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All published articles 7450

Changes in the Levels of Biochemical Markers Following Coronavirus Infection in Patients with Liver Disease, Renal Disease and Diabetes Mellitus as Compared to Control Participants: A Cross Sectional Study

Osama J. Ahmed, Estabraq A. Al-Wasiti, Dina Jamil & Hayder A. Al-Aubaidy · Journal of Pharmaceutical Research International · 2021

Background & Aim of the Study: Increased levels of many biomarkers, including liver enzymes, blood urea and serum creatinine as well as glycemic markers have been reported following coronavirus (COVID-19) infection, leading to the development of acute disease. This study aims...

Open access Research Article 10.9734/jpri/2021/v33i30B31648

Development and Validation of New RP-HPLC Method for the Estimation of Antidiabetic Drugs Metformin Hydrochloride and Gemigliptin in Combined Pharmaceutical Dosage Form

Suleman S. Khoja & Laxman J. Patel · Journal of Pharmaceutical Research International · 2021

Metformin Hydrochloride and Gemigliptin is combination of Antidiabetic drug in tablet Zemimet SR ® Tablet (25/500 mg), a member Antidiabetic drug, is a recent drug developed by LG Life sciences for the treatment of Type 2 diabetes. A new sensitive and rapid HPLC method was develo...

Open access Research Article 10.9734/jpri/2021/v33i30B31649

Outcome of Intramedullary Interlocking Nailing in the Management of Gustillo-I Diaphyseal Fracture of Tibia

Santosh Kumar, Faheem Ahmed Memon, Siraj Ahmed Butt, Shakeel Ahmed Memon, Iftikhar Ahmed Memon & Aamir Usman Memon · Journal of Pharmaceutical Research International · 2021

Objective: To evaluate the outcome of intramedullary interlocking nailing in the management of Gustillo-I diaphyseal fracture of tibia. Study Design: This is an observational study. Setting: Study carried out at Orthopaedic Surgery department, Liaquat University of Medical and He...

Open access Research Article 10.9734/jpri/2021/v33i30B31650

Effects of Health Education Program and Improving Self-care among Vietnamese Adult Patients with Chronic Heart Failure in Nam Dinh Province Vietnam

Ngo Huy Hoang & Pham Thi Hong Nhung · Journal of Pharmaceutical Research International · 2021

This study aimed toimprove the knowledge and practice of self-care among Vietnamese adult patients with chronic heart failure in Nam Dinh province Vietnam. The one group pre-test and post-test educational intervention was conducted among 90patients with chronic heart failurein Na...

Open access Research Article 10.9734/jpri/2021/v33i30B31651

Characteristics of Masked Hypertension in Diabetes Mellitus Patientstype 2

Vu Thanh Binh, Nguyen Le Thuy & Le Minh Hieu · Journal of Pharmaceutical Research International · 2021

Monitoring blood pressure with a continuous blood pressure monitor to carry around to detect masked hypertension (MH) in type 2 diabetes patients who are on outpatient treatment at Thai Binh Medical University Hospital, Thai Binh, Vietnam. Objective: Analysis of MH characteristic...

Open access Research Article 10.9734/jpri/2021/v33i30B31652

Study of Nidan (Etiological Factors) Responsible For Manyastambha With Respect To Cervical Spondylosis in Present Era – A Study Protocol

Mayuri Jain, Shweta Parwe, Vinod Ade & Milind Nisargandha · Journal of Pharmaceutical Research International · 2021

Background: In Ayurveda, Manyastambha is defined as Manyahakriyahani. It is the clinical entity in which the back of the neck becomes stiff, and the neck movement is impaired. Manyastambha is explained one of the Vataja Nanatmaja Vikara by Acharyas. Manyastambha occurs in Urdhwaj...

Open access Research Article 10.9734/jpri/2021/v33i30B31640

Traditional uses of Ethno-medicinal Plants in Chittagong Hill Tracts (CHTs), Bangladesh: A Review

Kanchan Chakma, Md. Morshedul Alam, Dhusarika Chakma & Robiul Hasan Bhuiyan · Journal of Pharmaceutical Research International · 2021

Objective: Traditional medicines are of great importance to villagers and also now a day to modern drugs. Scientists are trying to explore new drug resources along with the modern drugs to support drug treatment strategy to be more effective and merely natural. Nature is the rich...

Open access Research Article 10.9734/jpri/2021/v33i30B31642

Differences in Surgical Outcome in Near Total Thyroidectomy for Benign Nodular Goiter: A Comparison of LigaSure Vessel Sealer versus Conventional Clamp Knot Tie Technique

Shiraz Shaikh, Champa Sushel, Ahsan Ali Laghari, Qamber Ali Laghari, Zameer Hussain Laghari & Aisha Memon · Journal of Pharmaceutical Research International · 2021

Objective: To compare the efficacy of LigaSure Vessel Sealer in Near Total Thyroidectomy versus Conventional Clamp Knot Tie Technique in terms of bleeding, operative time and postoperative drainage. Methodology: This comparative cross sectional study was conducted at Department o...

Open access Research Article 10.9734/jpri/2021/v33i30B31641

Potential of Topical Cosmeceuticals Cream Functionalized with Biogenic Metallic Nanostructured Material as Antibacterial Agents

Rajesh Dodiya, Mrunal K Shirsat & Jitendra K Patel · Journal of Pharmaceutical Research International · 2021

Aims: In this study, the phytochemical analysis of Eucalyptus globulus leaf was analyzed and  used in synthesis of silver nanoparticles. The silver nanoparticle incorporated antimicrobial cosmeceutical cream was developed and characterized for physicochemical parameters, antimicr...

Open access Research Article 10.9734/jpri/2021/v33i30B31643

Protective Role of Fisetin in STZ Induced Diabetic Nephropathy in Rats

Savita Kumari, Anjoo Kamboj, Manish Wanjari & Anil Kumar Sharma · Journal of Pharmaceutical Research International · 2021

Objectives: Chronic diabetes mellitus associated with devastating complication the diabetic nephropathy, that further progress to ESRD,a major cause of morbidity and premature mortality in many countries worldwide. Accumulated evidences demonstrated that long standing hyperglycem...

Open access Research Article 10.9734/jpri/2021/v33i30B31644

Evaluation of Antibacterial Activity and GCMS Analysis of Zanthoxylum Ovalifolium Fruit Extracts

P. Pavani & Raja Naika · Journal of Pharmaceutical Research International · 2021

Herbal medicines have played a vital role in the evolution of humanity and civilization. The fruits of the plant Zanthoxylum were collected from the study field, washed, dried in the shade and powdered. Soxhlation method was used to make different solvent extract of fruit. The di...

Open access Research Article 10.9734/jpri/2021/v33i30B31634

Molecular Docking in Drug Discovery

Rani T. Bhagat, Santosh R. Butle, Deepak S. Khobragade, Sagar B. Wankhede, Chandani C. Prasad, Divyani S. Mahure & Ashwini V. Armarkar · Journal of Pharmaceutical Research International · 2021

In last few years the Computer Aided Drug Design and Discovery is many success rates. In academics and many pharmaceutical industries for drug lead discovery they adopt the Computational Drug Design. The modern era of drug discovery and development structural information play an...

Open access Research Article 10.9734/jpri/2021/v33i30B31639

Exraction of Secondary Metabolites Using Bacillus endopyticus and Its Applications

S. Kalima, K. Thanga Mariappan, Jesteena Johney & R. Ragunathan · Journal of Pharmaceutical Research International · 2021

Bacillus Species was isolated from a soil sample, the isolate was cultivated, identified and its culture medium was extracted. Specific media called Gibbon’s media used for the cultivation and confirmation of the bacteria. 16S rRNA study was done for the morphological identificat...

Open access Research Article 10.9734/jpri/2021/v33i30B31635

Effect of Yoga Basti in the Management of Sandhivata a Clinical Study

Anagha Anigol, Arun Vaidya, Prasanna Mathad & Amit Upasane · Journal of Pharmaceutical Research International · 2021

Yoga basti a type of basti explained to treat many diseases in Ayurveda when basti given for 8 days in respective diseases like Sandhivata, Janusandhi vata  and sarvanga vata.. Basti is one among the panchakarma procedure, there are many references of bastis are available in veda...

Open access Research Article 10.9734/jpri/2021/v33i30B31636

In-Hospital Outcome of Patients with Acute ST-Segment Elevation Myocardial Infarction Who Did Not Receive Reperfusion Therapy at Our Institute

Shahid Hussain Memon, Ghulam Fareed Shah, Gul Hassan Brohi, Abdul Ghaffar Memon, Jagdesh Kumar & Anwar Ali · Journal of Pharmaceutical Research International · 2021

Objective: This study aims to determine the in-hospital outcome of patients with acute ST-segment elevation myocardial infarction who did not receive reperfusion therapy at our institute. Methodology: Cohort of patients recruited from Emergency Department of Liaquat University Ho...

Open access Research Article 10.9734/jpri/2021/v33i30B31637