Background: All drug regulatory authorities have to ensure the safety, efficacy and quality of all the marketed products. Quality and efficacy can be determined by the data from preclinical and clinical trials. In clinical trials at the pre-marketing stage, it is challenging to i...
Open access
Research Article10.9734/jpri/2021/v33i32A31720
Aim: To identify the potential renal protective effect produced by astaxanthin on streptozotocin-produced diabetic kidney disease in rats. Study Design: Male Wistar rats (n=60) were separated into six groups, control, diabetic (streptozotocin 45 mg/kg single intraperitoneal injec...
Open access
Research Article10.9734/jpri/2021/v33i32A31721
BACKGROUND: Flexibility is important for general health and fitness, athletic performance, injury prevention and rehabilitation. Sedentary behavior of students leads to decreased physical fitness levels which affects flexibility. There is little evidence regarding relationship be...
Open access
Research Article10.9734/jpri/2021/v33i32A31723
Objective: To determine the outcome of surgical removal of oral pyogenic granuloma in terms of post-operative pain (POP), post-operative healing and post-operative infection. Materials and methods: This observational study was conducted at Oral and Maxillofacial Surgery departmen...
Open access
Research Article10.9734/jpri/2021/v33i32A31724
Introduction: Ginger and honey have shown to be effective against pathogens routinely encountered in periodontal infection. However, none of literature has shown antibacterial effect of ginger and honey on the levels of dental plaque when used as a gel. Aim: To compare the effec...
Open access
Research Article10.9734/jpri/2021/v33i32A31725
Aims: To evaluate pharmacoeconomics for the vaccination of COVID-19 vaccine and analyze the cost-effectiveness for the vaccine in Ukraine. Study design: we have analyzed using models for the economics of coronavirus vaccine. Place and duration of study: Sample: population of Ukr...
Open access
Research Article10.9734/jpri/2021/v33i32A31727
Aims: to explore the prevalence of knee symptoms in the general population of Riyadh, Saudi Arabia, and evaluate the impact of sports participation and other demographic variables on the progression of knee symptoms in Riyadh, Saudi Arabia. Study design: Cross-sectional study Pl...
Open access
Research Article10.9734/jpri/2021/v33i32A31729
Dental caries and Periodontitis are the most commonly reported dental diseases. These can lead to loss of tooth structure and compromising the functions of teeth like mastication and thus affecting the overall health. Periodontitis is inflammation of periodontium resulting in los...
Open access
Research Article10.9734/jpri/2021/v33i32A31716
Background: Part of becoming a good nurse is being able to understand one’s own perception of death and dying, which can affect the quality of care a patient with terminal illness will receive. This study was carried out to assess the nurses perception towards the care of patient...
Open access
Research Article10.9734/jpri/2021/v33i32A31714
The antiemetic effect of aqueous and methanolic extracts of R. graveolens in young chicks was investigated. In addition, the phytochemical screening of the test plant and its acute toxicity studies were also conducted. Different doses of the extracts were tested for their antieme...
Open access
Research Article10.9734/jpri/2021/v33i32A31715
Misbahuddin M. Rafeeq, Ziaullah M. Sain, Norah A. Alturki, Ahmad Alzamami, Saeed A. Asiri, Mutaib M. Mashraqi, Amany I. Alqosaibi, Mashael M. Alnamshan, Abdulrahman Almutairi, Abdulkhaliq Munawir Alanazi & Qamre Alam·Journal of Pharmaceutical Research International·2021
Aromatase plays a significant role in the progression of estrogen receptor-positive (ER-positive) breast cancer. The adverse side effects of currently used aromatase inhibitors (AIs) necessitate the development of new AIs that are more active, selective, and less toxic. This stud...
Open access
Research Article10.9734/jpri/2021/v33i32A31717
Angiotensin is a hormone that plays a key role in the development of hypertension. Angiotensin-Converting Enzyme (ACE) inhibitors and Angiotensin Receptor Blockers (ARBs) are now the most often prescribed drugs to treat hypertension. The present in silico study involves exploring...
Open access
Research Article10.9734/jpri/2021/v33i32A31718
Objective: Current scientific investigations have evidenced that there is increased attention in developing novel drugs from bio source for the human health concern. This study's main objective was to intervene phytochemical constituents present in the ethanol leaf extract of an...
Open access
Research Article10.9734/jpri/2021/v33i32A31711
Dyslipidaemia an ever increasing menace emerging out of present lifestyle, is one of the major risk factors for developing Cardio-vascular abnormalities like Coronary Artery Disease (CAD), Myocardial infarction (MI), Cardiac arrest and is often associated with other metabolic dis...
Open access
Research Article10.9734/jpri/2021/v33i32A31713
Aims: Rheumatoid arthritis (RA) is characterized by the onset of oxidative stress. This study aimed to evaluate the enhancing of extra virgin olive (EVOO) and Evening primrose oil (EPO) on oxidative stress and liver enzymes in male Wistar rats and compare between them. Place and...
Open access
Research Article10.9734/jpri/2021/v33i32A31712