Umair Amjad, Wasiq Ali, Talha Rehman, Muhammad Aamir, Mahnoor Shahzadi, Abdullah, Muhammad Ahmed Saeed, M. Sohaib Sultan Sabri, Adeel Salah, Mahnoor Qaisar & Muhammad Zahid Iqbal·Journal of Pharmaceutical Research International·2024
Background: Over-the-Counter (OTC) medications are the drugs that do not require prescription. In earlier times, self-medication of OTC drugs was not considered a healthy practice. But now FDA stated that “when these medications are used according to guidelines, they are consider...
Open access
Research Article10.9734/jpri/2024/v36i97583
Tabinda Razzaq, Raza Hanif, Muhammad Haris Pervaiz, Shehzada Muhammad Afaq Raza, Samar Zia, Mahgull Mahmood, Muhammad Shahmir Ahsan, Rania Ahmad, Mohammad Abdullah, Wasaeia Riaz, M. Hassan Fayyaz & Muhammad Zahid Iqbal·Journal of Pharmaceutical Research International·2024
Background: Globally, cardiovascular diseases (CVDs) continue to be the primary cause of morbidity and mortality. Conditions including dyslipidemia, ischemic heart disease (IHD), and stroke play a significant role in this regard. Community pharmacists are essential in promoting h...
Open access
Research Article10.9734/jpri/2024/v36i97581
Background & Objective: Cancer is a serious public health concern, particularly in developing countries. The current investigation was to discover novel EGFR and aromatase inhibitors utilizing ligand- and structure-based drug development techniques. This study also focuses on...
Open access
Research Article10.9734/jpri/2024/v36i97582
This comprehensive review provides a pioneering analysis of the instrumental role of Liquid Chromatography with Mass Spectrometry (LC-MS) in unravelling the bioavailability and bioequivalence of Febuxostat (FBS) in human plasma. Utilizing Febuxostat d9 and d7, along with other dr...
Open access
Research Article10.9734/jpri/2024/v36i97580
Hyperlipidemia, is a major stake for the development of serious diseases like atherosclerosis, Coronary Artery Diseases, Stroke. Siddha system of Medicine with the numerous combination of medicines has Manjal Noiku Kudineer(MNK), a Siddha poly herbal formulation indicated for Man...
Open access
Research Article10.9734/jpri/2024/v36i97579
Background: The rising number of chronic illnesses such as asthma, diabetes, osteoarthritis, hypertension, and chronic kidney disease (CKD) presents a major danger to the worldwide health community. The ability of individuals to successfully manage their medical problems with the...
Open access
Research Article10.9734/jpri/2024/v36i97578
The intricate interplay between pharmacokinetics and pharmacodynamics is pivotal in optimizing gentamicin therapy for neonates, a population characterized by unique physiological developmental considerations and pathophysiological changes in critically ill neonates. Rapid growth,...
Open access
Research Article10.9734/jpri/2024/v36i97577
Rachael Olakunmi Ogunye, Donatus Egwuatu, Peter Chidendu Anene, Eberechukwu Osinachi Azubuike, Oluwabusola Oluwakorede Asenuga, James Ponman Sargwak, Jane-Frances Chinenye Ojobor, Favour Ogheneoruese Onoharigho & Chibuzo Valentine Nwokafor·Journal of Pharmaceutical Research International·2024
Emerging technologies present a transformative potential for pharmaceutical process design and optimization, particularly within Africa’s evolving pharmaceutical industries. The purpose of this review is to explore the impact of emerging digital technologies, including Artificial...
Open access
Research Article10.9734/jpri/2024/v36i97576
The commencement of the "St. Patrick's day geomagnetic storm" on March 17th, 2015 led to multiple fluctuations in electron density within the ionosphere, resulting in significant disruptions in Total Electron Content at high latitudes in the northern hemisphere. Through the utili...
Background: Rheumatic heart disease is caused secondary to rheumatic fever. Rheumatic fever, a systemic immune response to a beta-hemolytic streptococcal throat infection, remains a significant health issue in developing countries. Clinical Findings: This is a case report of Rheu...
Open access
Research Article10.9734/jpri/2024/v36i97575
The global Coronavirus disease 2019 (COVID-19) pandemic, caused by Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, has indeed seen the emergence of multiple variants. There are several direct-acting antiviral drugs that have been approved or are in process...
Open access
Research Article10.9734/jpri/2024/v36i97574
Aim: To overcome the logistical hurdles associated with cryostorage, cell therapy products would benefit from being stored as a (freeze-) dried product. However, there is currently unfortunately not a lot of focus in the field to evaluate formulations for their capabilities to pr...
Open access
Research Article10.9734/jpri/2024/v36i97573
This research examines the impact of the U.S. FDA's Regenerative Medicine Advanced Therapy (RMAT) designation on biotechnology and small pharmaceutical companies, focusing on both stock price reactions and drug development timelines. The research employs an event-study methodolog...
Open access
Research Article10.9734/jpri/2024/v36i97572
The growing interest in microsponge-based topical formulations compared to traditional ones is shaping the future of skincare and pharmaceutical treatments. Microsponges are gaining attention for their ability to enhance drug stability, control release, and target specific areas,...
Open access
Research Article10.9734/jpri/2024/v36i87571
We have undertaken to evaluate the pharmacological studies of Gymnema sylvestre using pharmacolical methods,disc diffusion, and anti-inflammatory methods. The Alkaloid, Carbohydrate, Protein,Resin, Saponin, and Glycosides were present whereas, steroid, flavanoid, and tannin were...
Open access
Research Article10.9734/jpri/2024/v36i87570