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A Systematic Review of Confounders Effecting on Sudden Infant Death Syndrome (SIDS)

Ayesha Noor, Areej Kainat, Ahmad Hanan Shah, Ahmad Safiyan, Hira Shahzadi, Iram Yousaf, Muhammad Jawad Akbar, Muhammad Humza Faran, Sana Iqbal, Eman Mustafa, Noor-e-Hizba Chaudhary, Abdulrehman Abid & Muhammad Zahid Iqbal · Journal of Pharmaceutical Research International · 2024

Sudden Infant Death Syndrome (SIDS) remains the leading cause of infant mortality, affecting countries worldwide, including both wealthy and developing nations. Many confounders are responsible for SIDS, which still can be avoided, and the prevalence can stop to save infant death...

Open access Research Article 10.9734/jpri/2024/v36i87554

Resistant Starch: Way to a Healthy Life

Sadhna Jain, Anamika Sinha, Ishita Rathi, Khyati Gupta, Neha Shishodiya, Shivangi Kukreti, Pratingya Rath & Alok Kumar · Journal of Pharmaceutical Research International · 2024

Prebiotic polysaccharides or resistant starches (RS) are the ones that are resistant to digestion. They are not digested by pancreatic amylase and hence do not hydrolyze D-glucose into the small intestine. One of the benefits of resistant starch is that it has a good impact on di...

Open access Research Article 10.9734/jpri/2024/v36i87555

Probiotics and its Application in Humans: An Overview

Arunavarsini K, Yuvansasi V, Sekar M, Durga Devi. L & Mahenthiran R · Journal of Pharmaceutical Research International · 2024

Probiotics are live microorganisms that have been identified as natural alternatives to antibiotics, which are typically used to treat bacterial infections causing many diseases in both humans and animals. It discusses the benefits and drawbacks of probiotics and presents evidenc...

Open access Research Article 10.9734/jpri/2024/v36i77552

An Improved Synthesis of Teriflunomide and Identification, Synthesis and Characterization of Its Critical Process Impurities

Panchabhai Prasad Pandurang & Kailas Narayan Sonune · Journal of Pharmaceutical Research International · 2024

Teriflunomide has an impeccable drug used to treat multiple sclerosis. Ample of literature is available for its synthesis, however, it does not reveals the potential impurities formation during synthesis, The chief intent of the article is to highlight the key impurities formatio...

Open access Research Article 10.9734/jpri/2024/v36i77551

Assessment of Diabetic and Inflammatory Markers in HIV Infected Adults with and without Diabetes Mellitus in NAUTH, Nnewi, Nigeria

Chidera Vivienne Obilo, Chukwuemeka Kingsley Obilo, Ofia Anya Kalu, Nkiru Chineye Nwoka, Chinenye Stellamaris Okeke, Ogalagu Romanus Ogai, Okezie Alozie Ogwuegbu, Chidinma Joy Iwuji, Chinonso Juliet Akaeme, Ezinne Gloria Ukibe, Blessing C Ukibe, Ezennia Victory Ukibe, Nancy Amarachukwu Mbachu & Nkiriuka Rose Ukibe · Journal of Pharmaceutical Research International · 2024

Background and Aim of Study: To assess the levels of fasting plasma glucose, insulin, insulin resistance, interleukin 10 (lL-10), high sensitive C - reactive protein (Hs-Crp) and tumour necrosis factor alpha (TNF-α) in HIV infected adult individuals with and without diabetes mell...

Open access Research Article 10.9734/jpri/2024/v36i77550

Behçet's Disease Current Therapies: MTX- Imuran and Long-term Effect of VIT D and Colchicine (Multi Centric Cohort Study from Aseer Region, Saudi Arabia)

Nouf A Alhammadi, Mushary S. Alqahtani, Khaled A. Amer, Abdullah AL Thawwab, Ahmed Saad Al Zomia, Hanan Alqahtani, Fares Ayed Alshahrani, Mohammed Abdullah Alshehri, Nasser Saidan Alaslai, Maram Ali AlShahrani, Raghad Saad Alshahrani, Arwa Ayed Alshahrani, Batool Abdullah Alahmary & Fahad Abdulruhman Alazragi · Journal of Pharmaceutical Research International · 2024

Background: Behçet's disease (BD) is a rare, chronic inflammatory disorder that recurs over time, impacting multiple systems, positioning it at the intersection of autoimmune and auto-inflammatory syndromes. BD is a unique clinical entity known for its diverse manifestations with...

Open access Research Article 10.9734/jpri/2024/v36i77548

Differential Scanning Calorimetry: A Powerful and Versatile Tool for Analyzing Proteins and Peptides

Akhilesh Kumar Kuril · Journal of Pharmaceutical Research International · 2024

Differential Scanning Calorimetry (DSC) is an efficient and versatile analytical technique widely used to study the thermal properties and stability of proteins. This review article provides a comprehensive overview of the principles and applications of DSC in protein research. D...

Open access Research Article 10.9734/jpri/2024/v36i77549

Influence of Age and Etching Technique on the Microleakage in Class-V Composite Restorations: An In-vitro Study

Kanwalpreet Kaur Bhullar, Aashish Handa, Surbhi Khurana & Sukhman Singh Sran · Journal of Pharmaceutical Research International · 2024

Aim: The objective of current research was to evaluate the impact of patient’s age on the microleakage in Class-V composite restorations. Study Design:  Research article. Methodology: 30 permanent human molars from various age groups (n=10 each) were collected. The teeth were cat...

Open access Research Article 10.9734/jpri/2024/v36i77546

Comparative Evaluation of Apical Microleakage in Root Canals Containing Separated Endodontic Files: An In vitro Study

Roohan Malhar Sandhu, Kanwalpreet Kaur Bhullar, Aashish Handa & Sukhman Singh Sran · Journal of Pharmaceutical Research International · 2024

Aims: The aim of the present in vitro study was to evaluate apical seal in the root canals containing separated instrument (Hand k files, Hyflex CM and Reciprocation Neoendo file) using dye penetration method. Study Design:  An In vitro study. Place and Duration of Study: Departm...

Open access Research Article 10.9734/jpri/2024/v36i77545

Detection of Metallo β-Lactamase in Acinetobacter Species Using Phenotypic Methods with their Antibiotic Resistance Profile in Tertiary Care Hospital

Manisha M. Rajguru, Deepashri Naik, Sareena Rao & Amit P Khekade · Journal of Pharmaceutical Research International · 2024

Background: Acinetobacter species are commonly found in nature, in water, and in soil, and also, and they have been isolated from humans and animals. In the hospital setting, Acinetobacter species has emerged as a major opportunistic pathogen, being able to colonize and develop i...

Open access Research Article 10.9734/jpri/2024/v36i77544

Formulation and Evaluation of Calendula and Lavender Oil Based Topical Antifungal Gel

Archi D, Pooja K & Shital F · Journal of Pharmaceutical Research International · 2024

Aim: Calendula officinalis and Lavendula angustifolia are traditional medicinal plants that have antifungal activity. A combination of these two plants has not been known for its activity against fungus. The present study deals with the formulation and evaluation of herbal topica...

Open access Research Article 10.9734/jpri/2024/v36i77543

Impact of Root Canal Treatment on Oral Health-related Quality of Life in European Population: A Systematic Review

Sara Shahid, Rabeel Khan, Areej Qamar, Arooj Nasir, Mahnoor Mahmood, Muhammad Tayyab, Ahmed Sabir, Muhammad Ahmed Khan, Areej Majeed, Maryam Ayesha & Muhammad Zahid Iqbal · Journal of Pharmaceutical Research International · 2024

Background: The current systematic review examines the complex picture of endodontic treatment, including quality of life, patient satisfaction, and caries prevalence, through 24 research studies conducted in various European countries. Methodology: A thorough and methodical sear...

Open access Research Article 10.9734/jpri/2024/v36i77542

Improved Topical Antifungal Medication using Sertaconazole Bilosomes: In vitro Permeability, Cytotoxicity, and Clinical Assessment

Omar Magdy Eldemiri, Germeen NS Girgis, Sara Hamdy Fouad & Thanaa Mohamed Borg · Journal of Pharmaceutical Research International · 2024

Objective: The purpose of the current study was to develop Sertaconazole bilosomes (SBs) with enhanced permeability, skin deposition, anti-fungal properties, and clinical efficacy. Methods: By changing span 60 to cholesterol molar ratio, bile salt type, and concentration, 12 form...

Open access Research Article 10.9734/jpri/2024/v36i77541

Observation of Travelling Ionospheric Disturbances over Morocco during the Godzilla Sand and Dust Storm of 15th to 26th June 2020 Using GNSS

Uluma Edward, Chali Idosa Uga, Solomon Otoo Lomotey, Athwart Davis Odhiambo, Fashae Joshua Bankole, Kouassi Nguessan, Muniafu Wilberforce, Boniface Ndinya & Omondi George · Journal of Pharmaceutical Research International · 2024

Using Vertical Total Electron Content (VTEC) data from four GNSS receiver stations: IFR1 (Ifrane Seismic), MELI (Melilla), TETN (Tetouan) and OUCA (Ouca) in Morocco, we investigate the Godzilla sand and dust storm (SDS) event of June 2020 as a source of energetics for generation...

Open access Research Article

Green Synthesis of Xanthenes: Utilizing Sulfonated Fructose as an Efficient and Eco-friendly Catalyst

Ali Kakeshpour, Ashraf Moradi & Farzaneh Moradi · Journal of Pharmaceutical Research International · 2024

The synthesis of xanthenes has garnered significant attention due to their extensive biological and therapeutic properties, including antibacterial, antiviral, and anti-inflammatory effects. Xanthenes are indispensable in organic synthesis and are also valued for their spectral p...

Open access Research Article 10.9734/jpri/2024/v36i77539