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Diosgenin Nanoparticles Competes Plain Diosgenin on Reviving Biochemical and Histopathological Alterations in DMBA Induced Rat Mammary Carcinoma via Modulating the AhR-Nrf-2 Signaling Cascades

Manobharathi Vengaimaran, Kalaiyarasi Dhamodharan & Mirunalini Sankaran · Journal of Pharmaceutical Research International · 2021

Background: Diosgenin, a steroidal saponin spotted as a primary ingredient in many traditional Chinese medicines, has sparked the attention of researchers owing to its multi-targeted cytotoxicity towards a multitude of cancers. Regrettably, its true potential was bounded by its i...

Open access Research Article 10.9734/jpri/2021/v33i47A32998

A Mini-Review: Nanoparticles as Vaccine Delivery System

Frial G. Abd, Lubna Abdulazeem, Saade Abdalkareem Jasim, Ahamed H. Rasheed & Sumaya Ayad Abdulrazzaq · Journal of Pharmaceutical Research International · 2021

Vaccination has proven to be one of the most important medical breakthroughs in history. Three important features must be present in every vaccine that is effective over time: Safety, stability, and the ability to elicit a sustained and sufficient immune response with a modest nu...

Open access Research Article 10.9734/jpri/2021/v33i47A33004

A Study to Assess the Effectiveness of Progressive Muscle Relaxation Technique among the Patient with Anxiety Disorders in the Selected Mental Health Centers

A. R. Bharathi · Journal of Pharmaceutical Research International · 2021

Nowadays, major impact of researchers’ toevaluate the intensity of anxiety between Anxiety Disorder with the Patient, and theirefficacy of enlightened muscle relaxation and disorder of anxiety to the patients, intensity of anxiety amongst mental health center describe the anxiety...

Open access Research Article 10.9734/jpri/2021/v33i47A32999

Overview on Cardiac Cirrhosis and Congestive Hepatopathy - A Review

Mohammed Salah Hussein, Sarah Jamal Almujil, Ahmed Saeed S. Banheem, Nasser Naif Alsuhaymi, Mansour Hemaid Alhelali, Dhiyaa Hassan A. Aldukhi, Khalil Rafed B. Alsaedi, Naif Mohammed Al-Wagdani, Ebtesam Ali S. Almadi, Khalid Mohammed A. Aladhadh & Fahad A. M. R. H. AlAjmi · Journal of Pharmaceutical Research International · 2021

Cardiac cirrhosis (congestive hepatopathy) refers to a group of hepatic abnormalities that develop as a result of right-sided heart failure.  Cirrhosis of the liver can be induced by any right-sided pathology that leads to right-sided heart failure, which leads to increased venou...

Open access Research Article 10.9734/jpri/2021/v33i47A33006

Anti Ulceration Efficacy of Boiled Aqueous Leaf Extract of Morinda lucida on Ethanol Induced Gastric Ulceration Rats

Nkiruka Millicent Amadi, Peter Uwadiegwu Achukwu, S. O. Onwukwe, Emmanuel I. Obeagu, Nonyelum V. Anoh & Victoria I. Okpokwu · Journal of Pharmaceutical Research International · 2021

Stomach ulceration study was carried on 25 groups (5 rats each of the groups), groups (E, E1, E2, , E3 and EC, placed on 24 hours fasting before the single dose of intra peritoneal dose administration of 5ml/kg body weight of 99% ethanol and  after one hour, received daily extrac...

Open access Research Article 10.9734/jpri/2021/v33i47A33000

FTIR and XRD of Zinc Oxide Nano Particle from Mangifera indica L. anacardiaceae

S. Udhaya Geetha & S. Thilakavathy · Journal of Pharmaceutical Research International · 2021

Zinc Oxide nanoparticle (ZnO) is broadly used in food packaging industry. Synthesis of ZnO includes different methods like using chemical, gas and sol gel. But it contains more toxins. Hence biosynthesis of zinc oxide nanoparticle is eco-friendly and non toxic. It acts as an anti...

Open access Research Article 10.9734/jpri/2021/v33i47A33001

Correlation of the Protein Expression of Salivary Cortisol, Serum Vitamin B12 and Interleukin 1 Beta in Patients with Recurrent Aphthous Stomatitis

R. Deepa Viswasini, Pratibha Ramani & J. Selvaraj · Journal of Pharmaceutical Research International · 2021

This study will help in determining which molecules participate in the ulceration with an integrated approach combining external and internal factors. Recurrent aphthous stomatitis (RAS) is a common condition affecting the oral mucosa. Clinically it is manifested through recurren...

Open access Research Article 10.9734/jpri/2021/v33i47A33003

Evaluation of Patient-Oriented Medicines Supply Information on Russian Healthcare Providers’ Websites

Nikita V. Polukhin, Natalia V. Ekkert & Mikhail V. Vodolagin · Journal of Pharmaceutical Research International · 2021

Aims: To evaluate the Russian Federation healthcare providers’ websites compliance to legal requirements on availability of patient-oriented medicines supply information and compare the evaluation results between public and private healthcare facilities. Study Design: Cross-secti...

Open access Research Article 10.9734/jpri/2021/v33i47A33005

COVID -19 in Geriatric Population

Pratiksha S. Thakare, Samruddhi Gujar, Shakib Sheikh & Vrushali Dighikar · Journal of Pharmaceutical Research International · 2021

The causative factors of Coronavirus disease mainly the viruses. Through news we aware that pneumonia cases seen recently in Wuhan city, China. Due to unknown causes. Coronaviruses that cause illness such as a common cold. The Coronavirus infection identified with respiratory sym...

Open access Research Article 10.9734/jpri/2021/v33i46B32967

Prevalence of Nutritional Anemia and Its Causes among Adolescent Girls

Sonal Dhobe & Seema Singh · Journal of Pharmaceutical Research International · 2021

Background: Nutritional anemia is a disorder that cause due to a lack of one or more vital nutrients, such as iron, protein, vitamin B12, and other vitamins and minerals. In this condition hemoglobin content in the blood is lower than usual. Nutritional anemia has been described...

Open access Research Article 10.9734/jpri/2021/v33i46B32965

A Case Report of Complete Heart Block

Sonal Dhobe, Seema Singh, Ranjana Sharma & Ruchira Ankar · Journal of Pharmaceutical Research International · 2021

Introduction: Complete Heart Block (CHB) occurs when the electrical signals can’t pass normally from the atria, the heart’s upper chambers, to the ventricles or lower chambers. This condition can develop because of congenital or secondary to cancers, myopathies or heart ischemia,...

Open access Research Article 10.9734/jpri/2021/v33i46B32974

Case Report on ANC Mother Two Month with Severe Anemia

Roshani Shankarrao Warghane, Kavita Gomase & Manjusha Mahakarkar · Journal of Pharmaceutical Research International · 2021

Introduction: Human body creates extra blood throughout pregnancy to support human baby's growth. If you don't get enough iron or certain other nutrients, human body may be unable to manufacture the necessary number of red blood cells to produce this extra blood. When you're preg...

Open access Research Article 10.9734/jpri/2021/v33i46B32975

Review on Medicinal Properties of Jatropha gossypiifolia L.

Milind S. Pande, Neelanchal Trivedi & Bhuvnesh Kumar · Journal of Pharmaceutical Research International · 2021

Jatropha gossypiifolia L. broadly addressed as bellyache bush, refers to therapeutic plant utilized all through Asian countries. A few human and veterinary utilizations in conventional medication are portrayed for various specifics and arrangements dependent on aforementioned pla...

Open access Research Article 10.9734/jpri/2021/v33i46B32968

Airway Management in COVID- 19 Patients

Sonal Dhobe, Ruchira Ankar, Roshani Dhanvijay, Vrushali Dighikar & Pratiksha Thakre · Journal of Pharmaceutical Research International · 2021

The first case found in 31 December 2019 in China, in Wuhan city but China reported this news to WHO in January 2020 after this corona virus can spread worldwide, and WHO declare this disease as a pandemic. As per survey now over the 4,444,670 cases of Covid-19 can identified in...

Open access Research Article 10.9734/jpri/2021/v33i46B32977

Overview on Regulatory Requirements for Medical Devices in Srilanka - National Medicines Regulatory Authority/NMRA

Vishakharaju Motupalli, Subhash Chandra Bose, M. P. Venkatesh, Varsha Tiwari & Gembali Ramya · Journal of Pharmaceutical Research International · 2021

In the health-care industry, medical devices are becoming increasingly significant. One of the most challenging aspects of developing and manufacturing medical devices is keeping up with regulatory regulations and incorporating them into the process Registration, licensing, manuf...

Open access Research Article 10.9734/jpri/2021/v33i46B32978