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All published articles 7450

Study on the Anti-cancer Potential of Aegle marmelos Fruit Extract Pro and Anti Apoptotic Molecule in Human Melanoma Cell Line-A375

G. V. Venkatakarthikeswari, R. Gayatri Devi, J. Selavaraj & A. Jothi Priya · Journal of Pharmaceutical Research International · 2021

Aegle marmelos is also known as bael which is commonly found in south East Asia and Indian-sub continent. The origin of bael is India. Bael is also known as the golden apple, Bengal-quince in India. In the ancient medical system, Aegle marmelos play an important role and its extr...

Open access Research Article 10.9734/jpri/2021/v33i59A34273

Optimization and Characterization of Self Nano Emulsifying Drug Delivery System loaded with 18- β Glycyrrhetinic acid

Heena Farooqui & Prashant Upadhyay · Journal of Pharmaceutical Research International · 2021

The purpose of this study was to prepare, optimize and evaluate self nano emulsifying drug delivery system (SNEDDS) containing 18- β glycyrrhetinic acid which enhances the dissolution profile or bioavailability of the drug in comparison to pure suspension of 18- β glycyrrhetinic...

Open access Research Article 10.9734/jpri/2021/v33i59A34275

Resistance Exercise Reduces the Necessity for Hypoglycemic Agent (Humulin) in Overweight Women with Gestational Diabetes Mellitus

P. Selvi, V. Manivannan, G. Liji Martina, V. Senbagavalli, C. Selvin Thanuja & N. Rengarajan · Journal of Pharmaceutical Research International · 2021

Background: Gestational Diabetes Mellitus (GDM) is currently treated with blood sugar monitoring, nutritional supplements, increased fatal police work, and hypoglycemic agent medical help PRN to achieve and maintain normoglycemia. Even though humulin therapy has been demonstrated...

Open access Research Article 10.9734/jpri/2021/v33i59A34276

Ameliorating the Effect of Mycotoxins in Poultry Feeds Using Plant Extracts

A. R. Varalakshmi, A. Josephine, R. Kunguma Priya & K. Revathi · Journal of Pharmaceutical Research International · 2021

Mycotoxins are toxic secondary metabolites of fungal origin that tends to contaminate agricultural commodities before or under post-harvest conditions. They are mainly produced by fungi in the genera, Aspergillus sp. (Aspergillaceae: Eurotiales), Penicillium sp. (Trichocomaceae;...

Open access Research Article 10.9734/jpri/2021/v33i59A34277

Antibacterial Activity of Padikara Parpam against ESBL Producing Escherichia coli and Klebsiella pneumoniae

Anitha Akilan, Josephine Anthony & Revathi Kasthuri · Journal of Pharmaceutical Research International · 2021

Aims: To evaluate the antibacterial activity of Padikara Parpam against Extended-Spectrum Beta-Lactamase (ESBL) producing Escherichia Coli and Klebsiella Pneumoniae using agar well diffusion method. To identify ESBL producing bacteria by phenotypic confirmatory test using disk di...

Open access Research Article 10.9734/jpri/2021/v33i59A34278

Effect of Enzymatic Changes in Vitamin D Combination with LIV-52 on Carbon Tetrachloride Induced Liver Disease in Wistar Rats

K. Ponnazhagan, Ursula Sampson, N. Muninathan, J. Pratheeba, B. Sumanth Kumar & I. Jaiganesh · Journal of Pharmaceutical Research International · 2021

Aim: The present study was conducted to investigate the hepatoprotective effect of enzymatic changes in vitamin D combination with Liv-52 on CCl4 induced liver toxicity in Wistar rats.  Background: The central organ of liver plays an essential vital role in the metabolism, and th...

Open access Research Article 10.9734/jpri/2021/v33i59A34279

A Comparative Study to Assess Compassion Fatigue, Burnout and Compassion Satisfaction among Casualty Nurses with Intensive Care Unit Nurses at Selected Hospitals in Vadodara

Sachin Sadanandan, Lakhan Kataria, V. Suresh & Sajitha Sadanandan · Journal of Pharmaceutical Research International · 2021

Aim: This study is focussed on comparison and assessment of compassion fatigue, burnout and compassion satisfaction among casualty nurses with intensive care unit (ICU) nurses. Study Design: Quantitative research approach and Descriptive - Comparative research design. Materials a...

Open access Research Article 10.9734/jpri/2021/v33i59A34281

Evaluation of Nephroprotective Activity of Laportea interrupta Leaf Extract in Experimental Animals

Puneeth Kumar Shetty & Prasanna Shama Khandige · Journal of Pharmaceutical Research International · 2021

Laportea interrupta also called as Hen’s Nettle is a primitive plant that is known for its property of causing itch after its touch. This plant has been found useful in treating pre maternal health, anti-pyretic and anti-inflammatory action. Previously conducted scientific studie...

Open access Research Article 10.9734/jpri/2021/v33i59A34283

Serological Changes of Monoclonal Antibody CAMA3C8 against Human Breast Cancer Cell Line

N. Muninathan, K. Ponnazhagan & T. S. Meghalatha · Journal of Pharmaceutical Research International · 2021

Background: Tumor associated antigen are glycoproteins and glycolipids expressed on the surface or in the cytoplasm of tumor cells. The antigenic components are shed from the tumor cells into the tissue culture medium or blood or other human body fluids like human milk. Objective...

Open access Research Article 10.9734/jpri/2021/v33i59A34284

Estimation of Variations in the Erythrocyte Sedimentation Rate in COVID-19 Recovered Patients

Manoj Aravindan, Palati Sinduja, R. Priyadharshini & V. Meghashree · Journal of Pharmaceutical Research International · 2021

Background: A cluster of patients with pneumonia and severe acute respiratory syndrome developed in Wuhan, China in December 2019, and infection with a novel coronavirus virus called COVID -19 was later verified. Although fever and cough were the most common early signs and sympt...

Open access Research Article 10.9734/jpri/2021/v33i59A34285

Frequency of Leading Factors of Severe Acute Malnutrition in Children Below Five Years of Age Attending National Institute of Child Health, Karachi

Iqra Rafique Khokhar, Mohsina Noor Ibrahim, Sanam Khan, Aiysha Farhat, Farah Jamil & Muhammad Nadeem Chohan · Journal of Pharmaceutical Research International · 2021

Aim: To determine the frequency of leading factors of severe acute malnutrition in children below five years of age. Study Design: Cross-sectional study. Place and Duration of Study: Outpatient department, National Institute of Child Health (NICH) Karachi from December 7, 2017 to...

Open access Research Article 10.9734/jpri/2021/v33i59A34289

COVID-19: Source, Symptoms, Screening, Prevention and Treatment

Nikita Suda, Rakesh Kumar Jha & Supriya Meshram · Journal of Pharmaceutical Research International · 2021

Background: COVID-19 is an infectious disease caused by the newly acquired SARS-COV2 virus. The disease is rapidly changing, as well as our understanding of the emerging virus. Not knowing what it was at the beginning of the year 2020, scientists have been able to classify, track...

Open access Research Article 10.9734/jpri/2021/v33i58A34147

Nephroprotective Activity of Ethanolic Extract of Carissa carandas Leaves against Gentamicin-Induced Acute Kidney Injury in Wistar Albino Rats

V. V. Rajesham, Hima Sowmya Kandoti, Mitta Raghavendra, P. Roshan Ali & T. Rama Rao · Journal of Pharmaceutical Research International · 2021

The present study was aimed to evaluate the nephroprotective activity of ethanolic extract of Carissa carandas Linn. Leaves (EECC) in Gentamicin-induced nephrotoxicity in Wistar albino rats. The renal damage was induced by Gentamicin (80mg/kg body weight, i.p.). Nephroprotective...

Open access Research Article 10.9734/jpri/2021/v33i58A34117

Level of Awareness and Knowledge of Folic Acid Intake among Women in the Reproductive Age in ARAR Region, Saudi Arabia

Abdulrahman Mazki Alanazi, Abdullah Juayf Alanazi, Yasir Wadi Alanazi, Muhammad Sari Alanazi, Ghada Rezk & Sabry Mohamed Hammad · Journal of Pharmaceutical Research International · 2021

Background: Folic acid reduces the risk of neural tube defects. As approximately 50% of pregnancies are unintended, women of reproductive age should be aware of the importance of folic acid. This study aims to assess the level of awareness and knowledge among childbearing female...

Open access Research Article 10.9734/jpri/2021/v33i58A34118