Skip to content

All published articles 7450

A Prospective Observational Study on Incidence, Implications and Management of Seizures Following Stroke

Angel Sunny, J.K Alan, Megha S Arali, Sara Babu, Syed Khaleel Ahmed & Vinod Naik · Journal of Pharmaceutical Research International · 2024

Background: Seizures following a stroke often indicate a more severe incident, typically resulting in extended hospital stays and a heightened risk of long-term disability. Management strategies generally include the use of anti-epileptic drugs to mitigate the frequency and sever...

Open access Research Article 10.9734/jpri/2024/v36i127626

Comparative Analysis of Gene Networks in Humans and Model Organisms for Aging Studies

Muthuselvi Gopal & Daniel Alex Anand · Journal of Pharmaceutical Research International · 2024

Aging is the cause of the loss of vitality on a day-to-day basis, a risk factor for developing chronic diseases and ultimately leading to death. This inevitable biological process is yet to be completely understood. A hypothesis states that manipulation of aging process can enabl...

Open access Research Article 10.9734/jpri/2024/v36i127624

Case Report of Locally Advanced Breast Cancer in a 53-Year-Old Women: Diagnosis and Treatment Approach

Rahul Shil & Ruchira Ankar · Journal of Pharmaceutical Research International · 2024

Breast cancer has become the most prevalent cancer among all types of cancer in India, and it poses a serious health concern among women. Locally advanced breast cancer (LABC) and advanced breast cancer collectively represent over 70 percent of all cases of breast cancer. In this...

Open access Research Article 10.9734/jpri/2024/v36i127625

Assessment of Oral Health-related Quality of Life among Adults in Kolkata, West Bengal, India

Surajit Bose, Maumita Bhattacharya, Rakshith Shetty, Subhalaksmi Sen, Ashish Choudhary, Piyali Poddar & Jayanta Chattopadhyay · Journal of Pharmaceutical Research International · 2024

Background: Oral diseases are thought to produce a negative impact on the quality of life of an individual. It is well-documented now a days that the patient's perception should be familiarized while evaluating oral diseases and the respective treatment measures. Hence, it is imp...

Open access Research Article 10.9734/jpri/2024/v36i117622

Linezolid-induced Sideroblastic Anaemia: A Reversible but Overlooked Adverse Effect

Miet D. Shah, Shrinath Kshirsagar, Taher Varawala, Samiksha Sankhe, Manaswi Jadhav & Niharika Gill · Journal of Pharmaceutical Research International · 2024

With the ever-evolving guidelines and changing drug regimens for tuberculosis (TB), it is paramount for treating physicians to understand the efficacy and safety profiles of the drugs being used. Linezolid is included in the treatment of multidrug-resistant (MDR) and extensively...

Open access Research Article 10.9734/jpri/2024/v36i117621

Evaluating Vancomycin Supratherapeutic Dosing and Associated Acute Kidney Injury: A Novel Correlation Factor Equation Applied in an Antimicrobial Stewardship Program

Yazan S. Batarseh · Journal of Pharmaceutical Research International · 2024

This study evaluates the relationship between vancomycin supratherapeutic dosing and acute kidney injury (AKI) through a novel correlation factor equation within an antimicrobial stewardship program. Vancomycin, commonly used to treat serious infections like MRSA, has been associ...

Open access Research Article 10.9734/jpri/2024/v36i117620

A Prospective Observational Study on the Clinical Profile Assessment of Myocardial Infarction Patients in a Tertiary Care Teaching Hospital

Ruksaar Faheen G.M, Hanna Merril Suni, Thriveni C H, Ajmal F, Arathy S S & Varun LAL · Journal of Pharmaceutical Research International · 2024

Background: Cardiovascular Diseases (CVDs) are the single largest contributor to the global burden of disease and are recognized as the leading cause of death globally. CHD has various clinical manifestations ranging from asymptomatic to acute conditions, namely acute coronary sy...

Open access Research Article 10.9734/jpri/2024/v36i117618

Prediction of Lead Molecule Esculetin of Tridax procumbens against Zika Virus Envelope Protein

King Solomon Ebenezer & Rekha Manivanan · Journal of Pharmaceutical Research International · 2024

In the existing field of science, it is necessary for Siddha, Ayurveda therapists, to understand the interactions and to treat the target regions of the human system effectively. One of the most significant nightmares for scientists and medical professionals has been the Zika vir...

Open access Research Article 10.9734/jpri/2024/v36i117619

Factors Influencing Parental Practices Regarding Childhood Immunization in Lahore, Pakistan

Sara Shahid, Hamda Shakir, Maryam Ayesha, Areej Kainat, Qurat-ul-Ain, Ansa Ijaz, Muhammad Ali Tahir, Muhammad Fahad, Maryam Mughal, Minahil Fatima, Umair Amjad & Muhammad Zahid Iqbal · Journal of Pharmaceutical Research International · 2024

Background: Childhood immunization is a key strategy of the World Health Organization (WHO) to reduce child mortality. The vaccine is intended to protect about 2 million and 3 million survivors per year. Despite this, Pakistan continues to struggle with vaccine-preventable diseas...

Open access Research Article 10.9734/jpri/2024/v36i117616

Evaluation of Potential EGFR Inhibitors for Non-small Cell Lung Cancer: A Structure-based Virtual Screening and Molecular Dynamics Study

Gobalan Krishnasamy, Sudharsan Parthasarathy, Shalini Rajasekaran, T. William Raja, S. Geet Andrea & Siva Vijayakumar Tharumasivam · Journal of Pharmaceutical Research International · 2024

Non-small cell lung cancer is a leading cause of cancer deaths globally. EGFR is one of the attractive drug targets for non small cell lung cancer. It was first identified receptor tyrosine kinase receptor. It plays a critical role in the variety of biological activity apoptosis,...

Open access Research Article 10.9734/jpri/2024/v36i117617

Knowledge Gaps Regarding Allergic Rhinitis among the Patients Visiting Community Pharmacies of Lahore, Pakistan

Sara Shahid, Ahmad Hasnat, Fatima Arif, Tameen Amin, Marium Qaiser, Urooj Khalid, Urwah Yousaf, Ayehsa Yousaf, Ehtisham Ahmad, Ali Umer, Wasiq Ali & Muhammad Zahid Iqbal · Journal of Pharmaceutical Research International · 2024

Introduction: Allergic rhinitis is a varied disorder characterized by symptoms such as sneezing, nasal blockage, nasal itching, and a runny nose. This study assessed the knowledge of patients about Allergic rhinitis and to identify knowledge gaps in patient’s understanding along...

Open access Research Article 10.9734/jpri/2024/v36i117615

Formulation and Evaluation of Colon Specific Meloxicam Microcapsules for the Treatment of Arthritis

K Kavitha, Pavan Kumar KS, Ashitha & Yasmeen Taj · Journal of Pharmaceutical Research International · 2024

Objective: The main objective of the current study was to formulate and evaluate meloxicam-loaded microcapsules for colon-specific drug delivery using pH-dependent polymers. The emerging need for developing sustained release NSAIDs to minimize the dosing frequency was the main co...

Open access Research Article 10.9734/jpri/2024/v36i117614

Knowledge and Practice of Community Pharmacists on Amlodipine Use in Karary Locality: A Cross-Sectional Study

Abdallah A. Adam, Mazin Sayed Mohamed Matar, Kannan O. Ahmed & Bashir A. Yousef · Journal of Pharmaceutical Research International · 2024

Background: Amlodipine is one of the most commonly prescribed medications for treating hypertension. Community pharmacists play a crucial role in ensuring patients adhere to their treatment regimens and in counseling them regarding the appropriate dosage and expected side effects...

Open access Research Article 10.9734/jpri/2024/v36i117613

Adverse Drug Reactions and Safety Profiles in Cardiovascular Drug Therapy: A Pharmacovigilance Analysis

Mansoori Izhar., Kumar Prashant., Rai Gopal. & Dave Shuchi. · Journal of Pharmaceutical Research International · 2024

Aims: The purpose of the study is to identify adverse drug reactions (ADRs) and evaluate patient knowledge of the disease using the Knowledge Assessment Questionnaire (KAQ). This study was designed to compare adverse effects on Cardiovascular Drug Therapy. Adverse drug reaction (...

Open access Research Article 10.9734/jpri/2024/v36i117612

Uveitis as a Predictor for Myocardial Infarction in Patients with Behçet's Disease, Multi Centric Cohort Study from Aseer Region, Saudi Arabia

Nouf Alhammadi, Mushary Alqahtani, Khaled A. Amer, Abdullah AL Thawwab, Ahmed S. AL Zomia, Hanan Alqahtani, Fares A. Alshahrani, Abdussalam Alqhtani, Dalia A. Al Mubarak, Fahad S. Alahmari, Shahad S. Al-Qahtani, Muhammed A. Alkhairi, Noura S. Alhudaithi & Hind A. Asiri · Journal of Pharmaceutical Research International · 2024

Introduction: Behçet's disease (BD) is a chronic, multisystem inflammatory disorder characterized by a diverse array of clinical manifestations, including recurrent oral and genital ulcers, ocular inflammation, skin lesions, and joint problems. Its presentation varies, requiring...

Open access Research Article 10.9734/jpri/2024/v36i117611