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All published articles 7450

A Comparison and Evaluation of Loop Diuretic Frusemide Generic vs Brand Tablets

Tamilveeran T, Karthikeyan B & Balamurugan K. · Journal of Pharmaceutical Research International · 2024

Branded medications are the original products developed by pharmaceutical companies and generic drugs are copies of branded drugs whose patent has expired. The research work focused on comparisons and evaluations of generic VS brand of frusemide tablets. The study includes some o...

Open access Research Article 10.9734/jpri/2024/v36i47509

In vitro Antioxidant, In vivo Bioavailability, and Immunomodulatory Effects of a Polyherbal Formulation (Storg B) Induced by Cyclophosphamide in an Experimental Animal Model

Firoz H M, Sadashiva C T & Sahana C V · Journal of Pharmaceutical Research International · 2024

Introduction: The immunomodulatory properties of plants are being extensively explored these days as they contain a wide range of bioactive compounds that can treat immunomodulatory disorders. The aim of the present investigation was to determine the efficacy of the standardized...

Open access Research Article 10.9734/jpri/2024/v36i47508

Correlation between Red Cell Distribution Width (RDW) and Mean Corpuscular Volume (MCV) as a Prognostic Biomarker for Diabetic Nephropathy Patients in a South Indian Hospital

A. Anandhasayanam, S. Kannan, H. Hemanandhini, R. Rajamurugan, R. Ranjith & S. Rajamani · Journal of Pharmaceutical Research International · 2024

Context: Diabetic nephropathy is one of the microvascular complications of diabetes mellitus, capable of leading to end-stage renal disease. Diabetic nephropathy could only be identified through renal biopsy testing, which is expensive and can impose a financial burden on patient...

Open access Research Article 10.9734/jpri/2024/v36i47507

Development and Assessment of Hydroxypropyl Methylcellulose-Based Floating Tablets for Ciprofloxacin HCL Using Direct Compression Technique

K. Venkata Gopaiah, J N Suresh Kumar, M. Ramya Teja, T. Lokesh, D. Sai Sruthi, M. Roja, N. Rushitha & SK. Vahedunnisa · Journal of Pharmaceutical Research International · 2024

The key findings and conclusions include: such as formulation approaches as aim and objective Development of floating tablets using sodium bicarbonate and HPMC aimed at enhancing gastric residence time for improved drug bioavailability. Physicochemical Compliances The formulated...

Open access Research Article 10.9734/jpri/2024/v36i37506

A Holistic Review of Rosacea and Its Association with Cardiovascular Diseases

Aymen Alharbi, Mohammed Abdullah Alahmadi, Sarah Mohammad Radwan, Abdulelah Nawaf Alraddadi, Esraa A. Shaheen & Roaa Abdulrahman Allehyani · Journal of Pharmaceutical Research International · 2024

Rosacea is a chronic inflammatory dermatological condition with different clinical phenotypes, usually diagnosed clinically and treated with systemic and topical medications. Rosacea is one of the skin conditions that is often believed to just have cutaneous manifestation, but it...

Open access Research Article 10.9734/jpri/2024/v36i37505

Extracts of Trichilia heudelotii (Meliaceae) Planch, a Nigerian Medicinal Plant have Antibacterial and Antifungal Activity

Adeniyi, B. A., Adagbasa, O. O., Idowu, P. A., Igbokwe, C. O., Moody, J. O. & Aiyelaagbe, O. O. · Journal of Pharmaceutical Research International · 2024

There is no overemphasizing the need for novel phytotherapeutic agents to combat the menace of drug resistance in microbial pathogens. Many plant species so far, have yielded some bioactive compounds with great promise for such drugs. Trichilia heudelotii (Meliaceae) is commonly...

Open access Research Article 10.9734/jpri/2024/v36i37504

Over-Expression of EFNA2 in Lung Adenocarcinoma: EFNA2 Gene Expression Correlates with Shortened Survival

Chunmei Liu, Yanjiao Wu, Huandi Zhou, Xiaohui Ge, Xiaojing Chang, Guohui Wang & Xiaoying Xue · Journal of Pharmaceutical Research International · 2024

Background: The incidence of lung adenocarcinoma (LUAD) is increasing worldwide with different prognosis. Ephrin-A2(EFNA2), a member of the Eph/ephrin family, is associated with tumor progression. However, the correlations of EFNA2 with prognosis in LUAD remain unclear. The   pu...

Open access Research Article 10.9734/jpri/2024/v36i37503

Randomized, Single Blind, Standard Controlled, Equivalence Clinical Trial to Evaluate the Comparative Efficacy of Eladi Kasaya Versus Tranexamic Acid Tablet in the Management of Asrigdara (Heavy Menstrual Bleeding): A Clinical Trial Protocol

Trapti Agrawal, Saunitra Inamdar, Hemanta Kumar Panigrahi & Pratiksha Rathod · Journal of Pharmaceutical Research International · 2024

Introduction: Excessive menstrual bleeding is a common problem in reproductive age group females, and it is reported that 1 in 20 lifetime chances, a female needs consulting the physician for excessive and prolonged menstrual bleeding. Ayurvedic literature describes excessive men...

Open access Research Article 10.9734/jpri/2024/v36i37502

Confounders Effecting Quality of Life of COPD Patients in European Union: A Systematic Review

Sara Shahid, Zuha Tariq, Obeda Asghar, Arooj Majeed, Umair Amjad, Wasiq Ali, Ahmad Sarfaraz, Muhammad Ahmed Saeed, M.Sohaib Sultan Sabri, Mohammad Abdullah, Azwa Zaheer, Muhammad Aamir, Talha Rehman, Asfa Iqbal & Muhammad Zahid Iqbal · Journal of Pharmaceutical Research International · 2024

Introduction: Chronic Obstructive Pulmonary Disease (COPD) is a respiratory disease characterized by restriction in expiratory airflow. It is among one of the major causes of illness and death globally. COPD causes severe negative effects on physical and mental health. It has a d...

Open access Research Article 10.9734/jpri/2024/v36i27501

Clinical Investigation of Valsartan Sustained-Release Matrix Tablets: Formulation Design and Performance Evaluation

Ramya Teja Medarametla, K. Venkata Gopaiah, J. N. Suresh Kumar, A. Kumar Sai, G. Mohana Chari, A. Kranti Kiran, B. Koteswarao Naik & K. Sandya Rani · Journal of Pharmaceutical Research International · 2024

The primary objective of this main study is to develop and assess the sustained-release matrix tablets containing Valsartan, an angiotensin II receptor type 1 antagonist. The powder mixtures underwent a thorough examination of pre-compression parameters and observed angle of repo...

Open access Research Article 10.9734/jpri/2024/v36i27500

Formulation Techniques, Characterization of Nanoemulsion and their Pharmaceutical Applications: A Comprehensive Technical Review

Muhammad Abid Mustafa, Namra Rasheed, Hamza Farooq, Muntaha Fazal, Emaan Asif, Hamna Shafiq, Muqadas Amin, Gohar Jaan, Amna Nadeem, Tooba Farooq, Neha Fatima, Sadia Ahmad & Muhammad Zahid Iqbal · Journal of Pharmaceutical Research International · 2024

Nanoemulsions are stable liquid-in-liquid dispersions with large surface areas, strong stability, optical transparency, and adaptable rheology. These submicron-sized emulsions are being studied for drug delivery and targeting in cosmetics, diagnostics, drug therapies, and biotech...

Open access Research Article 10.9734/jpri/2024/v36i27498

In silico Toxicity and Pharmaceutical Properties to Get Candidates for Antitumor Drug

Dewa Ayu Made Adnyaswari, Agung Wiwiek Indrayani & I. Gusti Ayu Artini · Journal of Pharmaceutical Research International · 2024

Background: Drug metabolism is a crucial aspect of medical practice and pharmacology, involving the transformation of drugs by various bodily systems to create compounds that are more easily eliminated from the body. Sorafenib was reported as a useful adjuvant treatment in patien...

Open access Research Article 10.9734/jpri/2024/v36i27497

Sonographic Measurement of the Liver in a Private Care Setting in Chattogram, Bangladesh

Istiaque Hossain & Shamsun Nahar B. Mannan · Journal of Pharmaceutical Research International · 2024

Introduction: The liver is one of the principal organs of our body involved in over 500 physiological functions related to metabolism, digestion, immunity, and storage of nutrients, which makes it an essential organ to preserve life. The aim of my study is to measure the differen...

Open access Research Article 10.9734/jpri/2024/v36i17496

Preliminary Phytochemical, Antioxidative and Antibacterial Screening of Selected Medicinal Plants for Possible use in the Treatment of Bacterial Diseases

Johnson V. Chibuzor, Felix A. Onyegbule, Blessing Umeokoli, Blessing O. Oyedemi & Eze I. Lucky · Journal of Pharmaceutical Research International · 2024

Development of cheap and reliable diagnostics is pivotal in the control of infectious diseases. Currently, one of the best strategies to tackle infectious disease is the use of natural products from plant origin, due to the perception that long term use of western medicine induce...

Open access Research Article 10.9734/jpri/2024/v36i17495