Discovery

B. Madhavi & G. Veera Raghava Sharma · Journal of Pharmaceutical Research International · 2021

This article mainly reviews the recent developments in the synthesis of novel 1,3,4-Thiadiazoles and also recent development of drug molecules for the treatment of COVID-19. The Thiadiazole heterocycle and its derivatives are the most important class of compounds among various he...

Open access Research Article 10.9734/jpri/2021/v33i64B36210

Osteometric Measures of Mandible on Its Various Aspects in South Indian Dry Skull

Srivarsha Ranjeet & Dinesh Premavathy · Journal of Pharmaceutical Research International · 2021

Introduction: Mandible is the single bone articulated with cranium forming a temporomandibular joint and it contributes to the lower jaw containing teeth. The mandible is composed of the body and the ramus. Aim: Aim of this study is to find the distance between each parameter in...

Open access Research Article 10.9734/jpri/2021/v33i64B35369

A Study Protocol to Assess the Correlation of Endometrial Morphology with Concerned Hormone Levels in Patients of Abnormal Uterine Bleeding

Tanvi Bhardwaj, Kishor Hiwale & Sunita Vagha · Journal of Pharmaceutical Research International · 2021

Background: Abnormal-uterine-bleeding (AUB) is caused due to numerous systemic or functional etiologies. Patients may come with metrorrhagia, menorrhagia, intermenstrual bleeding and polymenorrhea. The underlying pathology can be ascertained by histological variations of endometr...

Open access Research Article 10.9734/jpri/2021/v33i64B35425

A Study on Branching Pattern of Branches of Middle Meningeal Artery Based on Meningeal Grooves Present in the Cranial Cavity in South Indian Dry Skulls

. Sushmitha & Dinesh Premavathy · Journal of Pharmaceutical Research International · 2021

Aim: To study the branching pattern of branches of the middle meningeal artery based on meningeal grooves present in the cranial cavity. Introduction: Middle meningeal artery is the major human dural artery. It is a neurologically very important artery for treatment and study of...

Open access Research Article 10.9734/jpri/2021/v33i64B35371

A Study of Bcl-2 Immuno-expression in Invasive Ductal Carcinoma of Breast and it’s Correlation with Molecular Sub-types

Poornima Pandey, Arvind Bhake & Sunita Vagha · Journal of Pharmaceutical Research International · 2021

Background: The incidence of Breast cancers has overtaken the cervical cancers amongst Indian females. Invasive Ductal carcinoma is reported to be the most common form of breast cancer. Bcl-2 has been studied extensively as a common factor in the pathogenesis of solid tumours inc...

Open access Research Article 10.9734/jpri/2021/v33i64B35426

Prevalence and Antibiogram of Multidrug Resistant Klebsiella Species

Ulfat Sultana, Tajwar Sultana, Syeda Amber Zaidi, Faiza Qureshi, Yameen Bocha & Tayyaba Kazmi · Journal of Pharmaceutical Research International · 2021

Aim: To find out the prevalence and susceptibility of MDR klebsiella isolates in Karachi. Study Design: Pre-clinical in-vitro study. Place and Duration of Study: Study was conducted at the microbiology lab of the tertiary care hospital of Karachi, Pakistan during May to October 2...

Open access Research Article 10.9734/jpri/2021/v33i64B35373

Comparative Evaluation & Correlation of Severity of Temporo-Mandibular Joint Disorders and Airway Difficulty in Class I and Class II Vertical Growth Pattern Cases

Rizwan Gilani, Sunita Shrivastav, Rozina Vishnani, Pallavi Daigavane, Priyanka Niranjane & Anand N. Wankhede · Journal of Pharmaceutical Research International · 2021

Introduction: There are contradictory opinions regarding the role of occlusal factors in the initiation of TMDs. These patients rarely visit or are referred to Orthodontists or dentists which also accounts for these TMDs being undiagnosed. There is conflicting evidence where most...

Open access Research Article 10.9734/jpri/2021/v33i64B35431

Potential Therapeutic Activity of Mango (Mangifera indica L.) Leaves on Excess Consumption of Fructose in Rats

Alyae M. S. Gabal, H. E. El-Kewawy & Gehan M. Morsy · Journal of Pharmaceutical Research International · 2021

Background and Objective: High fructose consumption has increased worldwide. It causes various metabolic, genetic and histologic alterations. Alternative medicine, primarily herbal plants, has been proposed to alleviate the negative effects of high fructose consumption. The main...

Open access Research Article 10.9734/jpri/2021/v33i64B35386

Correlation of MTHFR Gene Polymorphism with Male Infertility

Akash More, Ujwal Gajbe, Bhagyashree Bhandekar & Deepti Shrivastava · Journal of Pharmaceutical Research International · 2021

Background: Folate is present in Vitamin B, which is not present in the body, and one has to consume it from outside. Its functions are to help in the production of RBCs, helps in the production of genes, DNA, RNA, and protein, helps in the metabolism of homocysteine, and is also...

Open access Research Article 10.9734/jpri/2021/v33i64B35440

Effectiveness of Ginger Candy on Dysmenorrhea among Adolescent Girls of a Nursing College at Vadodara

Aishwaryakumari S. Patel & T. Vinaya Kumary · Journal of Pharmaceutical Research International · 2021

Background of Study: Adolescence period for a girl is a time of physical and mental preparation for a safe mother. Dysmenorrhea is a painful menstrual cycle. It is characterized as painful pelvic pain that begins shortly before or early in the menstruation and lasts 1 to 3 days....

Open access Research Article 10.9734/jpri/2021/v33i64B35423