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All published articles 7450

Compound Characterization and Evaluation of Antioxidant Potential of Ethanol Extract Spatholobus littoralis Hassk in Kolaka, Southeast Sulawesi, Indonesia

Ruslin Hadanu, Irwansyah, Sartika G. P. & Retno Wahyuningrum · Journal of Pharmaceutical Research International · 2023

The bajakah tampala plant (Spahtolobus littoralis Hassk) has been traditionally believed by the public to cure cancer, tumors, heart disease, stroke, and diabetes. However, empirically the public does not yet know the chemical compound content and there have been no studies on bi...

Open access Research Article 10.9734/jpri/2023/v35i287450

Gastric Ulcer Mechanism, Protection and Treatment from Natural Sources

Shiv Kumar, Arushi, Vijay Sharma & Manjula Devi · Journal of Pharmaceutical Research International · 2023

Gastric acid secretions are main cause for formation of gastric ulcers that are attributed by Helicobacter pylori infection and extensive use of NSAIDs (non-steroidal anti-inflammatory drugs). These contributors facilitate the initiation of cellular and molecular signalling pathw...

Open access Research Article 10.9734/jpri/2023/v35i287449

Healthcare Professionals' Knowledge, Attitude and Perception toward Adverse Drug Reaction Reporting in Saudi Arabia: A Systematic Review

Hana Jaffar Al Khabbaz · Journal of Pharmaceutical Research International · 2023

Aims: To systematically evaluate the currently available evidences about the knowledge, attitude and perceptions of healthcare professionals in Saudi Arabia towards reporting adverse drug reactions to the Saudi Food and Drug Authority (Saudi FDA) as the regulatory authority monit...

Open access Research Article 10.9734/jpri/2023/v35i287448

Evaluation of Potential Drug-drug Interactions in Prescription in Outpatient Department of Tertiary Care Hospital

Sunil M. Mahakalkar, Akhil Giradkar, Rahul Gholse, Umesh Rathod & Divya Raj · Journal of Pharmaceutical Research International · 2023

Aims: To evaluate potential drug- drug interactions (pDDIs) in prescriptions generated in outpatient department. Study Design:  A cross sectional, observational study. Place and Duration of Study: Pharmacy store, Government Medical College & Hospital, Nagpur, between July 202...

Open access Research Article 10.9734/jpri/2023/v35i287447

Molecular Modeling of Enoyl Acyl Carrier Protein Reductase Inhibitors for Mycobacterium tuberculosis and their Pharmacokinetic Predictions

Narcisse Fidèle Zonon, Logbo Mathias Mousse, Koffi N’Guessan Placide Gabin Allangba, Koffi Charles Kouman & Eugene Megnassan · Journal of Pharmaceutical Research International · 2023

Tuberculosis (TB) is a deep public health concern worldwide worsened by reported multi drugresistant (MDR) and extensively drug- resistant (XDR) stralins of Mycobacterium tuberculosis, the causative agent of the disease. A new class of thiadiazole inhibitors were reported to inhi...

Open access Research Article 10.9734/jpri/2023/v35i287446

Intravenous Hyoscine Butylbromide “Scopolamine” for the Treatment of Extrapyramidal Symptoms: A Case Report

Alanazi Saleh Farhan M. · Journal of Pharmaceutical Research International · 2023

Aim: Extrapyramidal symptoms (EPS) represent motor disturbances frequently induced by medications that impact the dopamine pathways. Although not traditionally employed for addressing EPS, there is potential in using hyoscine butylbromide, an anticholinergic antispasmodic, owing...

Open access Research Article 10.9734/jpri/2023/v35i277445

Knowing the Unknown: A Review on Nanotechnology in Orthodontics

Ali Fathima S., Abiraj K. R., Pratheesh A. P., Sonu M. Mohan, Krishna A. S. & Dynamol S. · Journal of Pharmaceutical Research International · 2023

Nanotechnology is the structuring and manipulation of matter at nanoscale for the creation of new particles and devices. The applications of nanotechnology are being explored in various arenas including health care. The use of this technology aims to improvise the quality of heal...

Open access Research Article 10.9734/jpri/2023/v35i277443

The Effect of Tannic Acid as Antimicrobial Agent on Pseudomonas aeruginosa Using In-vitro Diffusion Method

Sardjiman, Rolando Rahardjoputro & Joko Santoso · Journal of Pharmaceutical Research International · 2023

Background: Bacterial infection is a health problem that has long been attention in the world of health. Various antimicrobials have been discovered and developed by researchers to solve pathogenic bacterial infections. Pseudomonas aeruginosa is a pathogenic bacteria that is ofte...

Open access Research Article 10.9734/jpri/2023/v35i277442

Simultaneous Analysis of Trace Tetracyclines Antibiotics in Wastewater with Ultra-high Performance Liquid Chromatography Coupled with Mass Spectrometry

Hua Wang · Journal of Pharmaceutical Research International · 2023

A comprehensive method was developed for determination of tetracycline, oxytetracycline, chlortetracycline, and doxycycline in wastewater. Based on ultra-high performance liquid chromatography coupled with mass spectrometry (UHPLC–MS), the developed method was specific, sensitive...

Open access Research Article 10.9734/jpri/2023/v35i277441

The Chinese-Han Population Carrying Wild-type Genotypes of SLCO1B1 388A>G, SLCO1B1 521T>C, CYP3A4 1B, CYP3A4 1G, and CYP3A5*3 Exhibits a Significant Alteration in the Pharmacokinetics of Atorvastatin Calcium

Binbin Xia, Xianjun Liu, Yali Li, Yang Liu, Wenfang Sun, Jing Chen, Liushui Li, Jingyao Pang, Shicai Chen & Hua Cheng · Journal of Pharmaceutical Research International · 2023

Due to the diverse genetic characteristics of metabolism and high drug plasma exposure, great inter-subject variability exists in the clinical efficacy and incidence of adverse events. This study aimed to evaluate the associations between the SLCO1B1 388A>G (rs2306283) polymorph...

Open access Research Article 10.9734/jpri/2023/v35i277440

A Cross-sectional Study to Assess Pandu Vyadhi (Anemia) with Special Reference to RBC Indices and Morphology: A Study Protocol

Seema H. Thakare & Umesh Patil · Journal of Pharmaceutical Research International · 2023

Background: Ayurveda is a science of life & its holistic approach towards Dietary habits, seasonal regimes, daily regimes, lifestyle practices helps to maintain health of an individual. Inadequate dietary intake or lack of balanced diet leads to malnutrition & has major r...

Open access Research Article 10.9734/jpri/2023/v35i267439

Pushkarmoola (Inula racemosa Hook. F.): A Healing Legacy Unveiled - Exploring its Potent Anti-Pyretic and Medicinal Significance

Anju K. l., Vaibhav Jaisawal, Sanjeev Kumar, Kiran Vashishtha & Anurag Mishra · Journal of Pharmaceutical Research International · 2023

Pushkarmoola, scientifically known as Inula racemosa Hook. F., is a robust herb belonging to the Asteraceae family. It is renowned for its potent medicinal properties, particularly in the realm of cardio-pulmonary health. In contemporary times, it enjoys significant recognition a...

Open access Research Article 10.9734/jpri/2023/v35i267438

Medical Students' Perception of Colors Influence on the Learning Process

Syed Sajid Hussain Shah, Asmara Syed, Amin Khalid Makhdoom, Dhari Atallah Alshammari & Saima Syed · Journal of Pharmaceutical Research International · 2023

  Background: Human being are affected by the surrounding environment. One of the component of the environment is presence of various colors. Different colors exert different impact on human psychology and the state of human psychology affects the learning process.    Aims: We ai...

Open access Research Article 10.9734/jpri/2023/v35i267437

345 Years of the Master Degree of Edmond Halley and the Trajectories of Five Comets after the Passage of the Halley Comet in 1986: A Didactical and Historical Approach

Marcos Cesar Danhoni Neves, Daniel Gardelli, Josie A. P. Silva, Ricardo Francisco Pereira, Wilson Guerra & Ana Claudia D. Neves · Journal of Pharmaceutical Research International · 2023

This paper presents a historical approach of Edmond Halley and the discovery of the comet that would be known as comet Halley. It will be presented a development of a geometrical method, based upon the second Kepler’s Law, to calculate the trajectories of five comets: Halley, Hal...

Open access Research Article

Dimension of Psycho-social Distress and Associated-complications in Type 2 Diabetes Population

Amala Joseph, Aiswarya Thomas, Jilbi Josey & Rosmin Jacob · Journal of Pharmaceutical Research International · 2023

Aim: This study analyzes the psycho-social challenges and problems experienced by individuals diagnosed with type 2 diabetes, utilizing the diabetes distress scale (DDS). Moreover, this research offers patients recommendations and guidance to enhance their overall well-being and...

Open access Research Article 10.9734/jpri/2023/v35i267436