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All published articles 7450

The Application of Joint Classroom Discussion Case-Based Learning Teaching Method in the Field of Urology

Muhammad Abbas, Chen Huaian, Zhao Guobin, Zhang Chao, Sibghat Ullah & Kashif Javid · Journal of Pharmaceutical Research International · 2025

In teaching poses significant challenges for clinical doctors and medical students. Students frequently struggle to apply theoretical knowledge in real clinical contexts. We explore the joint discussion of flipped classroom in urological surgery theory teaching case-based learnin...

Open access Research Article 10.9734/jpri/2025/v37i47679

Herbal Formulations in Management of Dermatitis

Arna Pal, Beduin Mahanti & Sudipta Chakraborty · Journal of Pharmaceutical Research International · 2025

Dermatitis, a persistently harmful skin condition, impacts millions of people globally. Redness, itching, and skin lesions are the hallmarks of dermatitis. The need for innovative approaches to therapy is highlighted by the significant side effects and poor efficacy of indigenous...

Open access Research Article 10.9734/jpri/2025/v37i47678

Systematic Implementation of Quality by Design (QbD): A Perspective from Generic Pharmaceutical Industries

Rajanikant Patel, Santosh Kesarpu & Bipin Patel · Journal of Pharmaceutical Research International · 2025

Quality by Design (QbD) is a structured approach to pharmaceutical development that ensures predefined product quality by understanding and controlling manufacturing processes from the outset. Unlike traditional methods focusing on end-product testing, QbD emphasizes building qua...

Open access Research Article 10.9734/jpri/2025/v37i47677

Azadirachta indica Natural Active Ingredients to Cure Mpox: In silico Targeting VP39

Maneesh Kumar, Suman Kumar, Ratnesh Kumar, Mithilesh Kumar Jha, Shashank Nand Tiwari & Pratima Gupta · Journal of Pharmaceutical Research International · 2025

VP39 is an essential enzyme in the Mpox virus acting as methyltransferase for RNA capping to translate viral mRNA during human infection. This enzyme adds a 7-methylguanosine cap at the 5' end of viral mRNAs, imitating the capping mechanism of the host cells to evade immune detec...

Open access Research Article 10.9734/jpri/2025/v37i47676

Analytical Study of Guduchyadi Rasayana: An Ayurvedic Formulation for Academic Stress

Gayatri & Harish Singhal · Journal of Pharmaceutical Research International · 2025

Guduchyadi Medhya Rasayana herb is an Ayurvedic formulation herb that is useful to improve memory. It is utilized for the stress management and improvement of cognitive health in children, advocating for the standardization of the intervention for clinical application in stress r...

Open access Research Article 10.9734/jpri/2025/v37i47675

Structural Elucidation of Some Antibiotics against Wound Bacterial Pathogens from Penicillium Species Using Agrowastes

Ikechukwu Harmony Iheukwumere, Chidiogo Marigold Iheukwumere, Obianuju Helen Obiefuna, Bright Chukwuebuka Unaeze, Michael Ikechukwu Nwike, Amaka Olivia Obianom, Nnenna Nelly Onyemekara, Chimamkpam Henry Nnadozie, Edwin Uchechukwu Igboanugo, Victor Echezona Ike & Nnamdi Enoch Nwakoby · Journal of Pharmaceutical Research International · 2025

Aim: This study was undertaken to carry out structural elucidation of some antibiotics from Penicillium species using Agro-wastes. Methodology: Penicillium species were isolated from garden soil samples, and grown in formulated mycological medium that comprises Phoenix dactylifer...

Open access Research Article 10.9734/jpri/2025/v37i37673

Antimicrobial and Phytochemical Studies of Hydroethanolic Extracts of Plumbago zeylanica (L.), a Medicinal Plant Used against Microbial Infections and Intestinal Disorders

Eyana Teyi, Yao Hoekou, Koffi Eyram Tsetse, Joseph Kokou Hounsrou, Nondomè Sergyne Rosny Kouke & Tchadjobo Tchacondo · Journal of Pharmaceutical Research International · 2025

Antibiotic resistance remains a real public health problem. The search for new molecules to effectively combat this problem is becoming a necessity. The objective of this study was to evaluate the in vitro antimicrobial effect of hydroethanolic extracts of leaves and roots of Plu...

Open access Research Article 10.9734/jpri/2025/v37i47674

Mycological Medium for the Production of Antibiotics against Urogenital Bacterial Pathogens from Natural Sources

Ikechukwu Harmony Iheukwumere, Chidiogo Marigold Iheukwumere, Obianuju Helen Obiefuna, Bright Chukwuebuka Unaeze, Michael Ikechukwu Nwike, Amaka Olivia Obianom, Nnenna Nelly Onyemekara, Chimamkpam Henry Nnadozie, Edwin Uchechukwu Igboanugo, Victor Echezona Ike & Nnamdi Enoch Nwakoby · Journal of Pharmaceutical Research International · 2025

Aim: This study was carried out to evaluate a mycological medium for the production of antibiotics from natural sources. Methodology: Garden soil samples were randomly collected and screened for the growth of Aspergillus species. The isolated fungi were grown in a formulated myco...

Open access Research Article 10.9734/jpri/2025/v37i37671

Effect of Different Extraction Methods on the Concentration of Phenolics and Flavonoids in Catharanthus roseus and Assessment of Their Efficacy for Lifespan Extension in Model Organism Caenorhabditis elegans

Shital Doshi & Vincent Braganza · Journal of Pharmaceutical Research International · 2025

Objective: In the preparation of plant extract, the extraction method plays a crucial role as it can have a significant impact on the quality of secondary metabolites extracted, as well as their stability and concentration. Methodology: The preliminary methodology in this researc...

Open access Research Article 10.9734/jpri/2025/v37i37670

A Structured Review and Critical Analysis of RCTs on Nandrolone Decanoate’s Cardiac Effects in Young Exercising Man

Lucas Caseri Câmara & Diogo Pinto Viana · Journal of Pharmaceutical Research International · 2025

Aims: The cardiovascular risks associated with anabolic-androgenic steroid (AAS) use, particularly nandrolne decanoate (ND), remain a topic of debate due to conflicting evidence from different types of studies. While observational research frequently reports adverse cardiac effec...

Open access Research Article 10.9734/jpri/2025/v37i37669

Norms Establishment with Bolten Analysis for the Central Indian Population

Sneha Sanjay Lambat, Pallavi R. Daigavane, Vikrant Vishwas Jadhav & Ranjit Kamble · Journal of Pharmaceutical Research International · 2025

Objective: To establish the norms for the Bolton analysis in Central India (male and female) population. Materials and Methods: 125 study casts (62 males and 63 females) from 15 to 30 years were selected from the Department of Orthodontics. The mesio-distal dimension from right t...

Open access Research Article 10.9734/jpri/2025/v37i37668

Microbial Contaminants on Medical Devices: A Review

Rekha Manivannan, Chidambaram Tamilselvan & King Solomon Ebenezer · Journal of Pharmaceutical Research International · 2025

Microbial contamination of medical devices is a critical issue in healthcare, as it can lead to serious infections and complications in patients. Medical devices, ranging from simple tools like syringes to complex apparatuses such as ventilators, are integral to modern medical ca...

Open access Research Article 10.9734/jpri/2025/v37i37666

Effect of Foot Reflexology with Aromatic Oil to Assess Sleep Quality among Healthy Individuals: A Narrative Review

Akshatha, Vanitha S Shetty, Lakshmeesh & Prajna Prashant Shetty · Journal of Pharmaceutical Research International · 2025

Objective: The primary objective of this literature review was to evaluate the effectiveness of foot reflexology with aromatic oil to assess Sleep quality among healthy individuals. Introduction: Sleep is a vital activity that offers relaxation, stability, stress release, and the...

Open access Research Article 10.9734/jpri/2025/v37i37667

Metabolic Therapy for Lipedema: Can Tirzepatide Overcome the Treatment Gap?

Diogo Pinto da Costa Viana & Lucas Caseri Câmara · Journal of Pharmaceutical Research International · 2025

Aims: This article reviews the pathophysiological mechanisms of lipedema and explores the potential benefits of tirzepatide as a novel therapeutic approach. Study Design: Opinion article. Place and Duration of Study: Brazil, January–February 2025. Methodology: A critical analysis...

Open access Research Article 10.9734/jpri/2025/v37i37664