Skip to content

All published articles 7450

Anti-Cancer Activity of Andrographolide: A Review

Vishwanadham Yerragunta, Kavita Waghray, . Shivraj & N. J. P. Subhashini · Journal of Pharmaceutical Research International · 2021

Andrographolide, is a chemical compound obtained from the Andrographis paniculata (Family- Acanthaceae), maybe a diterpene lactone ring is responsible for various biological activities like anti-inflammation, anti-microbial anti-cancer, anti-obesity, anti-diabetes, anti-oxidant i...

Open access Research Article 10.9734/jpri/2021/v33i43B32519

Rudimentary Pharmacological Inspection of the Ethanolic Extract of Grewia hirsute Vhal

Mst Marium Begum, Mohammad Abdul Alim, Md. Razu Ahmed, Abdullah Al Mamun, Munny Das, Rayhana Begum, Azharul Islam, Md. Marufur Rahman Moni, Sumiya Alam, Wahida Akter & Md. Sohanur Rahman · Journal of Pharmaceutical Research International · 2021

Background: Screening of plant kingdom for various pharmacologic activities with an aim of discovering new active constituents is a continuous process and a part of systemic analysis. Purpose: The purpose of this study was to investigate hypoglycemic, hypolipidemic, anti-ulcer, a...

Open access Research Article 10.9734/jpri/2021/v33i43B32520

Compare the Effect of Oral Pregabalin versus Oral Clonidine for Attenuation of Hemodynamic Responses for Laryngoscopy and Tracheal Intubation

J. Devanand · Journal of Pharmaceutical Research International · 2021

This study was done to assess the laryngoscopy and intubation responses of two drugs namely, Pregabalin 150mg and Clonidine 0.2mg. The drugs were orally administered 90 minutes prior to induction, as the peak action of both the drugs are known to be 1-2 hours after oral administr...

Open access Research Article 10.9734/jpri/2021/v33i43B32521

Structural Characterization, Antimicrobial and Antioxidant Assay of Biogenically Synthesized Maghemite (γ-Fe2O3) Nanoparticles

A. Leema Rose, B. Shabushree & Preeja P. Thattil · Journal of Pharmaceutical Research International · 2021

Aims: The present study focused on the optical and morphological characterization, antioxidant and antimicrobial activities of the biogenically synthesized iron oxide nanoparticles.  Methods: The preliminary phytochemical screening was done for the leaf extract of Annona reticula...

Open access Research Article 10.9734/jpri/2021/v33i43B32522

The Perspective of General Practitioners about Mental Illness: A Cross-sectional Observational Study from a Tertiary Care Centre, Pakistan

Muhammad Iqbal Afridi, Jawed Akbar Dars, Chooni Lal, Rakesh Kumar, . Sadia, Ali Bux Rajper & Ubedullah Shaikh · Journal of Pharmaceutical Research International · 2021

Objectives: To assess the general practitioner's perspective on mental illness in a tertiary health care setting. Study Setting and Duration: Online seminar in March 2020, Jinnah Postgraduate Medical Centre, Karachi. Study Design: Cross-sectional, Observational study Methodology:...

Open access Research Article 10.9734/jpri/2021/v33i43B32523

Evaluation of Effectiveness of Chronic Care Model on Smokeless Tobacco Cessation by Measuring Urinary Cotinine Level among the Patient Attended in the Selected Dental College & Hospital, India -An Experimental Study

Sakshi Rao, Pooja Raut, Riya Agrawal, Kumar Gaurav Chhabra, Priyanka Paul Madhu & Amit Reche · Journal of Pharmaceutical Research International · 2021

Background: Smokeless tobacco is one of the most common causes of preventable death. It is a big social and health issue. Smokeless tobacco utilization is a significant cause of morbidity and mortality in India, with more than 20% of the world's tobacco-related mortality occurrin...

Open access Research Article 10.9734/jpri/2021/v33i43A32510

Occurrence of Hemorrhoids and Anal Fissures through Pregnancy and Postpartum

Esmatullah (Esmat) & Baseera (Esmat) · Journal of Pharmaceutical Research International · 2021

Objective: To recognize occurrence also danger issues of hemorrhoids and fissures throughout pregnancy and afterwards childbirth. Population: The overall 180 pregnant females trailed up till 1 month after delivery. Methods: Females remained inspected 4 times via pregnancy and aft...

Open access Research Article 10.9734/jpri/2021/v33i43A32497

Effects of Proton Pump Inhibitors on Serum Calcium Level: A Study on Rabbit Model

Rizwan Ahmed Memon, Fazeela Rizwan Memon, Ali Raza Memon, Jamshaid Ul Qadir Memon, Jawaid Hussain Laghari, Salman Shams & Ashfaq Rahim Memon · Journal of Pharmaceutical Research International · 2021

Background: Proton Pump inhibitors (PPI) are widely used all over the world as therapeutic agents as well as prophylactic agent at different age groups for multiple gastrointestinal disorders etc. it inhibits the hydrogen potassium pump (H/K ATPase Pump). PPI interferes the calci...

Open access Research Article 10.9734/jpri/2021/v33i43A32498

In-silico Inhibitory Potential of Triphala Constituents Against Cytochrome P450 2E1 for the Prevention of Thioacetamide-induced Hepatotoxicity

Aziz Unnisa, Sharuk L. Khan, Farooque A. H. Sheikh, Syed Mahefooz, A. A. Kazi, Falak A. Siddiqui, Nitin Gawai & Shweta G. Saboo · Journal of Pharmaceutical Research International · 2021

Background: Triphala, which is a combination of fruits of Terminalia chebula, Terminalia bellerica and Embilica officinalis generally recommended as herbal drug formulation in the Indian traditional medicine system. Study Design: To study the in-silico inhibitory potential of Tri...

Open access Research Article 10.9734/jpri/2021/v33i43A32499

Gender-Based Assessment of Haematological Parameters of Obese Individuals in Omisanjana Area of Ado Ekiti, Ekiti State, Nigeria

Emmanuel I. Obeagu, Precious Omotunde, Getrude Uzoma Obeagu, Richard I. Eze, Ukamaka Edward, Chukwum J. Okafor, C. C. N. Vincent, Ejike Felix Chukwurah & Blessing Oluchi Akalonu · Journal of Pharmaceutical Research International · 2021

Background: Obesity is a serious health problem, it increases heart-related diseases and its prevalence continues to increase due to genetic and lifestyle influences. This study aims to evaluate the hematological parameters of obese individuals based on gender in the Omisanjana r...

Open access Research Article 10.9734/jpri/2021/v33i43A32500

Nutritional Awareness and Weight Status of Nursing College Students during COVID 19 Lockdown

K. Silambu Selvi, C. Kanniammal, B. Jayabharathi & E. Lakshmi · Journal of Pharmaceutical Research International · 2021

Aim: The present study aim was to assess the BMI status and level of nutrition knowledge among nursing college students during covid19 lockdown Methods: This cross sectional survey was carried out during covid19 lockdown period in Tamil Nadu among 247 nursing college students .Th...

Open access Research Article 10.9734/jpri/2021/v33i43A32501

Evaluation of Anti-oxidant and Anti-pyretic Activity of Leaf of Dendrobium chrysanthum

Mrinmoy Basak, Pal Gogoi, Sajidul Hoque Ansari, Biplab Kumar Dey, Saikat Sen & Moksood Ahmed Laskar · Journal of Pharmaceutical Research International · 2021

This investigation is based on a very remarkable and interesting orchid of the genus Dendrobium widely available in Meghalaya (India) and it is the world second largest orchid genus. The purpose of the study was to evaluate the anti-oxidant and anti-pyretic activity of leaf of De...

Open access Research Article 10.9734/jpri/2021/v33i43A32502

Antibiotics Using Pattern in Surgery Department of a Maternity and Children Hospital

Nehad J. Ahmed & Abdulrahman G. Alharbi · Journal of Pharmaceutical Research International · 2021

Aim: This study aimed to identify antibiotics using pattern in surgery department of a maternity and children hospital in Alkharj. Methodology: This is a retrospective review of the drugs that were prescribed in maternity and children hospital in Alkharj from January 2018 to Augu...

Open access Research Article 10.9734/jpri/2021/v33i43A32503

Screening of Zinc Database against Streptococcal Cysteine Protease Enzyme for Identification of Novel Group A Streptococcus Inhibitors

Ratul Bhowmik, Ranajit Nath & Ratna Roy · Journal of Pharmaceutical Research International · 2021

Inhibition of streptococcal cysteine protease has recently emerged as quite a promising target to treat severe cases of Group A Streptococcus infections. For the identification of streptococcal cysteine protease inhibitors, structure-based virtual screening (SBVS) of the ZINC Dat...

Open access Research Article 10.9734/jpri/2021/v33i43A32504