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All published articles 7450

Study of the effect of Baricitinib on the Course of COVID-19

Alina Yuryevna Maslova, Alla Aslanbekovna Tskaeva, Zuleykha Abdulkerimkizi Ashurova, AlinaTemrukovna Abazova, Magomed Muradovich Ismailov, Maryam Muradovna Ismailova, Igor Spartakovich Baklanov, Artem Evgenevich Mishvelov, Sergey Nikolaevich Povetkin & Olga Aleksandrovna Baklanova · Journal of Pharmaceutical Research International · 2021

The aim of the study was to determine the effect of the inhibitor of janus kinase – baricitinib ("Olumiant") on the course of COVID-19. This drug baricitinib is able to suppress the systemic inflammatory response, which is one of the common causes of death in COVID-19, is an urge...

Open access Research Article 10.9734/jpri/2021/v33i35A31890

Assessment of Risk Factors Associated with Low-Birth-Weight Neonates in a Tertiary Care Teaching Hospital: A Case-Control Study

Rajesh Hadia, Riya Gandhi, Padmja Dave, Niyati Patel, Dhaval Joshi, Trupal Rathod, Manish Rasania & Hemraj Singh Rajput · Journal of Pharmaceutical Research International · 2021

Background: Low birth weight (LBW) is still a significant public health problem globally and is associated with a range of both short- and long-term consequences. Overall, it is estimated that 15% to 20% of all births worldwide are low birth weight, representing more than 20 mill...

Open access Research Article 10.9734/jpri/2021/v33i35A31891

Causes and Management of Hyperkyphosis

Khaled Nasser Almujel, Abdalah Emad Almhmd, Abdulrahman Arshed N. Alharfy, Ibrahim Abdullah Said Albalawi, Tariq Bander F. Alanazi, Aysha Jaber Alshehri, Bedour Eid H. Alatawi, Abdullah Dhafer Alshehri, Meshari Salman Alhawiti & Shumoukh Homoud Alshehri · Journal of Pharmaceutical Research International · 2021

Hyperkyphosis is identified when kyphosis angle exceeds the normal ranges. In overall, hyperkyphosis upsurges with age, particularly after the age of 40. It arises as a consequence of multifactorial causes and is associated with increased health susceptibility. Separately from th...

Open access Research Article 10.9734/jpri/2021/v33i35B31892

An Observational Study on Drug Utilization Pattern in Chronic Kidney Disease Patients using Anti-Hypertensive Drugs in a Tertiary Care Teaching Hospital

Rajesh Hadia, Hemraj Singh Rajput, Vidhi Mehta, Pushti Shah, Arti Muley, Jyoti Thakkar, Trupal Rathod, Dhaval Joshi, Rajesh Maheshwari & Vikas Chandrakar · Journal of Pharmaceutical Research International · 2021

Background: There is a strong relationship between Hypertension and chronic kidney disease. HTN is highly prevalent in CKD patients, contributing to high cardiovascular risk. Objectives: This study aims drug utilization pattern of Antihypertensive drugs in CKD. The objective of t...

Open access Research Article 10.9734/jpri/2021/v33i35B31893

Effectiveness of Healthcare and Fitness Influencers during COVID Times

Tushar Kumar Roy & Smita Mehendale · Journal of Pharmaceutical Research International · 2021

Influencer marketing has played a significant role in marketing to present its products on a digital platform. In this study, we are trying to gauge the effectiveness of healthcare and fitness influencers on Instagram. More specifically, the researchers are trying to find how the...

Open access Research Article 10.9734/jpri/2021/v33i35B31894

Natural Products in Drug Discovery: Approaches and Development

Pious Soris Tresina, Murugeswaran Santhiya Selvam, Authinarayanan Rajesh, Asirvatham Doss & Veerabahu Ramasamy Mohan · Journal of Pharmaceutical Research International · 2021

Historically, natural products (NP’s) have played a significant role in drug discovery, not only in cancer and infectious diseases, but also in other therapeutic  areas including cardiovascular diseases and multiple sclerosis. Profit and loss, Partnerships and averages, natural p...

Open access Research Article 10.9734/jpri/2021/v33i35A31879

A Prospective Study on Adverse Drug Reactions in Inpatients of General Medicine Department in a Tertiary Care Hospital- A clinical Pharmacist-led Study

Shereen Hassan, U. Ujwal Kumar, Venessa Mascarenhas, G. Suresh, K. C. Bharath Raj & Prashant Nayak · Journal of Pharmaceutical Research International · 2021

The present study was carried out to determine the incidence of Adverse Drug Reactions (ADRs) in general medicine department and to assess and analyze the causality, severity, and preventability of ADRs. A prospective observational study was conducted in the general medicine depa...

Open access Research Article 10.9734/jpri/2021/v33i35A31880

Synthesis, Characterization and Biological Evaluation of Thiazolidinedione Derivative as Novel Antidiabetic Agents

Shivkant Patel, Ashim Kumar Sen, Dillip Kumar Dash, Piyushkumar Sadhu, Mamta Kumari & Sunil Bhaurao Baile · Journal of Pharmaceutical Research International · 2021

Thiazolidinedione derivative have Antihyperglycemic activity, they are agonists for the peroxisome proliferator-activated receptor (PPAR), which controls glucose synthesis, transport, and utilization via regulating the transcription of insulin-responsive genes. A number of novel...

Open access Research Article 10.9734/jpri/2021/v33i35A31881

Synthesis, Insilico and Antibacterial Activity Studies of Substituted Dihydro-1, 2-Oxazole Benzopyran-2-One Hybrids

Alphonsus D’souza, Pankaj Kumar, Abhishek Kumar, Soundarya M. Rai & Prashant Nayak · Journal of Pharmaceutical Research International · 2021

A series of substituted dihydro-1, 2-oxazole benzopyran-2-one (SR1-SR6) were synthesized through the intermediate substituted benzopyran-2-one chalcones and were characterized using spectral analysis.   Compounds were docked with receptor DNA Gyrase B (PDB code: 5L3J) to know its...

Open access Research Article 10.9734/jpri/2021/v33i35A31882

Knowledge Attitude and Practices in Community Health Programs by the Pharmacists in Lahore, Pakistan

Rehan Ahmad Khan Sherwani, Maria Aslam, Sajjad Ali Gill, Muhammad Farooq, Sana Saeed, Amna Younas & Hira Shahid · Journal of Pharmaceutical Research International · 2021

Introduction: A public health program intends to improve the health care services in society to lessen the disease burden particularly in the case of non-infectious diseases. This research work investigates the knowledge, practice, and attitude of pharmacists in community health...

Open access Research Article 10.9734/jpri/2021/v33i35A31883

A Study on Adverse Transfusion Reactions in a Secondary Care Hospital of Rural India

Bogireddy Sahithi, Polamada Prathyusha, Kandibedala Chandana Sree, Ramagoni Alekya, Goruntla Narayana & N. Hariharanadha Sarma · Journal of Pharmaceutical Research International · 2021

Aims: The study aims to assess the incidence, causality, and severity of adverse transfusion reactions in patients transfused with blood or blood components at a secondary care referral hospital. Study Design: A prospective observational study was conducted in the secondary care...

Open access Research Article 10.9734/jpri/2021/v33i35A31884

Prevalence of Sports Injuries before and during COVID-19 Quarantine among Adults of Riyadh, Saudi Arabia

Moaath A. Alamir, Reem A. AlMohaini, Ahmed A . Alharbi, Mohammad K. Almazied, Ghada F. AlSwaji & Yousef T. Khoja · Journal of Pharmaceutical Research International · 2021

Aims: This study aims to compare the incident rate of sports injuries before and during the COVID-19 quarantine among active and nonactive adults and identify and compare patterns, types and sites of sports injuries. Study Design: Cross-sectional study. Place and Duration of Stud...

Open access Research Article 10.9734/jpri/2021/v33i35A31886

Detecting the Cause of Depression using BECK Depression Scale among Patients

Jaya Gawai, Pooja Kasturkar & Trupti Uke · Journal of Pharmaceutical Research International · 2021

Background: The onset of Depression is a cause of concern. And various factors have been found to spark off this psychological set back among different groups of people.   Aim: This investigation aims to identify various trigger factors causing depression. BECK Depression scale w...

Open access Research Article 10.9734/jpri/2021/v33i35A31887

Formulation, Overall Acceptability, Nutritive Value Assessment of Gluten-free, Vegan Bread and Comparison with Contemporary Gluten-free Bread

Akansha Laddha, Pankaj Deshpande, Shamal More & Radhika Hedaoo · Journal of Pharmaceutical Research International · 2021

Gluten-free and vegan bakery items have been gaining popularity. Their demand has increased over the past few years, with India being one of the largest gluten-free food consumers. The gluten-free pieces of bread available in the market are crumbly in nature and have a dry mouthf...

Open access Research Article 10.9734/jpri/2021/v33i35A31888