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All published articles 7450

Stability of Insulin on Polycaprolactone Nanoparticles as a Function of Surface Properties

Nader I. Namazi · Journal of Pharmaceutical Research International · 2021

The purpose of this research was to formulate insulin-loaded polycaprolactone (PCL) nanoparticles and evaluate structural stability of the protein using fluorescence spectroscopy. The size and morphology of the nanoparticles were characterized using dynamic light scattering (DLS)...

Open access Research Article 10.9734/jpri/2021/v33i56B33956

Prednisolone Loaded Tamarind Gum Microspheres for Colonic Delivery

Harish K. Kunjwani & Dinesh M. Sakarkar · Journal of Pharmaceutical Research International · 2021

The aim of this work was to formulate a novel multiparticulate system having pH sensitive property and specific enzyme biodegradability for colon specific drug delivery of Prednisolone (PD). Natural polysaccharide, Tamarind gum is used for microsphere preparation and Eudratit S-...

Open access Research Article 10.9734/jpri/2021/v33i56B33959

Case Report – Accidental Epidural Catheter Breakage and Its Management

Karuna Taksande, Krishnendu S., Nikhil Bhalerao, Jui Jadhav, Dnyanashree Wanjari & Aditi Shatalwar · Journal of Pharmaceutical Research International · 2021

Aim: Epidural anaesthesia which is preferred in most of the prolonged and painful procedures can be dreadful when the catheter breaks inside. In this case report we report accidental breakage of epidural catheter and its successful management. Presentation of Case: 47 year old ma...

Open access Research Article 10.9734/jpri/2021/v33i57A33961

Incidence of Erectile Dysfunction in Patients of Diabetes Mellitus

Yar Muhammad Tunio, Ruqayya Farhad, Abdul Ghaffar Dars, Ghullam Mustafa Mangrio, Ummama Laghari & Tarique Shahzad Chachar · Journal of Pharmaceutical Research International · 2021

Aim: The goal of this study was to determine how frequent erectile dysfunction is in diabetic people and what factors contribute to this condition. Methods:  In this study, type-2 diabetes patients were selected among outpatients who visited Diabetes Clinics regularly. For the fi...

Open access Research Article 10.9734/jpri/2021/v33i57A33962

Effectiveness and Outcome of Early Weight Bearing in Ankle Fracture: A Systemic Review

Abdulmalik B. Albaker · Journal of Pharmaceutical Research International · 2021

Introduction: Ankle fractures are claimed to affect 70-185 patients out of 100,000 people each year. There is currently no unanimity among surgeons throughout the world on early versus restricted weight bearing in surgically treated trauma patients with fractures. The aim of this...

Open access Research Article 10.9734/jpri/2021/v33i57A33963

Overview on Acute Poststreptococcal Glomerulonephritis in Pediatrics: A Review

Ahmed Abdelsamie Fadl, Hiba Saud H. Aldubaib, Nof Tarq F. Alzayyat, Mohammed Abdullah S. Alzahrani, Alshammasi, Mustafa Mohammed A., Fatimah Arif S. Alabbad, Ashjan Aqeel Q. Alanzl, Al Jalooud, Hassan Haeider A, Aseel Saud S Alrefaei & Mohammed Marwan Ahmed Alattas · Journal of Pharmaceutical Research International · 2021

Acute poststreptococcal glomerulonephritis (APSGN) is the most common kind of post-infectious glomerulonephritis and is caused by group A streptococcus (Streptococcus pyogenes). Although the prevalence of PSGN has decreased in affluent nations, non-streptococcal species are becom...

Open access Research Article 10.9734/jpri/2021/v33i57A33965

An Unusual Presentaton of Tuberculosis with Septic Shock and Immune Reconstitution Inflammatory Syndrome in an Immunocompetent Patient

Suraj Patil, K. Mayilananthi, Durga Krishnan, E. Dhivya & V. R. Mohan Rao · Journal of Pharmaceutical Research International · 2021

Tuberculosis presenting as septic shock is a rare entity especially in an immunocompetent patient. It has been reported in only 1% of patients with septic shock. Tuberculosis associated immune reconstitution inflammatory syndrome (IRIS) is the paradoxical worsening of the current...

Open access Research Article 10.9734/jpri/2021/v33i57A33980

Out of Pocket Expenditure Associated with COVID 19 Pandemic in India

Hanitha Rajasekar, U. Sharath & S. Lokesh Kumar · Journal of Pharmaceutical Research International · 2021

Corona virus 2019, popularly known as COVID-19 is a viral illness which has caused a threat in the minds of people across the world in recent times. Even developed countries are facing major challenges in preventing and treating this dreadful disease. In view of unavailability of...

Open access Research Article 10.9734/jpri/2021/v33i57A33982

Protocol on to Assess the Effectiveness of Planned Teaching on Knowledge Regarding to Adverse Effect of Antipsychotic Agents among Caregivers of Schizophrenia Patient

Deepti Ekhar, Pooja Kasturkar & Jaya Gawai · Journal of Pharmaceutical Research International · 2021

Background of the Study: The involvement of caregivers in treatment has been known as a vital part of mental health care. The enlarged emphasis on caregiver partaking has been to some extent driven by the shift from hospitals to primary provision of schizophrenia care in the comm...

Open access Research Article 10.9734/jpri/2021/v33i57A34011

Relationship between Skeletal Maturity, BMI Percentile and Dental Caries Experience among Taster and Non-taster Children

Vinaya Kumar Kulkarni, Shradhda S. Gavade, Neeta Padmawar, Shridhar Shetty & Sourabh Joshi · Journal of Pharmaceutical Research International · 2021

Introduction: Ability of an individual to taste phenylthiocarbamide (PTC) substance divides the population in tasters and non-tasters. The objective of this study was to investigate the relationship between the taste ability for PTC substance with BMI percentile, skeletal maturit...

Open access Research Article 10.9734/jpri/2021/v33i57A33964

Overview on Gastrointestinal Foreign Bodies in Children

Ahmed Abdelsamie Fadl, Asma Awad M. Alhazmi, Tariq Mohammed Alyami, Najla jaber Alkhaldi, Abdulshaheed Salman Alhamdan, Waad Musayid Alsaedi, Yazeed Nashi M. Alaufi, Meshary Saud Almotiry, Ashwaq Laili Alanazi & Hussain Hassan Alrashdi · Journal of Pharmaceutical Research International · 2021

Introduction: Greatest percentage of the upper gastro intestinal accidently swallowed foreign bodies in adults are related to food bolus impaction with meat. Most patients who swallow a true foreign body typically are younger, however young children were recorded to accidently sw...

Open access Research Article 10.9734/jpri/2021/v33i57A33967

Management of Acute Kidney Injury in Patient with Dengue and COVID-19 Illness Simultaneously

Satish Mahajan, Vankadari Venkata Sesha Satya Sagar, Dhruv Talwar, Annadatha Akhilesh & Chitturi Venkata Sai Akhil · Journal of Pharmaceutical Research International · 2021

Dengue is a viral illness spreads through the bite of Aedes aegypti mosquito leading to a serious health hazard. Dengue induced acute kidney injury is a fatal consequence and there are very few studies reported. Hence early identification of high risk groups is crucial for preven...

Open access Research Article 10.9734/jpri/2021/v33i57A33981

Lifitegrast Ophthalmic Solution – A Review

S. Padmaja & K. Lakshitha Niyatee Rao · Journal of Pharmaceutical Research International · 2021

Introduction: In this review article the safety and efficacy of of Lifitegrast™ in the management of dry eye disease is described. Methods: Search was carried out using related search terms in data bases like pubmed and related articles were referred. Result: A larger reduction i...

Open access Research Article 10.9734/jpri/2021/v33i57A33984

Case Report on Gastric Carcinoma

Prachi Kamble, Samrudhhi Gujar, Savita Pohekar, Ranjana Sharma, Sheetal Sakharkar, Arti Raut, Archana Dhengare & Pranali Wagh · Journal of Pharmaceutical Research International · 2021

Introduction: Gastric cancer or stomach cancer is an any malignant tumor arising from the region extending between the gastroesophageal (GE) junction and the pylorus. The incidence and mortality of gastric cancer have been declining in most developed countries. The age-adjusted r...

Open access Research Article 10.9734/jpri/2021/v33i57A34009

Assess the Psychosocial Problem Faced by the Primary Caregivers of Mentally Challenged Children

Achal Jiwane, Ragini Joshi, Divyani Kanholkar, Shreya Kapgate & Deeplata Mendhe · Journal of Pharmaceutical Research International · 2021

Background: It is estimated that up to 20% of children worldwide suffer from debilitating mental illness. Learning disabilities, ADHD, depression, psychosis, pervasive developmental disorders, attachment disorders, anxiety, and conduct disorder are all serious mental illnesses. L...

Open access Research Article 10.9734/jpri/2021/v33i57A34012