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All published articles 7450

The Efficacy of Pelvic Floor Exercise for the Stress Urinary Incontinence

Pradnya Gavhale & Manjusha Mahakarkar · Journal of Pharmaceutical Research International · 2021

Background: Stress urinary incontinence is an involuntary leaking of urine during physical activity, such as coughing, sneezing, laughing, or exercise that increases abdominal pressure. Stress urinaryincontinence has a wide variety of impacts on women's daily. Objectives: To asse...

Open access Research Article 10.9734/jpri/2021/v33i43A32469

Current Status and Perspectives of Oral Therapeutic Protein and Peptide Formulations: A Review

G. Manu, Nagma Firdose, M. K. Jayanthi, Ramith Ramu, Ranjith Raj, Shashank M. Patil, S. Jagadeep Chandra & Prithvi S. Shirahatti · Journal of Pharmaceutical Research International · 2021

Medicinal formulations have evolved from the use of small molecules that act by blocking various receptors. On the contrary, therapeutic proteins are a class of medicines that have gained increased popularity owing to its low toxicity, high stability and exquisite specificity. Or...

Open access Research Article 10.9734/jpri/2021/v33i43A32472

Association between Chronotype and Type 2 Diabetes: A Literature Review

Samir Barve, Sonopant Joshi & Abhay Saraf · Journal of Pharmaceutical Research International · 2021

Chronotype is an individual attribute of a person regarding circadian rhythm. Past literature denotes that the evening chronotype individuals are more prone to obesity, sleep problems, unhealthy diet and lifestyles. This review investigates original research studies on associatio...

Open access Research Article 10.9734/jpri/2021/v33i43A32475

The Situation and Preventive Measures Related to COVID-19 Infection for Medical Staff

Abdul Ghafar Sherzad, Yan Tu, Weitao Liu, M. Azim Azimee, Arash Nemat, Abdullah Asady, Nahid Raufi, Ying Huang, Xingbo Xu, Osama Alsarhan & Qingchun Zeng · Journal of Pharmaceutical Research International · 2021

The novel coronavirus, or COVID-19, emerged from Wuhan, Hubei Province, China, and has recently spread all over the world. During the COVID-19 pandemic, healthcare workers struggle against this microscopic enemy due to their job responsibilities, thus leading to be infected in so...

Open access Research Article 10.9734/jpri/2021/v33i43A32477

Study of Lipid per Oxidation and Enzymatic Antioxidant Activity in Rheumatoid Arthritis: Relation with Disease Activity

Dipali Khopade, Anita Kadam, Subodhini Abhang & Adinath Suryakar · Journal of Pharmaceutical Research International · 2021

Background: Rheumatoid Arthritis (RA) is one of the known Autoimmune diseases in patients with age group of 25 to 60. A significant aspect of disease development should be Reactive Oxygen Species (ROS). Few studies have shown an association between oxidative stress and RA disease...

Open access Research Article 10.9734/jpri/2021/v33i43A32464

Clinical, Hematological and Immunological Correlation in Children with Dengue Infection

Bratati S. Mishra, Nitin Lingayat & Geeta Karambelkar · Journal of Pharmaceutical Research International · 2021

Mortality rate caused by dengue in tropical urban life by a vector mosquito possess severe effects including children. This is an observational study carried out in a tertiary care hospital in Navi Mumbai, from June 2006 to August 2008 area which is endemic for vector borne disea...

Open access Research Article 10.9734/jpri/2021/v33i43A32465

Effect of Relationship between Protein Oxidation and Total Thiols in Progression of Leprosy

A. D. Kadam, D. M. Khopade, A. V. Sontakke & S. A. Abhang · Journal of Pharmaceutical Research International · 2021

Objective: In several countries including India, leprosy is an older disease & until now continuous to be an important health issue. Leprosy is a chronic granulomatous disease, the causative agent for which is mycobacterium leprae. Due to imbalance between natural antioxidant...

Open access Research Article 10.9734/jpri/2021/v33i43A32467

Case Report on Post Operative Case of Exploratory Laparotomy for Ruptured Ectopic Pregnancy with Septicemia

Arati Raut, Ruchira Ankar, Samruddhi Gujar, Savita Pohekar & Sheetal Sakharkar · Journal of Pharmaceutical Research International · 2021

Introduction: Extra uterine pregnancy is a first-trimester pregnancy problem that affects 1.3–2.4 percent of all pregnancies. The key signs of the ectopic pregnancy are abdominal discomfort and vaginal bleeding along with Sharp, dull, or cramping pains may be experienced around 5...

Open access Research Article 10.9734/jpri/2021/v33i42B32453

Role of Curcuma Longa in Type 2 Diabetes and its Associated Complications

Waseem Abbas, Rafeeq Alam Khan, Mirza Tasawer Baig, Safdar Ali Shaikh & Andeep Kumar · Journal of Pharmaceutical Research International · 2021

Background: Occurrence of Diabetes and its related complications increased all over the world due to recent lifestyle trends.  A higher proportion of ultra-processed foods in the diet have been associated with a higher risk of T2D. A lack of fiber and a surplus of refined simple...

Open access Research Article 10.9734/jpri/2021/v33i42B32454

An Overview on the Epidemiology, Pathophysiology and Treatment of Vitiligo: A Review

Dhaifallah Alrokwi Alenizi, Abdulrahman Munis W. Al-Ruwaili, Wael Salamah Thiyab Alanazi, Abdulazez Aweed Mehdy Alonezy, Talal Ahmed A. Albalawi, Rahaf Meshal L. Alanazi, Sama Abdulfattah M. Al Madani & Luluah Maan Ramadan Abdullah · Journal of Pharmaceutical Research International · 2021

Vitiligo is one of the complex diseases that has existed during the entire history of humanity and so far we have not fully understood it, serval theories have been proposed most of them suggest strong linkage between deficiencies in certain genes and the disease, refereeing that...

Open access Research Article 10.9734/jpri/2021/v33i42B32456

The Effects of Lubricants on the Disintegration and Dissolution Profile of Metronidazole Tablets Formulated Using Sida acuta Gum as a Binder

Sinodukoo Eziuzo Okafo, Avbunudiogba John Afokoghene, Christian Areruruoghene Alalor & Deborah Ufuoma Igbinake · Journal of Pharmaceutical Research International · 2021

Aims: This research was done to study the effects of types and concentrations of lubricants on the dissolution and disintegration profile of metronidazole tablets formulated using Sida acuta gum as a binder. Methodology: Sida acuta gum (SAG) was extracted from powdered dried leav...

Open access Research Article 10.9734/jpri/2021/v33i42B32452

Comparing the Efficacy of 2% Diltiazem Gel with 0.2% Glyceryl Trinitrate in Anal Fissure

Ehsanullah Malik, Sania Bhatti, Qararo Shah, Muharram Ali Abbasi, Khushbakhat Abro, Vaqar-E-Sahar Shah, Fahad Jibran Siyal, Dua Rabel Siyal, Sumbul Masood, Abdul Basit Gopang & Arsalan Humayun · Journal of Pharmaceutical Research International · 2021

Objective: To compare the efficacy of 2% diltiazem gel with 0.2% glyceryl trinitrate in patients presenting with chronic anal fissure at Tertiary Care Hospital, Larkana. Methodology: This prospective comparative Study was conducted at department of Surgery ward-II Chandka Medical...

Open access Research Article 10.9734/jpri/2021/v33i42B32457

Compression of Hamstring and Quadriceps Muscles Strength in Patients with Osteoarthritis of Knee and Normal individual

M. Shukla & L. Parmar · Journal of Pharmaceutical Research International · 2021

Objectives: 1. To assess the strength of hamstring and quadriceps in patients with knee OA with 1 RM. • To compare the strength of hamstring and quadriceps with normal individuals. Research Design: Observational study. Introduction: Quadriceps and hamstring muscle weakness is com...

Open access Research Article 10.9734/jpri/2021/v33i43A32458

To Assess the Efficacy of Lactational Counseling for Prevention of Breast Engorgement

Pradnya Gavhale & Shalini Moon · Journal of Pharmaceutical Research International · 2021

Background: Breast engorgement is a swollen, painful breast and overfilling with breast milk. In lactating mothers this condition is common during the puerperal period. Breast engorgement developed inside the breast due to expansion and pressure exerted by the synthesis and stora...

Open access Research Article 10.9734/jpri/2021/v33i43A32459