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All published articles 7450

Evaluation of Catalase and Manganese in Type 2 Diabetic Patients in University of Port Harcourt Teaching Hospital

Arvin Nwakulite, Emmanuel I. Obeagu, Richard Eze, C. C. N. Vincent, Ejike Felix Chukwurah, Chukwuma J. Okafor, Adaobi Maryann Ibekwe, Calista Ndidi Adike, Ufuoma Chukwuani & Bart I. Ifionu · Journal of Pharmaceutical Research International · 2021

This study was carried out to evaluate catalase and manganese in type 2 diabetes mellitus patients. A total of 40 subjects Were included in this study. This comprised of equal number of male and female subjects respectively. Enzyme linked immunosorbent assay (ELISA) method was us...

Open access Research Article 10.9734/jpri/2021/v33i30B31638

A comparative Clinical Study to Evaluate the Efficacy of Anuvasan Basti with Brahatchaglyadi Ghritam and Guggulutiktam Ghritam in the management of Gridhrasi (Sciatica): A Study Protocol

Arun Kumar Gupta, Shweta Parwe, Trupti Gupta & Milind Nisargandha · Journal of Pharmaceutical Research International · 2021

Background: Gridhrasi is such a Ruja Pradhaana Vatavyadhi. In Gridhrasi intense shooting pain characteristically radiates from Sphika (gluteal region) to Pada (foot). Based on symptoms of Gridhrasi, it can be equated with the disease sciatica in modern science. The lifetime incid...

Open access Research Article 10.9734/jpri/2021/v33i30A31623

Comparative Assessment of Kukkutanda Pinda Sweda and Patra Pinda Sweda in the Management of Manyastambha (Cervical Spondylosis) - A Study Protocol

Vivek Kumar Verma, Shweta Parwe & Milind Nisargandha · Journal of Pharmaceutical Research International · 2021

Background: At the present time, human beings are easily prone to get several degenerative disorders because of their stressful and reckless lifestyle. 'Manyastambha' is one such lifestyle disorder instigated from excessive use of vehicle, excessive travelling, continuous sitting...

Open access Research Article 10.9734/jpri/2021/v33i30A31624

A Comparative Study to Evaluate the Efficacy of Lekhana Basti and Modified Vachadi Gana Basti in Combination with Navaka Guggulu in Sthaulya (Obesity) -A Study Protocol

Amiya Bhonsle, Shweta Parwe & Milind Nisargandha · Journal of Pharmaceutical Research International · 2021

Background: Sthoulya described as Obesity occurs due to the vitiation of Kapha & Vata. The signs and symptoms of Sthoulya can be correlated with Obesity. This has been said in Ayurveda and Sthaulya purusha (Obese person) is considered one of the nindita Purusha. Lekhaniya gan...

Open access Research Article 10.9734/jpri/2021/v33i30A31626

Protocol on Comparative Clinical Efficacy of Tryushanadi Guggul and Navaka Guggul in Sthoulya (Overweight)

Ashvini Dineshrao Pardhekar, Sadhana Misar(Wajpeyi) & Vinod Ade · Journal of Pharmaceutical Research International · 2021

Background: Sthoulya is Medovaha Strotodushtijanya vyadhi, which includes abnormal and excessive accumulation of Medodhatu in the body. This is caused by lack of physical and mental activity, daytime sleep, excessive intake of madhur (sweet), snigdha ahar (oily diet) results in ...

Open access Research Article 10.9734/jpri/2021/v33i30A31628

Research Protocol for Assessment of Solitary and Combined effect of Guduchi and Punarnava on Structural and Functional Changes of Ageing in Liver and Kidney in Wistar Rats

Kalpana Tawalare, Pradnya Dandekar, Priti Desai & Kiran Tawalare · Journal of Pharmaceutical Research International · 2021

Background: The liver and kidney play a central role in metabolic and detoxification processes leads to structural degeneration of organs with aging, which may hamper the functional ability of these organs. Acharya charaka suggests to use drugs of vayasthapana mahakashaya in diff...

Open access Research Article 10.9734/jpri/2021/v33i30A31630

Androgenetic Alopecia as a Marker of Metabolic Syndrome

Faryal Hussain Memon, Abdul Ghani Rahimoon, Pardeep Kumar, Shahid Hussain Memon, Erum Siddiqui, Tarachand Devrajani, Samar Raza & Syed Zulfiquar Ali Shah · Journal of Pharmaceutical Research International · 2021

Background: Alopecia induced by androgens in genetically predisposed individuals is termed as Androgenetic alopecia (AGA). There is proof appearance the relationship between Androgenetic alopecia and metabolic condition. Objective: To determine frequency of metabolic syndrome in...

Open access Research Article 10.9734/jpri/2021/v33i30A31625

Hepatoprotective Activity of Acampe praemorsa

Praveen Kumar Uppala, G. S. N. Koteswara Rao, A. Rajasekhar Reddy, K. Umasankar, C. Joshitha, Kanagala Anusha, Nadeem Siddiqui & Sarada Prasanna Mallick · Journal of Pharmaceutical Research International · 2021

Introduction: Liver is one of major functional organ in body, its damage can alter body metabolisms and other organs’ function. So, it is very important to maintain the healthy liver. Now a days, different chemicals and inadequate use of medicines are causing liver impairments in...

Open access Research Article 10.9734/jpri/2021/v33i30A31627

Development and Validation of Direct Spectrophotometric Method for the Estimation of Glimepiride

Dilip Chafle & Lata Awale · Journal of Pharmaceutical Research International · 2021

Aims: To develop simple, sensitive and direct spectrophotometric methods for the estimation of widely prescribed antidiabetic hypoglycemic agent Glimepiride in pure and pharmaceutical dosage form. Place and duration of study: Research Centre of Taywade Group of Institution Koradi...

Open access Research Article 10.9734/jpri/2021/v33i30A31629

Development and Validation of New Analytical LC-MS/MS Method for the Estimation of Antidiabetic Drugs Ertugliflozin and Sitagliptin in Combined Pharmaceutical Dosage form

Suleman S. Khoja & Laxman J. Patel · Journal of Pharmaceutical Research International · 2021

Ertugliflozin and Sitagliptin is combination of Antidiabetic drug in tablet Steglujan 15 mg/100 mg film-coated tablets®, a member Antidiabetic drug, is a recent drug developed by Merck Sharp and Dohme Company for the treatment of Type 2 diabetes. Ertugliflozin and Sitagliptin can...

Open access Research Article 10.9734/jpri/2021/v33i30A31631

HPTLC Profile and Screening of Antimicrobial Activity of Pongamia Pinnata Pierre

Rajani Shirsat, Ajit Kengar & Aruna Rai · Journal of Pharmaceutical Research International · 2021

Aim: Plant secondary metabolites are the alternatives for the control of the antibiotic resistant pathogens which are highly infectious to human and plants. With respect to these aspects present work was carried out with phytochemical studies and antibacterial screening of Pongam...

Open access Research Article 10.9734/jpri/2021/v33i30A31632

Protocol - Assessment about Knowledge of Panchakarma in Asha Workers and their Sensitization with Panchakarma Module in Wardha Taluka

Jagruti N. Chaple & Punam Sawarkar · Journal of Pharmaceutical Research International · 2021

Background: A village level community health worker " Accredited Social Health Activist " (ASHA)’acts as a bridge between community & health care facilities. The ASHA workers act as catalysts in promoting various programmes of the foundation and encourage people to avail the...

Open access Research Article 10.9734/jpri/2021/v33i30B31633

Effective Anesthesia during Various Manipulations in Maxillofacial Surgery and in Dental Practice: Overview of Medicines

Ripsime Armenovna Davtyan, Mariya Vladimirovna Khamarova, Alexander Markov & Vitaly Viktorovich Goncharov · Journal of Pharmaceutical Research International · 2021

In the practice of modern specialists of maxillofacial surgery and dentists, the use of local anesthetics is a necessary condition for comfortable medical manipulations. Accordingly, in order to achieve the medical goals, it is necessary to make a competent choice of anesthetic m...

Open access Research Article 10.9734/jpri/2021/v33i30A31619

Impact of Foeniculum vulgare on Hemoglobin, Red Blood Cell Indices and White Blood Cell Count: A Laboratory Based Randomized Controlled Study

Afshan Abbas, Rahila Ikram, Abeer Adil, Qurrat Ul Ain Bukhari & Faiza Hasan · Journal of Pharmaceutical Research International · 2021

Aims: Anemia is prime health issue of the population in developing region of world mostly due to dietary deficiencies and poor sanitation. Supplementary medicines as well as iron rich foods are utilized to combat this problem. Herbal products also have value in such diets. We eva...

Open access Research Article 10.9734/jpri/2021/v33i30A31620