Topical corticosteroids remain a cornerstone in the management of a wide array of dermatological conditions due to their anti-inflammatory, antiproliferative, and immunosuppressive properties. This article aims to present a clinically relevant case of clobetasol-induced purpura c...
Open access
Research Article10.9734/jpri/2025/v37i77729
Anticoagulant therapy required administration of the oral medications via an enteral feeding tube for the patient who is unable to consume orally. Anticoagulants are class of dosage form used in treatment of thrombotic disorders and to prolong the clotting time. In the proposed s...
Open access
Research Article10.9734/jpri/2025/v37i77728
Dissolution plays an important role as an in-vitro release test for any pharmaceutical product life cycle. Discriminatory dissolution profiles are highly desirable for differentiation between products having differences in their pharmaceutical attributes (formulation and/or manuf...
Open access
Research Article10.9734/jpri/2025/v37i77725
Introduction: Learning disabilities (LDs) are neurodevelopmental disorders that impair academic skill acquisition despite normal or above-average intelligence. In India, these are frequently misunderstood as behavioral issues, leading to stigma, emotional distress, and delayed su...
Open access
Research Article10.9734/jpri/2025/v37i77726
Attention-Deficit Hyperactivity Disorder (ADHD) and age-related cognitive decline are distinct yet overlapping conditions with neurobiological, nutritional, and inflammatory components. This review synthesizes current research on the role of dietary interventions and nutritional...
Open access
Research Article10.9734/jpri/2025/v37i77727
Aim: The rise of multidrug-resistant tuberculosis (MDR-TB) presents a significant challenge to existing treatment approaches, highlighting the urgent need for innovative therapeutic strategies. This research focused on designing siderophore-conjugated meropenem derivatives to tar...
Open access
Research Article10.9734/jpri/2025/v37i77724
Intracranial hemorrhage stands as a profoundly devastating condition characterized by exceptionally high mortality rates. In the absence of clinically validated therapeutic interventions, the management of this condition is predominantly supportive. Given the unfavorable prognosi...
Open access
Research Article10.9734/jpri/2025/v37i77722
The constraint of global pharmaceutical supply chains has been laid bare by a series of adverse events—from the COVID-19 pandemic to war, political conflicts, and climate-induced natural disasters. These critical events have exposed the severe vulnerabilities, including overdepen...
Open access
Research Article10.9734/jpri/2025/v37i77723
Objective: Petroleum pump attendants are constantly exposed to petroleum-derived toxicants, like aromatic hydrocarbons, released into the ambient air during dispensing, and these cause some biochemical changes, including lipid peroxidation. This study investigated possible effect...
Open access
Research Article10.9734/jpri/2025/v37i77720
Non-alcoholic fatty liver disease (NAFLD) is a significant world health burden, occurring in more than 25% of the adult population and advancing to steatohepatitis, fibrosis, and eventually cirrhosis or hepatocellular carcinoma. Although it is increasingly prevalent, there are li...
Open access
Research Article10.9734/jpri/2025/v37i77721
Modern science has gone a long way in elucidating the beguiling properties attributed to the roots of Arnebia nobilis (Boraginaceae) containing Shikalkin (SHK). This compound holds promise as a powerful anti-microbial agent, addressing the persistent problem of microbial resistan...
Open access
Research Article10.9734/jpri/2025/v37i77712
Background: Depression is a mental health disorder characterized by persistent sadness, hopelessness, and loss of interest in activities. During pregnancy, it is referred to as antenatal depression, which can impact both maternal and fetal health. Untreated prenatal depression ca...
Open access
Research Article10.9734/jpri/2025/v37i77711
Background: Diabetes mellitus (DM) is a long term, progressive metabolic disease marked by high blood sugar levels brought on by aberrant insulin action, production, or both. The procedure by which a person applies insulin to subcutaneous tissue is known as self-administration. A...
Open access
Research Article10.9734/jpri/2025/v37i67710
The gut-heart axis represents a critical interface through which gut microbiota influences cardiovascular health and disease. Dysbiosis, characterized by microbial imbalance, contributes to cardiovascular diseases (CVDs) by promoting systemic inflammation and producing harmful me...
Open access
Research Article10.9734/jpri/2025/v37i67709
The demand for beauty and personal care products has increased therefore consumers look towards alternatives in recent years, thereby increasing the popularity of herbal cosmeceuticals arise because they are safe and natural. Herbal extracts are infused with cosmetics or bases wh...
Open access
Research Article10.9734/jpri/2025/v37i67708