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All published articles 7450

Case Report on Cerebral Palsy- with Ayurvedic Treatment Protocol

Sudhir Kumar Pani, B. B. Khuntia & Sudarshan Behera · Journal of Pharmaceutical Research International · 2021

Cerebral palsy is a non-progressive disorder, which arising in early stages of development of child. There are many etiology factors like antenatal, natal and postnatal factors responsible for causing cerebral palsy but exact cause is still unknown. Spasticity is the main feature...

Open access Research Article 10.9734/jpri/2021/v33i43A32463

Pharmacy Impact for Distinguishing Normal Face from Abnormal Face Due to COVID- 19

Payal Bose, Shawni Dutta, Vishal Goyal & Samir K. Bandyopadhyay · Journal of Pharmaceutical Research International · 2021

In today’s world face detection is the most important task. Due to the chromosomes disorder sometimes a human face suffers from different abnormalities. In the recent scenario, the entire globe is facing enormous health risks occurred due to Covid-19. To fight against this deadly...

Open access Research Article 10.9734/jpri/2021/v33i43A32460

Development and Evaluation of Floating Microspheres of Sumatriptan Succinate using Ethyl Cellulose and Mucilage Extracted from Vigna Mungo

Nilesh S. Kulkarni, Mukta A. Kulkarni, Rahul H. Khiste, Mohini C. Upadhye & Shashikant N. Dhole · Journal of Pharmaceutical Research International · 2021

Aim: The present investigation is to formulate and evaluate gastroretentive floating microspheres for sumatriptan succinate. Gastric retention is widely used approach to retain dosage form in stomach and to enhance absorption of drugs. Methods: The gastroretentive floating micros...

Open access Research Article 10.9734/jpri/2021/v33i43A32461

Development, Validation and Forced Degradation Study of Emtricitabine and Tenofovir Alafenamide in its Pharmaceutical Dosage Form Using RP-HPLC

Khushboo Patel, Ujashkumar Shah, Hirak Joshi, Jayvadan K. Patel & Tejas B. Patel · Journal of Pharmaceutical Research International · 2021

Aims: The present research was aimed to develop and validate a reverse phase high performance liquid chromatographic (RP-HPLC) method for the quantification of Emtricitabine (EMT) and Tenofovir Alafenamide (TEN) in combination. Methodology: Separation was achieved under optimized...

Open access Research Article 10.9734/jpri/2021/v33i43A32462

Determining the Effectiveness of Different Reconstruction Method and Mandibular Implants for Fracture in the Mandible

Maryam Hassannia & Sajad Ghorbanizadeh · Journal of Pharmaceutical Research International · 2021

Introduction: Every year, many people suffer from mandibular defects due to various reasons such as trauma or malignant tumors. Various techniques for reconstructing mandibular defects have always been considered by surgeons and maxillofacial specialists to select the best option...

Open access Research Article 10.9734/jpri/2021/v33i42B32443

Role of Pharmacists in Health Care: A Review on Pharmacist and Consumer Views

Haritha Mohanan, Aiswarya Rajesh, V. V. Aswathi & A. Sareena · Journal of Pharmaceutical Research International · 2021

As a member of the therapeutic team, pharmacists should be directly involved in patient healthcare. Many studies over the last few years have shown that pharmacists providing pharmaceutical care services can enhance patients’ clinical status and health care outcomes. However, dif...

Open access Research Article 10.9734/jpri/2021/v33i42B32444

A Review on Antimicrobial Stewardship Programs in Multiple Care Settings

Aiswarya Rajesh, Haritha Mohanan & Rajeev P. Thomas · Journal of Pharmaceutical Research International · 2021

Antimicrobial resistance is a global problem that is regarded as one of the most important threats to human health. Misuse of antibiotics leads to an increase in antibiotic resistance as well as higher healthcare costs. Antimicrobial stewardship is a coordinated, multidisciplinar...

Open access Research Article 10.9734/jpri/2021/v33i42B32445

Selective Optimization of Side Activities (SOSA) as an Efficient Approach for Generation of New Leads from Old Drugs

Preeti P. Mehta, Yogita Ozarde, Ranjit Gadhave & Arti Swami · Journal of Pharmaceutical Research International · 2021

The selective optimization of side activities (SOSA) approach appears to be a promising strategy for lead generation. In this approach old drugs are used to generate new hits or leads. The objective of SOSA is to prepare analogues of the hit molecule in order to transform the obs...

Open access Research Article 10.9734/jpri/2021/v33i42B32447

The Role of Mitochondrial Energetics and Inflammasome NLRP3 in Diabetic Cardiomyopathy

Maha Almas, Usaal Tahir, Mariam Zameer, Maham Mazhar, Qurban Ali, Ayesha Rafique & Khushbukhat Khan · Journal of Pharmaceutical Research International · 2021

Diabetic Cardiomyopathy is the worldwide leading cause of lethal heart disorders burdening the healthcare systems. Mitochondrion is the key regulator of myocardial metabolism. It fuels the cardiocytes and regulates the pumping activity of heart. People living with diabetes have d...

Open access Research Article 10.9734/jpri/2021/v33i42B32449

Review on Abhrasindoora: A Sublimated Mercurial Formulation as a Herbo-Bio-Mineral Metallic Compound for Respiratory Ailments

Rakesh Bramhankar, Jaimini Arya, Abhaya Kumar Mishra, Snigdha Das, Nisha Munishwar & H. Raghuveer · Journal of Pharmaceutical Research International · 2021

Abhrasindoora is a unique mercurial formulation as a herbo-bio-mineral metallic compound which is mentioned under Kupipakwa Rasayana Prakarana in Rasendra Sambhava. There are four formulations are mentioned with the name of Abhrasindoora, amongst them one in Rasendra Shambhava an...

Open access Research Article 10.9734/jpri/2021/v33i42B32451

Age-Related Haematological Variations in Patients with Asymptomatic Malaria in Akure, Ondo State, Nigeria

Emmanuel Ifeanyi Obeagu, Ayomiposi Ibironke Busari, Immaculata Ogochukwu Uduchi, I. A. Ogomaka, Adaobi Maryann Ibekwe, C. C. N. Vincent, Udunma Olive Chijioke, Chukwuma J. Okafor, Henshaw U. Okoroiwu & Calista Ndidi Adike · Journal of Pharmaceutical Research International · 2021

Background: Malaria is a life-threatening infectious disease of widespread burden. Malaria remains a leading communicable disease in the developing countries of the world. It occurs mostly in the tropical and subtropical regions and accounts for considerable morbidity and death....

Open access Research Article 10.9734/jpri/2021/v33i42B32441

Evaluation of the Cold Chain Expanded Program on Immunization at Governmental and Private Health Care Centers in Riyadh City, Saudi Arabia

Abdulrahman Hussain Alqahtani, Suhair Alsaleh & Abdulaziz Almana · Journal of Pharmaceutical Research International · 2021

Objective: Vaccine storage is essential to ensure optimal vaccine effectiveness. Cold chain is a series of storage and transport links, designed to keep the vaccine at the correct temperature till it reaches the user. To evaluate the Cold Chain Expanded Program on Immunization at...

Open access Research Article 10.9734/jpri/2021/v33i42B32442

An Eco-friendly RP-HPLC and UV-Method Development and Validation for an Estimation of Tolvaptan in Bulk and Tablet Dosage form Followed by Forced Degradation Studies

Patel Seema A., Sayyed Nazifa S., Lajporiya Mobina I., Manjra Mehfuza U., Aejaz Ahmed & G. J. Khan · Journal of Pharmaceutical Research International · 2021

Aims: To develop and validate a new, simple, rapid, precise, and accurate An Eco-friendly RP-HPLC and UV-Method Development and Validation for an estimation of Tolvaptan in Bulk and Tablet dosage form followed by Forced Degradation Studies Place and Duration of the Study: The pre...

Open access Research Article 10.9734/jpri/2021/v33i42B32446

Effect of Daclatasvir and Sofosbuvir Therapy on Serum Levels of Angiogenic Factors: A Prospective Cohort Study

Eman M. Hamdy, Nashwa A. Shebl & Tarek M. Mostafa · Journal of Pharmaceutical Research International · 2021

Background: Direct-acting antiviral agents therapy is considered a breakthrough in hepatology due to high rates of sustained virologic response in all patients including those with decompensated cirrhosis. However, impact of Direct-acting antiviral agents-induced sustained virolo...

Open access Research Article 10.9734/jpri/2021/v33i42B32448

Anti-Atherosclerosis and Anti-Hypertensive Effects of Flavonoid Isorhamnetin Isolated from the Bark of Cordia dichotoma L

Syed Salman Ali, Mohammad Asif & Najam Ali Khan · Journal of Pharmaceutical Research International · 2021

Aims: This study aimed to investigate the anti-atherosclerotic and anti-hypertensive ability of isolated Isorhamnetin from the bark of Cordia dichotoma L. Study design: Experimental study Place and Duration of Study: The extraction and isolation of bark of Cordia dichotoma L bark...

Open access Research Article 10.9734/jpri/2021/v33i42B32450