The most frequent pathogen linked to the development of UTIs is Uropathogenic Escherichia coli (UPEC). Thus, inhibiting the UPEC protein target (PDB ID 8BVD) would be a viable treatment approach. This study used molecular docking and dynamics to investigate Aloe barbadensis mille...
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Research Article10.9734/jpri/2024/v36i77540
Waad Abdulaziz Sabbagh, Hani Raka Karrar, Mahmoud Ismail Nouh, Nouran M. Alkhaifi, Samar Y. Badayyan, Lamer K. Shaikh, Nourah A. Al Ghamdi & Fai F. Abdullah·Journal of Pharmaceutical Research International·2024
Pneumonia is a major worldwide health issue, impacting millions of individuals annually and leading to a significant number of hospitalizations and fatalities. Pneumonia is the leading infectious cause of mortality in children globally, responsible for almost 15% of all fatalitie...
Open access
Research Article10.9734/jpri/2024/v36i77538
Green chemistry is the practice of creating chemical items and methods that diminish or totally dispose of the utilize or generation of unsafe compounds. This speaks to new, progressive advancement within the study of chemistry. The 12 directing standards for green chemistry were...
Open access
Research Article10.9734/jpri/2024/v36i77537
In terms of stability and quick reaction to external stimuli, nanogels are highly fa-voured materials in herbal medicine. In order to provide herbal products with greater cellular penetration than currently possible, nanogel is proving to be a novel approach to oral and transderm...
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Research Article10.9734/jpri/2024/v36i77536
Lana Lekić, Ervin Alibegović, Jasna Rahimić, Bojan Pavlović, Aida Hamzić-Mehmedbašić, Aldijana Mahmutović Milićević, Nehra Mosorović, Dino Alibegović & Emil Mujkić·Journal of Pharmaceutical Research International·2024
Antibiotics are medications that inhibit bacterial growth and are used in the treatment of bacterial infections, both gram-positive and gram-negative. Antibiotics also represent products of metabolism of certain microorganisms that adversely affect the development and reproductio...
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Research Article10.9734/jpri/2024/v36i77535
This study presents a novel and efficient method for synthesizing Tetrahydrobenzo[b]pyran and 3,4-Dihydropyrano[c]chromene derivatives using honey as a highly efficient homogeneous catalyst. Through a one-pot three-component condensation of aromatic aldehydes with malononitrile a...
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Research Article10.9734/jpri/2024/v36i77534
The complexity of the troposphere has a significant impact on radio signal transmission. This has led to the computation of refractivity gradients, which is an important parameter for the estimation of path clearance and propagation effects such as super-refraction, sub-refractio...
Aims: Solubility is a molecular property decisive in the entire process from drug development and design to the final drug formulation and production, the main objective of this paper is to explain the effect of the variance in molecular properties and intermolecular interaction...
Open access
Research Article10.9734/jpri/2024/v36i67532
Background: One of the main causes of morbidity is psychiatric disorders, which are becoming a burden to public health. The therapeutic choices are influenced by several factors, including treatment paradigms, safety, and costs that determine outcomes. Aim: We carried out the dru...
Open access
Research Article10.9734/jpri/2024/v36i77533
The topic and title concern the modern technology study and review with the aid and aiming the therapeutic interpretation and overall emphases on a novel corona virus disease called COVID-19, a respiratory disorder; to overcome the disease and its prevention, the article is deter...
Open access
Research Article10.9734/jpri/2024/v36i67530
Aims: To investigate the prevalence of work-related repetitive stress injuries amongst the healthcare professionals in large tertiary care hospital Materials & Methods: The study was conducted on 42 healthcare professionals (22 males and 20 females. The participants of the a...
Open access
Research Article10.9734/jpri/2024/v36i67531
Aravinth Velmurugan, Keerthana Chandramohan, Ganeshan Thamizhselvan, Yogesh Shokkalingam, Venkatesan Natarajan, Pradeepraj Devarasu & Thamizh Sendhamaraikannan·Journal of Pharmaceutical Research International·2024
Breast Cancer is a major health concern in India, where it is highly lethal for women because of unchecked cell proliferation and metastasis, which are frequently caused by interactions between the Estrogen Receptor Alpha and other receptors. Even though they work well, synthetic...
Open access
Research Article10.9734/jpri/2024/v36i67529
Celiac disease or gluten-sensitive enteropathy is an autoimmune hypersensitivity disorder affecting the small intestine. It occurs due to an inappropriate immune reaction to gluten, which results in inflammation and damage to the small intestine. One of the most prevalent illness...
Open access
Research Article10.9734/jpri/2024/v36i67528
Sara Shahid, Laiba Nadeem, Maria Faisal Khan, Wasta Aslam Gill, Minahil Nasir, Syed Taimoor Tayyab, Mavra Siddique, Maryam Ayesha & Muhammad Zahid Iqbal·Journal of Pharmaceutical Research International·2024
Background: Inhalation therapy is the main line of treatment for the management of various respiratory diseases due to localized delivery and rapid onset of action. Incorrect inhaler technique is very common and subsequently leads to poor disease management. Pharmacist can have a...
Open access
Research Article10.9734/jpri/2024/v36i67527
Introduction: Multidrug resistant tuberculosis (MDR-TB) is a global heath threat, resistant to key anti-TB drugs. It is ranked among the top 10 causes of death worldwide. Therefore, the current study investigated time to recovery from MDR-TB in southern Ethiopia. Data, Materials...
Open access
Research Article10.9734/jpri/2024/v36i67525