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Significance of ISO 10993 Standards in Ensuring Biocompatibility of Medical Devices: A Review

Akash Sharma & Gaurav Luthra · Journal of Pharmaceutical Research International · 2023

This review paper aims to highlight the crucial role of ISO 10993 standards in ensuring the biocompatibility of medical devices. The use of medical devices has increased rapidly over the years, and it is essential to ensure that these devices do not cause adverse reactions or har...

Open access Research Article 10.9734/jpri/2023/v35i87342

Remineralization of Tooth: A Literature Review

Samandeep Kaur, Sunil Gupta, Manjul Mehra, Gunmeen Sadana, Teena Gupta & Rashu Grover · Journal of Pharmaceutical Research International · 2023

Non-cavitated carious lesions are managed non-invasively through remineralization in an attempt to prevent disease progression, and to improve strength, esthetics, and function of teeth in the modern dentistry. The emphasis presently is being given to new technologies which sugge...

Open access Research Article 10.9734/jpri/2023/v35i87341

The Wound Healing Potential of 2,3 Dimethylquinoxaline Hydrogel in Rat Excisional Wound Model

Abdelbagi Elfadil, Ahmed S. Ali, Mohammad W. Alrabia, Hamoud Alsamhan, Hind Abdulmajed, Ibrahim Ismail Mohammed Abu, Mohammad Allibaih & Khalid Hussein Bakheit Ahmed · Journal of Pharmaceutical Research International · 2023

Background: 2,3-dimethylquinoxaline (DMQ) is a naturally occurring compound with documented antifungal activity. It showed also good in vitro physicochemical and pharmacokinetic characteristics. Methods: The wound healing activity of 1% DMQ hydrogel in healthy adult male Wister r...

Open access Research Article 10.9734/jpri/2023/v35i87339

Tapentadol Nasal Spray is an Effective Way of Pain Management after Tooth Extraction: A Randomized Control Clinical Trial

Md. Khizar Hussain Mazhari, JAGADISH CHANDRA & Joyce P. Sequeira · Journal of Pharmaceutical Research International · 2023

Background: Tapentadol nasal spray (Tapease NS) application is a novel method of pain management attributable to its action on higher centers for pain management in contrast to non-steroidal analgesics. The study aims to compare the efficacy of post-extraction pain control betwee...

Open access Research Article 10.9734/jpri/2023/v35i87340

Incidence of Perineural Invasion of Oral Squamous Cell Carcinoma and Its Association with Worst Pattern of Invasion and Staging of Tumor: A Retrospective Study

Aamir Zubair Shaikh, JAGADISH CHANDRA, Joyce P. Sequeira, Madan K. & Rohan T. Mathew · Journal of Pharmaceutical Research International · 2023

Background: Histological parameters are the most reliable factors in diagnosis, management and prognosis of oral squamous cell carcinoma (OSCC). The incidence of perineural invasion (PNI) and its association with staging of tumor and worst pattern of invasion (WPOI) have influenc...

Open access Research Article 10.9734/jpri/2023/v35i77337

In-Vitro Antioxidant, Anti-Arthritis, Anti-inflammatory, Thrombolysis, Anti-bacterial, and in-Vivo Neuropharmacological Activities of Bioactive Metabolites of Solanum americanum Mill.

Hasib Khan Shomudro, Anan Mahabub Aboni, Tasbira Jasmeen & Sherejad Sanam · Journal of Pharmaceutical Research International · 2023

Aims: The purpose of this research was to examine the effects of methanol-prepared leaf extracts from the Solanum americanum Mill. plant on a variety of in vitro activities, including antioxidant, anti-Arthritis, anti-inflammatory, thrombolysis, anti-bacterial, and in-vivo neurop...

Open access Research Article 10.9734/jpri/2023/v35i77338

A Case Report of Brain Metastases after Neoadjuvant Chemo and Radiotherapy for Esophagogastric Junction Adenocarcinoma in an Adult Male Patient

Fu Zhi Jun, Wu Wen Long, Muhammad Abbas, LI Shu Guang, Bi Ren Jie & Cao Ming Fu · Journal of Pharmaceutical Research International · 2023

Background: Treatment given as a first step to shrink a tumor before the main treatment, which is usually surgery, is given. Examples of neoadjuvant therapy include chemotherapy, radiation therapy, and hormone therapy. It is a type of induction therapy. The most common pattern of...

Open access Research Article 10.9734/jpri/2023/v35i77336

Evaluation of Efficacy of Ultrasound Therapy as an Adjuvant in Management of Myofascial Pain: A Randomized Clinical Trial

Harini Valluri, Rakesh Kumar Manne, N. Kannan, P. Venkata Sarath, B. Swapna Sridevi & Sravya Vemareddy · Journal of Pharmaceutical Research International · 2023

Aims: To determine ultrasound therapy as an effective adjuvant for the management of myofascial pain involving masticatory muscles. Study Design: Randomized clinical trial study. Place and Duration of Study: Department of oral medicine and radiology, Narayana dental college and h...

Open access Research Article 10.9734/jpri/2023/v35i77334

Green Synthesis and Characterization of Copper Oxide Nanoparticles Using Tecoma Stans

Manivannan Rangasamy, Suresh Kumar Gopal, A. Indhumathi, S. Loganathan, S. Manikandan & R. Naresh · Journal of Pharmaceutical Research International · 2023

Aims: An eco-friendly approach utilizing biologically-mediated processes has been developed for the fabrication of CuO nanoparticles using Tecoma stans leaves. Methodology: The synthesis of CuO nanoparticles was carried out using an environmentally friendly method, which involved...

Open access Research Article 10.9734/jpri/2023/v35i77335

Reprofiling Hydrogen Peroxide from Antiseptics to Pyolytics: A Narrative Overview of the History of Inventions in Russia

Aleksandr Urakov, Natalya Urakova, Alexey Reshetnikov, Albina Shchemeleva, Petr Shabanov, Lubov Lovtsova, Aleksandr Samorodov, Evgeny Fisher, Anastasia Stolyarenko, Daria Suntsova, Ilnur Yagudin & Nikita Muhutdinov · Journal of Pharmaceutical Research International · 2023

Pyolytics are drugs that dissolve thick pus when applied topically. This group of drugs was discovered in early 21st century in Russia as a result of successful repurposing of antiseptics hydrogen peroxide, sodium bicarbonate and sodium chloride from antiseptics to pyolytics. Pri...

Open access Research Article 10.9734/jpri/2023/v35i67333

A Comparative Study of Plastic and Conserving Surgery in Surgical Treatment for Breast Cancer

Muhammad Abbas, LI Shu Guang, Fu Zhi Jun, Wu Wen Long, Zeeshan Bashir & Shahid Moin Qureshi · Journal of Pharmaceutical Research International · 2023

Objective: Tumor surgeons now pay special attention to the alteration in breast form following breast-conserving surgery. Safety of breast-conserving margins and postoperative breast appearance are typically challenging in conventional breast-conserving surgery due to the effect...

Open access Research Article 10.9734/jpri/2023/v35i67331

Acute Pancreatitis- A Lesser-known Complication of Celphos Poisoning- A Case Report

Rohit Raina, Vikram Jain, Nonita Thokchom, Mayank Agarwal, Vinod Gupta, Dipesh Jha & Monika Pathania · Journal of Pharmaceutical Research International · 2023

Aluminium phosphide is used to control rodents and pests in grain storage facilities. It is readily available as a fumigant for stored cereal grains and sold under various brand names such as QuickPhos, Salphos and Celphos. It acts by causing cellular hypoxia by its effect on mit...

Open access Research Article 10.9734/jpri/2023/v35i67332

A Comprehensive Review of Risk Management in the Medical Device Industry

Akash Sharma & Gaurav Luthra · Journal of Pharmaceutical Research International · 2023

The medical device industry is highly regulated, with a focus on ensuring the safety and effectiveness of medical devices. Risk management is a critical aspect of the medical device industry, involving the identification, assessment, and control of potential risks associated with...

Open access Research Article 10.9734/jpri/2023/v35i67330

Development and Validation of UV-Spectroscopic Method for Simultaneous Estimation of Metformin Hydrochloride and Pravastatin Sodium

Ankita Sharma, Kapil Kumar Verma, Inder Kumar, Anju Bala, Bhumika Thakur & Vandana Thakur · Journal of Pharmaceutical Research International · 2023

Introduction: A new, simple, precise, accurate, and reproducible method was developed and validated for the simultaneous estimation of Metformin Hydrochloride (MH) and Pravastatin Sodium (PS) in pure form. Methodology: Simultaneous estimation of Metformin Hydrochloride (MH) and P...

Open access Research Article 10.9734/jpri/2023/v35i67329

Spectrophotometric Analysis of Variation of Fluoride Content in Dentifrices – A Quantitative Study

Akshaya Mudaliar, Mansi Baviskar, Sanjana R. Kodical, Chinmaya Chaudhary & Aayushi Mehta · Journal of Pharmaceutical Research International · 2023

Background: A dentifrice and a toothbrush are universal armamentariums for oral hygiene maintenance. The presence of fluoride in commercial dentifrices aids in dental caries prevention. The fluoride content and compound are mentioned on the packaging along with the time of manufa...

Open access Research Article 10.9734/jpri/2023/v35i57327