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All published articles 7450

Formulation, Development, Evaluation and Solubility Enhancement of Lercanidipine Hydrochloride by Solid Dispersion Techniques

S. D. Mankar & Punit R. Rachh · Journal of Pharmaceutical Research International · 2021

Background: Solid dispersions (SDs) are the dispersion of hydrophobic drugs in an inert hydrophilic carrier. SDs are prepared to improve the dissolution properties and bioavailability of slightly water-soluble drug molecules by dispersing them into an inert hydrophilic carrier. A...

Open access Research Article 10.9734/jpri/2021/v33i53B33697

Alteration in the Efficacy of in Vitro Vancomycin and Ceftazidime Prepared in Normal Saline Versus Balanced Salt Solution in the Management of Ocular Infections

Hussain Ahmad Khaqan, Laraib Hassan, Sabah Eric, Hasnain Muhammad Buksh, Raheela Naz & Muhammad Ali Haider · Journal of Pharmaceutical Research International · 2021

Objective: The purpose of this review article is to highlight the efficacy of Vancomycin and Ceftazidime formulated in different solutions for ocular use in the management of microbiological Ocular infections varies. Methodology: To locate and assess all relevant literature, we e...

Open access Research Article 10.9734/jpri/2021/v33i53A33666

Prevalence of Anemia, Iron Deficiency during the Second Trimester of Gestation in Pregnant Women: A Comparative Study of Walled and New Lahore City Population

Shafia Arshad, Amina Arif, Nessar Ahmed & Javed Iqbal Wattoo · Journal of Pharmaceutical Research International · 2021

Background: Anemia during pregnancy is common worldwide, and it is also reported in Lahore, Pakistan, but it is not well documented in women residing in the Walled City of Lahore (WC). The study was designed to compare the pregnant female population of walled and new Lahore (NC)...

Open access Research Article 10.9734/jpri/2021/v33i53A33664

Qualitative and Quantitative Determination of Secondary Metabolites and Antioxidant Potential of Plumbago indica Root Extracts

Kavita Mane, Rajendra Patil & Aditya Nath Pandey · Journal of Pharmaceutical Research International · 2021

Due to their well-known attribute of having minimal side effects as compared to medicines, natural items with medical potential are progressively gaining prominence in clinical research. The roots of Plumbago indica (P. indica, Plumbaginaceae) are commercially significant since t...

Open access Research Article 10.9734/jpri/2021/v33i53A33665

A Prospective Observational Study on Diabetic Induced Complications and their Prone towards Surgery

C. Madhusudhana Chetty, K. Mabichan, H. Raga Sandhya & K. Mallikarjuna · Journal of Pharmaceutical Research International · 2021

Background: This study was mainly aimed to find out the diabetic complications that had been lead to surgey. The Diabetes mellitus describes a metabolic disorder of multiple aetiology characterized by chronic hyperglycaemia with disturbances of carbohydrate,fat and protein metabo...

Open access Research Article 10.9734/jpri/2021/v33i53A33669

A Novel Synchronic Estimstion of Metronidazole, Ciprofloxacin and Doxycycline by RP-HPLC in Bulk and Pharmaceutical Formulation

Rama Rao Nadendla, Siva Prasad Morla, Abhinandana Patchala & Prachet Pinnamaneni · Journal of Pharmaceutical Research International · 2021

Aim: To design simple, rapid, new analytical method for estimation of Metronidazole, Ciprofloxacin Doxycycline by using RP-HPLC in bulk and pharmaceutical dosage form. Study Design: Estimation of Metronidazole, Ciprofloxacin Doxycycline by using RP-HPLC in bulk and pharmaceutical...

Open access Research Article 10.9734/jpri/2021/v33i53A33670

Barringtonia asiatica Seed Extract Induces G1 Cell Cycle Arrest in Saccharomyces cerevisiae and Exhibits Cytotoxicity in A2780 Human Ovarian Cancer Cells

Nilita Sirikit P. Villanueva, Carmela Vannette B. Vicera, Sheeny Fane L. Leonida, Melissa June Paderog, Edna M. Sabido, Jonel P. Saludes & Doralyn S. Dalisay · Journal of Pharmaceutical Research International · 2021

Barringtonia asiatica, is traditionally used as a medicinal plant in the Philippines; unfortunately, there is limited evidence supporting its anticancer capability. Thus, our study investigated the cytotoxic effect of B. asiatica seed extract against ovarian carcinoma A2780 (ECAC...

Open access Research Article 10.9734/jpri/2021/v33i53A33672

Frequency of Overweight Women and Ovarian Enlargement among Females Presented with Pelvic Pain Complains

Rukhsana Soomro, Zahida Parveen Brohi, Asma Jabeen, Afra Rehman & Mehreen Yousaf Rana · Journal of Pharmaceutical Research International · 2021

Objective: To determine the frequency of overweight females and ovarian enlargement among women presenting with pelvic pain complaints at rural Health facilities of district Tando Muhammad Khan. Methodology: This descriptive study was conducted at physiology department of Sindh U...

Open access Research Article 10.9734/jpri/2021/v33i53B33673

The Role of Ultrasound in Diagnosis of Acute Appendicitis: A Review Article

Rania Mohammed Ahmed · Journal of Pharmaceutical Research International · 2021

Acute appendicitis (AA) is a frequent abdominal infection that affects 7% of people at some time in their lives. As a result, any delay in diagnosis might lead to complications such as perforation and abscesses in the incision. Ultrasound (U/S) plays an essential role in the diag...

Open access Research Article 10.9734/jpri/2021/v33i53B33674

Role of Vitamin D in Reducing the Frequency of Asthma Attacks in Patients with Frequent Exacerbation of Asthma

Mubeen Ahmed Memon, Sheeba Faryal Ansari, Mumtaz Ali Lakho, Mukhtiar Hussain Jaffery, Syed Zulfiquar Ali Shah & Samar Raza · Journal of Pharmaceutical Research International · 2021

Introduction: Vitamin D deficiency is common among asthmatics with literature suggesting that its low levels in the body may trigger exacerbations and decrease the response to corticosteroid treatment. It has also shown to inhibit the production of cytokines, which in turn enhanc...

Open access Research Article 10.9734/jpri/2021/v33i53B33675

Phytochemicals against COVID -19, Pharmacological Perspectives: A Systematic Review

Ahmed S. Ali, Ekram A. Saied, Sharifa M. Theeban, Mazen M. Humayran, Assmaa Ahmed Shaker, Mohammed S. Almuhayawi & Abdelbagi Alfadil · Journal of Pharmaceutical Research International · 2021

Background: Many publications discussed the potential role of medicinal plants in the management of COVID-19. However, clinical studies of the efficacy and safety of specified phytochemical(s) are limited. Objectives: To explore the pharmacological profile of specified compounds...

Open access Research Article 10.9734/jpri/2021/v33i53B33678

Maternal Morbidity in a Context of Social Vulnerability: The Case of the Province of Essaouira, Morocco

Abdelmounaim Manoussi, Abdellatif Baali, Hakima Amor & Nadia Ouzennou · Journal of Pharmaceutical Research International · 2021

Aims: The main aim of this study is to assess the prevalence of maternal morbidity                         among childbearing women and to determine the associated factors in a context of social vulnerability. Study Design: This is a quantitative analytical cross-sectional study....

Open access Research Article 10.9734/jpri/2021/v33i53B33676

Determination of a Cone-Beam Computed Tomography based Assessment of Mental Foramen Position

Bashir Ahmed, Manoj Kumar, . Bushra, Suneel Kumar Punjabi, Raj Kumar & Salman Shams · Journal of Pharmaceutical Research International · 2021

Objective: To assess the occurrence and location of the mental foramen in relation to gender and age by using cone-beam computed tomography. Materials and Methods: A descriptive case series study was conducted at department of radiology at advance diagnostic care centre, Institut...

Open access Research Article 10.9734/jpri/2021/v33i53B33677

Rehabilitating Case of Tetralogy of Fallot Undergone Surgical Repair with Comprehensive Exercise Program: A Case Report

Sidra Ahmad Siraj, Vaishnavi Dilip Yadav, Moli Jai Jain & Om C. Wadhokar · Journal of Pharmaceutical Research International · 2021

Tetralogy of Fallot (TOF) is one of the most common cyanotic congenital heart disorders (CHDs). The children with CHD lead relatively sedentary lifestyles, on account of the restriction imposed by treating doctors, parents, and society and by themselves due to fear. The disabilit...

Open access Research Article 10.9734/jpri/2021/v33i53A33667

Braided Glass Fiber Reinforced Composite Resin Bridge - An Alternative Treatment for Management of Missing Anterior Tooth: A Case Report

Minal Soni, Jayashree Sajjanar, Jaykumar Gade, Anil Ingole, Karan Jaiswal & Arunkumar Sajjanar · Journal of Pharmaceutical Research International · 2021

Missing anterior teeth is of great concern during a patient's lifetime in many communities. A variety of treatment options, from implants to traditional bridges are often used in order to replace missing anterior tooth. However, it is often accompanied by variety of barriers such...

Open access Research Article 10.9734/jpri/2021/v33i53A33668