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All published articles 7450

Attentive Evaluation of Trace Elements in Patients with Breast Cancer-A Cross Sectional Study of Nawabshah, Sindh, Pakistan

Hazooran Lakhan, Ambreen Qureshi, Khalil Ahmed Memon, Masood Ahmed, Maimoona Khushk, Farheen Shaikh & Arslan Ahmer · Journal of Pharmaceutical Research International · 2021

Background: Breast cancer has recently become one of the most obsessing and life threatening issues in the world. Globally, females suffered mostly by breast cancer. Breast cancer is multifactorial etiological disorder. Trace elements are acts as cofactors and biological catalyst...

Open access Research Article 10.9734/jpri/2021/v33i57B34040

Antioxidant and Xanthine Oxidase Inhibitory Potential of Aqueous Extract of Ferula Asafoetida

G. G. Gopika, R. Gayathri, V. Vishnu Priya, J. Selvaraj & S. Kavitha · Journal of Pharmaceutical Research International · 2021

Background: Ferula asafoetida is a dried latex that is exuded from rhizome or taproot species. Organosulfides are primarily responsible for flavour and odour of asafoetida.Ferula asafoetida is a natural medicine good for asthma and bronchitis. is also used to relieve stomach gas,...

Open access Research Article 10.9734/jpri/2021/v33i57B34042

Exercise as an Emerging Factor Effecting Cardiovascular Health (An Experimental Approach)

Alamgir khan, Muhammad Zafar Iqbal Butt, Shahzaman Khan, Abdul Jabbar Tanweer, Abdul Manan Tanweer, Samiullah khan, Muhammad Jamil, Muhammad Roman Al-Ala Duranni & Zeliha Selamoglu · Journal of Pharmaceutical Research International · 2021

This resaerch study was basically carried out for the purpose to assess the effect of moderate intensity exercise on cardiovascular health. Ten (10) participants were voluntarily selected and thus they were randomly divided into two (02) groups i.e. (Experimental Group (EG)=05+ C...

Open access Research Article 10.9734/jpri/2021/v33i57B34046

Synthesis, Characterization of Some New 1,3,5-Trisubstituted Pyrazole Derivatives for Their Antifungal Potential

Anupam Sharma, Alok Pal Jain & Mayank Gangwar · Journal of Pharmaceutical Research International · 2021

The aim of the study was to develop, synthesis, and characterise a novel 1,3,5-trisubstituted-2-pyrazolines derivative, as well as to evaluate its antifungal activity. The reaction of chalcone derivatives with succinic hydrazide in the presence of pyridine yielded the 1,3,5-tri-s...

Open access Research Article 10.9734/jpri/2021/v33i57B34048

Neuroimaging Assessment of Aggressive Pituitary Adenomas

Khalimova Zamira Yusupovna & Azimova Ozoda Talatovna · Journal of Pharmaceutical Research International · 2021

Aggressive pituitary adenomas (APA) are adenomas that show rapid growth, invasiveness, frequent or multiple relapses, or are resistant to conventional therapies. Clinical-imaging assessment of aggressive pituitary adenomas with the aid of magnetic resonance imaging (MRI) plays an...

Open access Research Article 10.9734/jpri/2021/v33i57B34056

Spectrum of Lesions in the Fallopian Tubes – A Histopathogical Study

Maanasa Palani & Volga Harikrishnan · Journal of Pharmaceutical Research International · 2021

Introduction: The Fallopian tubes are a pair of narrow tubular structures connecting the ovary and the uterus. It is usually the site of fertilization and plays a very important role in the fusion of the sperm and ovary and helps in movement of the fertilized zygote to the uterus...

Open access Research Article 10.9734/jpri/2021/v33i57B34059

Comparison of Random Blood Sugar and pH of Blood- A Clinicopathological Study

P. Titus Lalith Antony, Palati Sinduja & R. Priyadharshini · Journal of Pharmaceutical Research International · 2021

Aim: This study aims to compare the random blood sugar pH of the blood. Introduction: Hyperglycemia is a risk factor for the impairment of periodontal health while periodontal disease, in turn, is responsible for the adverse effects on glycemic control and the pathophysiology of...

Open access Research Article 10.9734/jpri/2021/v33i57B34060

Histopathological Spectrum of Breast Carcinoma in a Tertiary Care Centre and its Association with ABO Blood Grouping and Rh Typing

T. Mitila, P. S. Muthu Subramanian, Chitra Srinivasan & Vimal Chander · Journal of Pharmaceutical Research International · 2021

Background: Globally, breast cancer contributes to 27.7% of the newly diagnosed cases of cancer among women. Early screening and timely diagnosis of the lesions of breast help in alleviating the anxiety among patients. Histopathology is the gold standard in diagnosing the lesions...

Open access Research Article 10.9734/jpri/2021/v33i57B34061

Distribution of Four Biofilm Associated Gene among A. baumannii by in Silico-PCR

J. D. Monesh Babu, A. S. Smiline Girija, P. Sankar Ganesh & J. Vijayashree Priyadharsini · Journal of Pharmaceutical Research International · 2021

Background: A.baumannii is an opportunistic pathogen known for its efficient biofilm formation that is attributed for its virulence. Acinetobacter baumannii is an inhabitant of oral biofilms as well. Many gene operons are involved in the biofilm formation that need to be monitore...

Open access Research Article 10.9734/jpri/2021/v33i57B34062

An Efficient Synthesis of Anti-spasmodic Drug Mebeverine Hydrochloride

V. S. R. N. Phanikumar & G. Veera Raghava Sharma · Journal of Pharmaceutical Research International · 2021

An efficient synthetic process for an antispasmodic drug and active pharmaceutical ingredient of Mebeverine hydrochloride 1 is reported in this communication. It is used for stomach cramps and irritable bowel syndrome (IBS). The treatment for irritable bowel syndrome involves lot...

Open access Research Article 10.9734/jpri/2021/v33i57B34063

Synthesis, Docking and Antimicrobial Activity of Some New Coumarin Incorporated Thiazole Derivatives

Abhishek Kumar, Pankaj Kumar & Aravinda Pai · Journal of Pharmaceutical Research International · 2021

Synthesis and screening of a series of new coumarin derivatives coupled with thiazole are performed for their antimicrobial properties. A series of new thiazolyl coumarin derivatives were synthesized upon refluxing 3-bromoaceytl coumarin, substituted benzaldehyde and thiosemicarb...

Open access Research Article 10.9734/jpri/2021/v33i57B34064

The Psychology behind Luxury Consumption

Shradha Thani & Arpita Sharma · Journal of Pharmaceutical Research International · 2021

This paper will talk about the psychology of consumption of luxury products and experiences and how individuals get emotionally connected to them. This paper discussed new drivers, forms, and consequences of luxury spending. Also, the belief that the psychology of luxury consumpt...

Open access Research Article 10.9734/jpri/2021/v33i57B34065

Measurement of Plasma Fibrinogen Levels, PT and APTT among HIV Infected Patients: A Critical Bio-Marker for Coagulation Dysfunctions

Allageya Yousif Khailfa Ahmed, Nasr Eldeen Ali Mohammed Gaufri, Sara Abdelgani & Lienda Bashier Eltayeb · Journal of Pharmaceutical Research International · 2021

Background: The literature stated that Human immunodeficiency virus (HIV) infection led to activation of coagulation, and habitually linked with an augmented risk of venous and arterial thrombosis. So the purpose of the study was to determine the plasma fibrinogen level in Sudane...

Open access Research Article 10.9734/jpri/2021/v33i57B34066

Anti-bacterial Efficacy of Probiotics used in Provisional Polymethyl Methacrylate Crowns against Porphyromonos gingivalis – an In vitro Study

Hemamalini Balaji, R. Kirupa Shankar, N. Shanmuganathan, N. Parthasarathy & I. Athiban · Journal of Pharmaceutical Research International · 2021

Aim: To evaluate the effect of Probiotic used in PMMA Temporary restorations on gingival inflammatory response by its action on the marginal gingival epithelial cells. Materials and Methods:  This is an in vitro Interventional pilot study using discs of  PMMA ( Group A ) and PMMA...

Open access Research Article 10.9734/jpri/2021/v33i57B34068

Comparison of NS1 Antigen Detection by Rapid Immunochromatography Test and ELISA for Early Diagnosis of Dengue at a Government General Hospital, Ananthapuramu

Adireddi Paradesi Naidu, Chitralekha Saikumar, G. Sumathi, Kalavathy Victor & N. S. Muthiah · Journal of Pharmaceutical Research International · 2021

Background: The incidence of Dengue hemorrhagic fever, Dengue shock syndrome associated with Dengue can be reduced by diagnosing Dengue early and by initiating early treatment to Dengue patients. This study was conducted to compare results of NS1 antigen rapid test and ELISA in c...

Open access Research Article 10.9734/jpri/2021/v33i57B34069