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Impact of Natural Products on Developing New Treatments for Corona Virus Disease (COVID-19): Review

Amna A. Saddiq, Enas N. Danial & Iman A. Saraf · Journal of Pharmaceutical Research International · 2021

COVID-19 is dominatingly considered as an unavoidable pandemic, and researchers are exceptionally inquisitive about how to give the best assurance to people in general before an immunization can be made accessible. Normal items have consistently assumed an essential part in drug...

Open access Research Article 10.9734/jpri/2021/v33i28B31543

Awareness of Retinopathy among Sickle Cell Patients

Shahad Alruwaili, Yasser Aleliwi, Shahd Al Mahfud, Mohammad Alshehri, Hamad Al Ghathber & Abdullah Alamri · Journal of Pharmaceutical Research International · 2021

Background: Sickle cell disease (SCD) is a haemoglobinopathy that is inherited in an autosomal recessive pattern. Retinopathy is a complication of SCD, which varies from mild peripheral retinopathy to severe proliferative retinopathy that can cause loss of vision. Methods: A cros...

Open access Research Article 10.9734/jpri/2021/v33i28B31540

Synthesis, Drug Likeness and In-vitro Screening of Some Novel Quinazolinone Derivatives for Anti-Obesity Activity

Pratik G. Modh & Laxman J. Patel · Journal of Pharmaceutical Research International · 2021

Aim: A series of novel quinazolinone derivates was synthesized and assessed for their ability to inhibitory action on pancreatic lipase. The cyclization of quinazolinone-4(3H)-one derivatives was achieved, whereas carbon-carbon cross coupling reactions were carried out on cyclize...

Open access Research Article 10.9734/jpri/2021/v33i28B31541

Comparative Study of Different Oral Iron Preparations in Females of Reproductive Age Group

Megha Tiwari, Vishal Dubey & Nikita Srivastava · Journal of Pharmaceutical Research International · 2021

Background: Anemia (anemia) is a decrease in the total amount of red blood cells (RBCs) or hemoglobin in the blood, or a lowered ability of the blood to carry oxygen. The commonness of iron inadequacy is high in all age bunch females. Around 32.4% of ladies have mellow iron defic...

Open access Research Article 10.9734/jpri/2021/v33i28B31542

Regulatory Prototype for Biological Products in the United States

G. M. Pavithra & N. Venugopal · Journal of Pharmaceutical Research International · 2021

Biological products are used for the treatment of many disease, so the biological application submitted for the approval of products are also increasing. The progress of a biosimilarproduct is more difficult and expensive than a small molecule generic product. Biosimilars are not...

Open access Research Article 10.9734/jpri/2021/v33i28B31539

Estimation of Alanine Transaminase (ALT), Alkaline Phosphate (ALP) and Aspartate (AST) Irrespective of Dietary Supplementation, Body Mass Index and Nature of Exercise

Alamgir khan, Muhammad Zafar Iqbal Butt, Abdul Manan, Ejaz Asghar, Muhammad Jamil & Samiullah khan · Journal of Pharmaceutical Research International · 2021

Purpose: This research study was conducted for the assessment of liver enzymes i.e. Alanine Transaminase (ALT), Alkaline Phosphate (ALP) and Aspartate (AST) irrespective of dietary supplementation, body mass index and nature of the exercise. Methods: A randomized control trails w...

Open access Research Article 10.9734/jpri/2021/v33i28B31536

A Randomized Control Trails for the Assessment of Impact of Moderate Intensity Exercise on Blood Serum Creatinine Concentration among the Male Athletes

Mohibullah Khan, Alamgir khan, Muhammad Zafar Iqbal Butt, Badar Mohy ud Din, Abdul Manan, Shareen Bhatti, Fakiha Wadiat & Muhammad Jamil · Journal of Pharmaceutical Research International · 2021

Purpose: The main purpose of the study was to examine the impact of moderate intensity exercise on blood serum creatinine concentration among the male. Method & Materials: A randomized control trails were conducted for purpose to evaluate the effects of moderate intensity exe...

Open access Research Article 10.9734/jpri/2021/v33i28B31537

Assessing the Medication Adherence of Metabolic Disorders in South India

P. Aravinda Swami, R. T. Saravana Kumar & S. Manohar Babu · Journal of Pharmaceutical Research International · 2021

Aim: The study's main objective was to assess patients' adherence towards treatment and daily practices among Hypertension (HT), Diabetes Mellitus (DM) Type II and hypothyroid participants in South India before and after providing counseling and education based on WHO            ...

Open access Research Article 10.9734/jpri/2021/v33i28B31538

Antiviral Potential of Medicinal Plants and Plant Lectins: Use in COVID-19 Pandemic Era

Eda Büker & Ibrahim Adnan Saraçoğlu · Journal of Pharmaceutical Research International · 2021

At the time of writing the research paper, the world is faced with an acute respiratory syndrome pandemic that is named as coronavirus 2 (SARS-CoV-2). This pandemic is also called Covid-19, is a respiratory disease based on the lungs caused by the new coronavirus the SARS-CoV-2....

Open access Research Article 10.9734/jpri/2021/v33i28A31535

Exploration of Antioxidant and Anticancer Activity of Stephania japonica Leaves Extract

Md. Dobirul Islam, Ariful Islam, Naoshia Tasnin, Syeda Farida Akter & Md. Salim Uddin · Journal of Pharmaceutical Research International · 2021

Aims: The demand for antioxidants from the natural source has drawn promising attention to outturn desired pharmacological effect by subsidizing the adverse effect for treating cancer. This study evaluated the antioxidant activity of Stephania japonica leaves extracts to explore...

Open access Research Article 10.9734/jpri/2021/v33i28A31529

Pharmacological and Toxicological Appraisal of Promising Enzyme-tyrosinase Isolated from Soil Bacteria-an Update

Asma Ahmed, Kinza Rashid Gill, Hassan Akbar Khan, Sitwat Aman, Javed Anver Qureshi & Rafia Mehmood · Journal of Pharmaceutical Research International · 2021

Aims: The membrane associated tyrosinase is an enzymatically active monomeric glycoprotein which is purified to only a low degree. It has gained importance in the present era due to its antioxidant and immunomodulatory properties as well as applications in industry. Moreover its...

Open access Research Article 10.9734/jpri/2021/v33i28A31534

Respiratory Morbidity in Neonates at or Near-Term in Relation to Mode of Delivery - A Retrospective Observational Study

Fouzia Rasool Memon, Asma Naz, Nusrat Fozia Pathan, Shahida Baloch, Ameer Ali Jamali, Fareeda Wagan & Arslan Ahmer · Journal of Pharmaceutical Research International · 2021

Introduction: Antenatal corticosteroids are recommended by Royal College of Obstetrics and Gynaecology for caesarean section planned before thirty-eight plus six weeks gestation. However, these steroids are, not suggested for labour induced electively after thirty four weeks. Obj...

Open access Research Article 10.9734/jpri/2021/v33i28B31530

Topical Delivery of Apremilast Loaded Nanostructured Lipid Carrier Based Hydrogel for Psoriasis Therapy

S. M. Sindhoor & Marina Koland · Journal of Pharmaceutical Research International · 2021

Background: Apremilast (APR) is an orally administered selective phosphodiesterase 4 inhibitor approved to treat plaque psoriasis and psoriatic arthritis and is available as an oral tablet formulation. However, its systemic side effects limit its application. The low solubility a...

Open access Research Article 10.9734/jpri/2021/v33i28B31531

Risk Factors during Pregnancy for Asymptomatic Bacteriuria

Sikander Ali Sial, Amir Bux Detho, Fouzia Rasool Memon, Kousar Parveen, Shabana Memon, Sadia Bukhari & Arslan Ahmer · Journal of Pharmaceutical Research International · 2021

Introduction: Asymptomatic bacteriuria in pregnancy (ABU) is poorly understood and neglected in developing countries. It causes certain lethal maternal and fetal consequences if left untreated including low weighted births, premature delivery, full-blown urinary tract infection a...

Open access Research Article 10.9734/jpri/2021/v33i28B31532

Postoperative Complications of Conventional Polypectomy Versus Endoscopic Sinus Surgery

Arsalan Ahmed Shaikh, Mona Liza Mahesar, Noman Ahmed, Sajjad Yousuf, Akhtar Ali Lakhiar & Farhan Ahmed Shaikh · Journal of Pharmaceutical Research International · 2021

Objective: To compare the postoperative complications of conventional polypectomy versus Endoscopic sinus surgery. Study Design: This is cross sectional study. Setting: Study carried out at E.N.T department, Tertiary care hospital from April 2019 - March 2020. Materials & Met...

Open access Research Article 10.9734/jpri/2021/v33i28B31533