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All published articles 7450

Prevalence of Extraction of Primary Mandibular Second Molar in 3 to 5 Year Old Children

Rithanya. M & Ganesh Jeevanandan · Journal of Pharmaceutical Research International · 2024

Introduction: Tooth extraction is done based on a variety of reasons, the most common reason being the tooth becoming unrestorable as a result of dental caries, trauma to the tooth or periodontal disorder. The tooth indicated for extraction is usually associated with pain except...

Open access Research Article 10.9734/jpri/2024/v36i17494

Oxidative Stress and Diabetes Mellitus: Unravelling the Intricate Connection: A Comprehensive Review

Nadeem Rais, Akash Ved, Rizwan Ahmad & Aashna Parveen · Journal of Pharmaceutical Research International · 2024

Background: Diabetes mellitus (DM) is often associated with oxidative stress (OS), which is defined as an imbalance between the body's antioxidant defense systems and the generation of reactive oxygen species (ROS). OS serves as a crucial factor in the intricate relationship betw...

Open access Research Article 10.9734/jpri/2024/v36i17493

Gut Microbiome Derived Lactic Acid Bacteria (GM-d-LAB) from Dwarf Goats (Capra aegagrus hircus) Inhibit the Resident Multiple Antibiotics Resistance Bacterial pathogens

Bolanle Alake Adeniyi & Mercy Mayowa Olorunshola · Journal of Pharmaceutical Research International · 2024

Background: The global health threat posed by antimicrobial resistance (AMR) has created an urgent need for developing alternative treatment methods. Probiotics, especially Lactic Acid Bacteria (LAB), are gaining interest in this context, as they demonstrate health-enhancing effe...

Open access Research Article 10.9734/jpri/2024/v36i17492

Alpelisib Efficacy in Advanced Breast Cancer

Hani Raka Karrar, Mahmoud Ismail Nouh, Amnah Alhassan Alnami, Bashayr Eid Alrasheedi, Shuaa Rakan Alrwilli, Najwa Ahmed Hussain Durbashi, Lujain Badr Baghlaf, Ahmed Jamaan AlGhamdi, Zakaria Y. Otayn, Waad Fareed H Aowaiwi, Khalid Saad S Alghamdi, Alwaleed Oudah Hamdan Aljohani & Abdulrahman Saeed A Alzahrani · Journal of Pharmaceutical Research International · 2023

Breast cancer is one of the popular problems related to the medical field. Breast cancer become more aggressive, and the incidence rate keeps increasing yearly. The incidence indicates the slow progression of the disease. Yearly, there are more than one million new cases that get...

Open access Research Article 10.9734/jpri/2023/v35i357485

Saudi People’s Knowledge and Attitudes about Herbals’ Side Effects and their Interactions with Medications

Amal Sulaiman Alanazi · Journal of Pharmaceutical Research International · 2023

Introduction: The safety of herbal medicines is of particular importance because the majority of these products is self-prescribed and is used to treat minor and often chronic conditions. If not used with caution, some herbals may cause side effects and interactions with drugs. O...

Open access Research Article 10.9734/jpri/2023/v35i357486

Assessment of Health Care Providers Attitudes and Practices Concerning Medication Errors in Saudi Arabia

Shrooq Eid Alanzi · Journal of Pharmaceutical Research International · 2023

Introduction: Medication errors are one of the leading causes of patients’ morbidity and mortality in health care settings Objective: Assess awareness, attitude and practices of health care providers toward medication errors in Saudi Arabia. Methodology: Cross-sectional study des...

Open access Research Article 10.9734/jpri/2023/v35i367487

The Effectiveness of Modified Pilates Program with and without Kinesiotaping on Postnatal Urinary Stress Incontinence: A Randomized Clinical Trial

Radhika Chintamani · Journal of Pharmaceutical Research International · 2023

Introduction: Urinary Stress Incontinence is very common condition seen in postnatal woman. Without pelvic floor strengthening this condition will lead to social inhibition. The rate of urinary stress incontinence is more in normal vaginal delivery compared to C-Section. Few auth...

Open access Research Article 10.9734/jpri/2023/v35i367488

Assessment of Secondary Metabolites and Thin-Layer Chromatographic Analysis of Carica papaya (Caricaceae) Leaves Ethanolic Extract

Samuel J. Bunu, Joy O. Okei, Oyeintonbara Miediegha, Benjamin U. Ebeshi & Ogechukwu L. Chukwuemerie · Journal of Pharmaceutical Research International · 2023

Carica papaya, also referred to as pawpaw, is a tropical fruit-bearing tree in the Caricaceae family. Papaya is one of the world's most extensively grown crops. Its fruits, seeds, and leaves are widely utilized in cooking and traditional medicine. Papaya leaf extract, tea, and ju...

Open access Research Article 10.9734/jpri/2023/v35i367489

The Clinical Use of Anabolic Steroid Oxandrolone for Burn Patients: A Review

Lucas Caseri Câmara, Marcelo Andrade Starling & Erika Magalhães Suzigan · Journal of Pharmaceutical Research International · 2023

To reduce burn damage, especially in severe cases, pharmacological interventions aiming to decrease the intense catabolism such as the use of anabolic androgenic steroids (AAS) have been previously studied. Oxandrolone, an oral derived compound from DHT (dihydrotestosterone), is...

Open access Research Article 10.9734/jpri/2023/v35i367490

Evaluation of Requirement of Extraction of Maxillary Primary Canine in 3-5 Year Old Children

G. Nivedhita & Ganesh Jeevanandan · Journal of Pharmaceutical Research International · 2023

Dental extraction is the process of painlessly removing a whole tooth, or root, without majorly causing trauma to the adjacent tissues and tooth structure, so that the wound heals without causing any problem during postoperative prosthetic replacement. Primary teeth extraction is...

Open access Research Article 10.9734/jpri/2023/v35i367491

Prevalence of Dental Caries in Permanent Second Molars in Teenagers Using ICDAS

M. Rithanya & Mebin George Mathew · Journal of Pharmaceutical Research International · 2023

Introduction: Dental caries is a chronic disease of the tooth which is represented by demineralisation and destruction of the organic matter of the tooth. Dental caries are versatile, capable of affecting the crown portion of the tooth initially, and may affect the unprotected ro...

Open access Research Article 10.9734/jpri/2023/v35i357484

The Application of Response Surface Methodology (RSM) In the Computational Optimization of Sustained Release (SR) For Phenothiazine Derivative Matrix Tablet

Shiva Kant Thakur, Rahul Pal, Devanand Jha, Prottay Dutta, Prachi Pandey, Bhuneshwar Dutta Tripathi, Mohammad Rizwan, Shradha Ojha, Divya & Ravindra Pal Singh · Journal of Pharmaceutical Research International · 2023

Introduction: This study explores the use of Response Surface Methodology (RSM), a statistical optimization technique, to optimize the SR properties of prochlorperazine maleate (PCM) matrix tablets. PCM is a phenothiazine derivative used for treating schizophrenia, nausea, and vo...

Open access Research Article 10.9734/jpri/2023/v35i357483

Acute Oral Toxicity and Antispasmodic Effects of Two Extracts of Diospyros mespiliformis Hochst. Ex A. DC. (Ebenaceae) Immature Fruits on the Isolated Rat Duodenum

Mathieu Nitiéma, Lazare Belemnaba, Boukaré Kaboré, Pegdwendé Esther Ouédraogo, Windingoudi Rimwagna Christian Ouedraogo, Oumarou Maman Noura, Wendkouni Leila Marie Esther Belem-Kabré, Tata Kadiatou Traoré, Souleymane Compaoré, Moumouni Koala, Bruno Nébié, Noufou Ouedraogo & Sylvin Ouédraogo · Journal of Pharmaceutical Research International · 2023

Aims: Our study aimed to evaluate the chemical profile, the antioxidant and anti-inflammatory activities, the spasmolytic effects, and the safety of use of hydroethanolic extract (HE_FDM) and aqueous macerate extract (AM_FDM) of Diospyros mespiliformis immature fruits. Place and...

Open access Research Article 10.9734/jpri/2023/v35i347479

Enhancing Awareness of Diclofenac as an Over-the-Counter Analgesic in the Northern Border Region of Saudi Arabia

Seham Zaid Alshammari · Journal of Pharmaceutical Research International · 2023

Introduction: Diclofenac was identified by the Pharmacovigilance Risk Assessment Committee of the European Medicines Agency as a high-risk NSAID in terms of its effects on the heart and circulation when administered systemically, i.e. capsules, tablets or injections. Objective: T...

Open access Research Article 10.9734/jpri/2023/v35i347480