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All published articles 7450

Enhancement of Solubility and Dissolution Rate of BCS Class-II Fluvoxamine Tablets using Solvent Evaporation Solid Dispersion Technique

Martha Srinivas & Anoop Singh · Journal of Pharmaceutical Research International · 2021

Aim: This research work was aimed to formulate Enhancing the solubility of Poorly soluble drug i.e. Fluvoxamine tablets by the solvent evaporation method, Fluvoxamine medicament is a selective serotonin reuptake inhibitor (SSRI) antidepressant agent. Purpose: The BCS class II dru...

Open access Research Article 10.9734/jpri/2021/v33i31B31689

Comparative Pharmaceutical Standardization and Oral Bioavailability Study on Praval Pishti and Praval Bhasma

Megha Satpute, Bharat Rathi, Anita Wanjari & Mujahid Khan · Journal of Pharmaceutical Research International · 2021

Background: Praval (coral) is a very usually occurring calcium form. It is rich source of calcium & minerals. As per text it can be converted into two formulas which are bhasma (calcinated ash) and pishti(powdered form without agni).These forms may have different rate of imme...

Open access Research Article 10.9734/jpri/2021/v33i31B31690

Atlanta Classification for Acute Pancreatitis- A Study Protocol

Varun Singh, Rajasbala Pradeep Dhande & Gaurav Mishra · Journal of Pharmaceutical Research International · 2021

Background: Acute pancreatitis is one of the most common abdominal pathologies having variable outcome ranging from self limiting abdominal pain to high mortality and morbidity due to organ failure, over the past five decades, various classification systems have emerged to classi...

Open access Research Article 10.9734/jpri/2021/v33i31B31691

Correlation of Glycosylated Hemoglobin and Complexity of Coronary Artery Disease among Aged ≥45 Years Population with Diabetes Mellitus

Faraz Farooq Memon, Muhammad Kashif, Zain Islam Arain, Syed Ahsan Raza, Mehboob Ali, Muhammad Tahseen Raza & Feroz Memon · Journal of Pharmaceutical Research International · 2021

Objective: Cardiovascular diseases are 1.7 times more prevalent in patients with diabetes mellitus. The aim behind this study was to examine the correlation of glycosylated hemoglobin and complexity of coronary artery disease among middle aged population with diabetes mellitus Pa...

Open access Research Article 10.9734/jpri/2021/v33i31B31693

Pharmaceutical Development, Standardization and Clinical Evaluation of Efficacy of a Polyherbal Hair-Pack and Hair Gel in Dandruff Control

Poonam Madan, Bharat Rathi, Renu Rathi, Sonali Wairagade & Dhiraj Zade · Journal of Pharmaceutical Research International · 2021

Introduction: Dandruff is a commonly found hair problem affecting all age groups with high recurrence and is considered a social stigma. In Ayurved it is compared with Darunak falling under the category of kshudrarogadhikar and is caused due to the vitiation of vaat and kapha. Tr...

Open access Research Article 10.9734/jpri/2021/v33i31B31692

Quality of Life after Ablation vs Medication Therapy in Patients With Supraventricular Tachycardia

Abdul Mueed, Nandlal Rathi, . Shahzad, Jibran Ashraf, Salman Ahmed & Lajpat Rai · Journal of Pharmaceutical Research International · 2021

Objective: Supraventricular tachycardia (SVT) is the most common presentation of patients at cardiac emergency department. This study aims to determine the quality of life in patients with supraventricular tachycardia after they treated with medicines vs. ablation therapy. Method...

Open access Research Article 10.9734/jpri/2021/v33i31B31694

A Comparative Evaluation of Efficacy of Mustadi Yapan Bastiand Baladi Yapan Basti in the Management of Oligozoospermia-Study Protocol

Abhijit Murlidharrao Ahire, Shweta Parwe & Milind Nisargandha · Journal of Pharmaceutical Research International · 2021

Background: Nowadays most upcoming disease that affecting 8 to 12% of the world population is Infertility.The affected area of this problem have no bar irrespective of metro cities as well as small towns population..Modern treatment with steroids and other medication and interven...

Open access Research Article 10.9734/jpri/2021/v33i31A31686

Evaluation of Performance of IHI Global Trigger Tool in Identification of Adverse Drug Events: A Prospective Observational Study

Narayana Goruntla, Krishna Yasaswini Nitturi, Krishnapriya Pujari, Lavanya Jayanthi, Venkata Ramana Gurram, Kasturi Vishwanathasetty Veerabhadrappa & Pradeepkumar Bhupalam · Journal of Pharmaceutical Research International · 2021

Aims: The study aims to evaluate the performance of the Institute for Healthcare Improvement (IHI) global trigger tool in the identification of adverse drug events. Study design: Prospective observational study. Place and duration of study: The study was conducted in a General Me...

Open access Research Article 10.9734/jpri/2021/v33i31A31675

Clinical Characteristics of Urogenital Fistulas in PMCH Nawabshah: A Cross-sectional Study

Aneela Tehzeen, Hazooran Lakhan, Shazia Awan, Mona Rani, Shahida Baloch, Muhammad Ali Suhail & Arslan Ahmer · Journal of Pharmaceutical Research International · 2021

Objective: To analyze the clinical characteristics of urogenital fistulas reported at PMCH Nawabshah.  Methodology: A cross-sectional study, concluded in three years from January 2018 to December, 2020 in all ages patients with urogenital fistulas (UGF). The referred cases of UGF...

Open access Research Article 10.9734/jpri/2021/v33i31A31676

A Validated Reversed-Phase HPLC Analytical Method for the Analysis of Rosuvastatin Calcium in Bulk Drug and Tablet Dosage Formulation

Awdhut D. Pimpale & Rajendra Kakde · Journal of Pharmaceutical Research International · 2021

Aims: The current research work has desired the validated reversed-phase analytical technique for the assurance of rosuvastatin calcium in bulk and tablet formulation. Study design: Experimental research work. Place and duration of study: UDPS, RTM Nagpur University, Nagpur, Maha...

Open access Research Article 10.9734/jpri/2021/v33i31A31677

Development and Characterization of Pioglitazone Nanoparticles for the Effective Treatment of Diabetes Mellitus

Revathi A. Gupta & P. Odaya Kumar · Journal of Pharmaceutical Research International · 2021

Pioglitazone is designated as a BCS class II medication since it is weakly water soluble.The goal of this study was to create starch nanoparticles for the administration of Pioglitazone in attempt to lessen dose-related side effects and maybe prolong its release in the treatment...

Open access Research Article 10.9734/jpri/2021/v33i31A31678

Role of Green Tea on Obesity and Type-II Diabetes Mellitus Male Individuals

Tazeen Shah, Saira Dars, Saima Ashfaque Sheikh, Farheen Shaikh, Shafaq Ansari, Naheed Akhtar & Arslan Ahmer · Journal of Pharmaceutical Research International · 2021

Objective: To evaluate the effects of Green tea on obesity and hyperglycemia. Methodology: This observational study was carried out at the department of physiology, in affiliation to Medical Research Centre Liaquat University of Medical and Health Sciences Jamshoro. The sample wa...

Open access Research Article 10.9734/jpri/2021/v33i31A31679

Antifungal Effect of Different Plant Extracts against Phytopathogenic Fungi Alternaria alternata and Fusarium oxysporum Isolated from Tomato Plant

Haytham M. Daradka, Abdelrahman Saleem & Wael Abdulghani Obaid · Journal of Pharmaceutical Research International · 2021

The antifungal activity of 10 plant extracts was tested against the phytopathogenic fungi, Alternaria alternata and Fusarium oxysporum, the pathogens of early blight and wilt diseases of tomato. Plants tested related to different families. Three doses (10, 50 and 100 mg/ml) of pl...

Open access Research Article 10.9734/jpri/2021/v33i31A31681

In vivo and In vitro Antifungal Activity of 2,3-Dimethylquinoxline

Abdelbagi Alfadil, Hamoud A. Alsamhan, Ahmed S. Ali, Huda M. Alkreathy, Mohammad W. Alrabia & Hani Y. Abdullah · Journal of Pharmaceutical Research International · 2021

Aims: To explore the antifungal activity of 2,3-dimethylquinoxaline. Study Design: A preclinical study of a compound against 10 fungal species. Backgrounds: Severe fungal infections cause significant clinical problem and need more effort to search for new antifungals. Methodology...

Open access Research Article 10.9734/jpri/2021/v33i31A31684

Phytopharmacological Assessment of Some Medicinal Plants of Thal Desert of Pakistan

Zunaira Khalid, Ghulam Yasin, Adeela Altaf, Syeda Amna Batool, Asma Kanwal & Sobia Sohail · Journal of Pharmaceutical Research International · 2021

The presence of secondary metabolites and various ions in a plant determines its phytophamacological potential. Desert plants are adapted to stressful environmet by synthesizing secondary metabolites and ions accumulation as osmoticum.The present study was conducted to evaluate t...

Open access Research Article 10.9734/jpri/2021/v33i31A31687