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All published articles 7450

Formulation, Optimization and Evaluation of Ion Triggered Ophthalmic in Situ Gel

Amol Tagalpallewar, Prajvita Rai, Satish Polshettiwar, Wani Manish & Akshay Baheti · Journal of Pharmaceutical Research International · 2021

Topical eye drop is the convenient and patient compliant route of drug administration, particularly for the treatment of anterior part diseases. Transport of drugs to the targeted ocular tissues is limited by various precorneal, active and stationary ocular barriers. The aim of d...

Open access Research Article 10.9734/jpri/2021/v33i28A31511

One Size Does Not Fit All: An Overview of Personalized Treatment in Cancer

Sohini Kulavi, Chandreyi Ghosh, Moumita Saha & Sirshendu Chatterjee · Journal of Pharmaceutical Research International · 2021

The last few decades have witnessed 'one size fits all' kind of conventional treatment strategy i.e. a similar line of treatment or usage of the same drug to treat a particular disease. This approach is not associated with specific personal characteristics but with individual gen...

Open access Research Article 10.9734/jpri/2021/v33i28A31513

Studies on Pancreatic Gene Expression in Diabetic Rats Treated with Moringa oleifera Leaf

Arvin Nwakulite, Emmanuel Ifeanyi Obeagu, H. U. Nwanjo, D. C. Nwosu, I. N. Nnatuanya, C. C. N. Vincent, Chukwudi Ofodile Amaechi, Ogochukwu, Mary-Theodora Barbara Ochiabu, Adaobi Maryann Ibekwe, Chukwuma J. Okafor, Getrude Uzoma Obeagu & Nkiruka Millicent Amadi · Journal of Pharmaceutical Research International · 2021

Moringa oleifera leaf have been used for treatment of diabetes, in this work we studied pancreatic gene expression. The gene expression was done by PCR machine. The plant was harvested from garden within Madonna University and was identified in the Department of Pharmacognosy of...

Open access Research Article 10.9734/jpri/2021/v33i28A31512

Determinination of the Frequency of Altered Cardiac Repolarization by Measuring the Heart rate Corrected QT Interval in COPD Patients

Shahla Roshan Memon, Muhammad Aslam Rind, Maria Nazir, Shah Jehan Memon & Muhammad Saleem Rind · Journal of Pharmaceutical Research International · 2021

Objectives: To determine the frequency of altered cardiac repolarization by measuring the heart rate corrected QT interval in COPD patients. Setting: Department of Medicine at LUMHS hospital Hyderabad/Jamshoro. Study Design: Descriptive Cross sectional study.          Duration of...

Open access Research Article 10.9734/jpri/2021/v33i28A31514

An Overview of Different Methods for Aminoglycoside Residue Determination

Sarah Morovatdar, Bahman Khameneh, Zahra Khashyarmanesh & Bibi Sedigheh Fazly · Journal of Pharmaceutical Research International · 2021

Aminoglycosides (AGs) are chemical substances that exist in the bacteriologic category of traditional antibiotic (AB) therapy. The importance of the determination of AG as has been described in many situations by researchers. Because of the narrow therapeutic ranges of AGs, consi...

Open access Research Article 10.9734/jpri/2021/v33i28A31506

Hepatitis C Treatment by Directly Acting Antiviral Agents and Its Impact on Glycemic Control

Darshan Kumar, Ahsan Mobin, Hafeezullah Shaikh, Syed Mohammad Kashif, Zunaira Nawaz, Muhammad Arif Iqbal & Ubedullah Shaikh · Journal of Pharmaceutical Research International · 2021

Objective: To evaluate Hepatitis C treatment by directly acting antiviral agents and its impact on glycemic control.            Study Design: This is an observational study. Setting: This study was conducted in Medicine department Civil Hospital Karachi from March 2018 to Decembe...

Open access Research Article 10.9734/jpri/2021/v33i28A31507

Diabetes Mellitus: An Overview and Management with Herbs

Ghazala Shaheen, Iqra Fatima, Raessa Noor, Muhammad Younus, M. Sajid-Ur-Rehman, Saira Ghaffar, Shafqat Rasool, Farah Zafar & Mohsin Abbas Khan · Journal of Pharmaceutical Research International · 2021

Diabetes mellitus (DM) could be a typical disturbed throughout the globe. As of late, there are changed sorts of examinations and overview works region units considered. The individuals' Republic of Pakistan is that the place where there is magnificence while the common plants ha...

Open access Research Article 10.9734/jpri/2021/v33i28A31509

Interaction System of the State and Business in the Regime of Public-Private Partnership in the Pharmaceutical Complex of the Russian Federation

Natalia S. Klunko & Anastasia E. Lobanova · Journal of Pharmaceutical Research International · 2021

The issue of interaction between the state and business in the mode of public-private partnership in the pharmaceutical complex of the Russian Federation is investigated. The concept of "state" and "business" is defined, the forms of interaction between the state and business are...

Open access Research Article 10.9734/jpri/2021/v33i27B31498

Protective Effects of Alcoholic and Aqueous Extracts of Lyophilized Kiwifruit on Acute Kidney Injury (AKI) Induced by Glycerol in Male Albino Rat

Rawiyah M. Hakami, Fares K. Khalifa & Asmaa A. Alharbi · Journal of Pharmaceutical Research International · 2021

Objectives: The study aimed to evaluate and compare the protective effects of alcoholic and aqueous extracts of lyophilized kiwifruit on acute kidney injury (AKI) induced by glycerol in male albino rats. Methods: Rats were divided into four groups: negative control healthy group,...

Open access Research Article 10.9734/jpri/2021/v33i27B31499

To Evaluate the Frequency of Diabetes Mellitus Patients with Hepatitis C at Tertiary Hospital of Sindh, Pakistan

Kuldeep Kumar Mewaram, Faraz Qurban Rajper, Khalida Unar, Mirza Tasawar Baig & Ayaz Ali Unar · Journal of Pharmaceutical Research International · 2021

Objective: The major theme of the research was to evaluate the frequency of diabetes mellitus patients with hepatitis C infection at tertiary care hospital of Sindh, Pakistan. Methodology: Descriptive cross sectional study was conducted at tertiary care hospital of Sindh, Pakista...

Open access Research Article 10.9734/jpri/2021/v33i27B31500

Evaluation of Drug Resistance and Treatment Outcomes among TB Patients with Diabetes Mellitus at Tertiary Care Hospital of Sindh, Pakistan

Kahaf Khan, Ayaz Ali Unar, Khalida Unar, Faraz Qurban Rajper & Mirza Tasawar Baig · Journal of Pharmaceutical Research International · 2021

The objective of the study is to evaluate of drug resistance and treatment outcomes among tuberculosis patients with diabetes mellitus at tertiary care hospital of Sindh, Pakistan.  Tuberculosis (TB) is considered as very dangerous infectious disease caused by Mycobacterium tuber...

Open access Research Article 10.9734/jpri/2021/v33i27B31501

Comparitive Study of Bactrial Flora among Diabetic and Nondiabetic Perimenopausal and Postmenopausal Women

T. Sukanya & . Yuvarani · Journal of Pharmaceutical Research International · 2021

Bacterial vaginal infections are one of the least understood infections in perimenopausal and postmenopausal age group. This is the cross sectional study undertaken done to determine the prevalence of bacterial flora perimenopuasal and postmenopausal diabetic and non diabetic wom...

Open access Research Article 10.9734/jpri/2021/v33i27B31502

Pharmacognostical Standardization, Chromatograhic and Spectral Analysis of Methanolic Extract of Echinops echinatus Linn. Roots and Fractions

Muhammad Younus, Farrakh Zia Khan, Muhammad Mohtasheem ul Hasan, Jafir Hussain Shirazi, Qazi Adnan Jamil, Zahid Khan, Ghazala Shaheen, Muhammad Hanif, Muhammad Abuzar Ghaffari, Muhammad Abdullah & Imran Nazir · Journal of Pharmaceutical Research International · 2021

Echinops echinatus Linn. (Fam. Asteraceae) possesses medicinal value a good deal. The plant is a nerve tonic that stimulates liver and increases appetite, and is effective as anti-inflammatory and in jaundice. Objective of the current study was to standardize  Echinops echinatus...

Open access Research Article 10.9734/jpri/2021/v33i27B31503

Formulation Evaluation and In- Vitro Antioxidant activity of Microparticles of Syzygium Cumini Plant Extract

Sweta Srivastava Koka, Pravin Kumar Sharma, Vaishali Sharma, Jaya verma & G. N. Darwhekar · Journal of Pharmaceutical Research International · 2021

Sygygium cumini, commonly known as Malabar plum, Java plum, black plum, jamun or jambolan, is an evergreen tropical tree in the flowering plant family Myrtaceae. The present study the antioxidant effects of microparticles of S. cumini plant extract were evaluated using in vitro,...

Open access Research Article 10.9734/jpri/2021/v33i27B31504

Neurotoxic Assessment of Chronic Abuse of Pregabalin in Wistar Rats

Neveen A. Salem, Amani M. Alsaedi, Bedor G. Alasmari, Razan Z. Almarghalani, Shahad M. Algobe & Nahd H. Alesawy · Journal of Pharmaceutical Research International · 2021

Pregabalin (Lyrica) is an analog of the gamma-aminobutyric acid neurotransmitter,   approved for the treatment of epilepsy, generalized anxiety disorder, neuropathic pain, and fibromyalgia. The possibility for abuse and/or dependence on pregabalin has risen recently. Pregabalin i...

Open access Research Article 10.9734/jpri/2021/v33i27B31505