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All published articles 7450

Antibacterial and Antifungal Activity of Ficus carica Plant Extract

Firza Shafique, Uzma Naureen, Annam Zikrea, Qurban Ali, Rumana Sadiq, Mehwish Naseer, Tanzila Rafique & Sohail Akhter · Journal of Pharmaceutical Research International · 2021

The development of antibiotic resistant bacteria causes many harmful effects on human and animal lives. In developing countries many expensive synthetic drugs are being used to cure diseases but they have many side effects. Therefore, there is need to develop new strategies to co...

Open access Research Article 10.9734/jpri/2021/v33i1831311

The Role of Immune-related NLR Pyrin Domain Containing 2 (NLRP2) Gene in the Development and Diseases

Fatemah Basingab, Asmaa Alghamdi, Safiah Alhazmi, Aisha Alrofaidi & Mona Alharbi · Journal of Pharmaceutical Research International · 2021

The Nucleotide-binding oligomerization domain, Leucine-rich Repeat, and Pyrin domain-containing (NLRP) family, including NLR Family Pyrin Domain-Containing 2 (NLRP2) gene, is defined as a critical element in regulating both apoptosis and inflammation. Although the NLRP2 protein i...

Open access Research Article 10.9734/jpri/2021/v33i1831312

Prevalence of Antibiotic Use and Factors Associated With Self-medication among University Students in Malaysia

Ibrahim Mohamed Ali, Sami Mohammed Albawani, Rasheed Abdulsalam & Abdulmutalib Alabeed Allaq · Journal of Pharmaceutical Research International · 2021

Self-medication with antibiotics is a global menace especially in developing countries due to lack of knowledge, poor access to the proper health care, and the weakness in the government’s role in monitoring and controlling the use of antibiotics. Thus, this study was carried out...

Open access Research Article 10.9734/jpri/2021/v33i1831313

Healthcare Professionals (Nurses') Perceived Stress and Coping: Amid COVID-19

Fatmah J. Alsolami, Pushpamala Ramaiah, Nahla A. Tayyib, Mohammad S. Alshmemri, Sanaa A. Alsulami, Grace Lindsay & Hayam I. Asfour · Journal of Pharmaceutical Research International · 2021

Background: Nurses are the frontline health professional more likely to undergo various stressors during the pandemic Covid-19 situation. The ongoing unprecedented crisis causes more stress, especially among nurses, as they are the most vulnerable group who predominantly get impa...

Open access Research Article 10.9734/jpri/2021/v33i1831314

Perinatal Outcome in Twin Pregnancy at Khaipur Medical College, Khairpur Mirs, Pakistan

Nusrat Fozia Pathan, Shazia Jamali, Maqsood Ahmed Siddiqui, Khushi Muhammad Sohu, Ameer Ali Jamali, Asma Naz & Arslan Ahmer · Journal of Pharmaceutical Research International · 2021

Objective: To determine the perinatal outcome of twin pregnancy and to find out the frequency of twin deliveries in hospital based population. Study Design: Descriptive case series. Place and Duration of Study: The study was conducted over a period of 02 Year 1st January 2018 to...

Open access Research Article 10.9734/jpri/2021/v33i1831315

Design of Guggul Lipid Loaded Chitosan Nanoparticles Using Box-Behnken Design – An Evaluation Study

B. R. Srinivas Murthy, Prasanna Raju Yelavarthi, N. Devanna & D. Jamal Basha · Journal of Pharmaceutical Research International · 2021

Aim: Guggul lipid, a lipophillic antihyperlipidemic moiety, undergoes extensive first-pass metabolism and has low bioavailability. In order to address this limitation, guggul lipid loaded chitosan nanoparticles (GNPs) were designed, optimized and processed by 3- factor 3- level B...

Open access Research Article 10.9734/jpri/2021/v33i1831316

A Comparative Study on In-vitro Quality Control Parameters of Different Brands of Loratadine Tablets Commercially Available in Bangladesh

Rosy Fatema, Sumaiya Khan, A. S. M. Roknuzzaman, Ramisa Anjum & Nishat Jahan · Journal of Pharmaceutical Research International · 2021

Loratadine, a second generation H1-receptor antagonist, works by blocking the action of histamine and is widely prescribed for itching, runny nose, watery eyes, and sneezing from "hay fever" and other allergic conditions. To ensure quality the main requirements for a medicinal pr...

Open access Research Article 10.9734/jpri/2021/v33i1731307

Prevalence and Risk Factor of Gastro-esophageal Reflux Disease among Hail Population, Saudi Arabia

Mohammed Kuddus, Hadi Abdulaziz Aldarwish, Ali Ahmed Al Tufaif, Mohammed Ahmed Al-Tufaif & Ali Howaidi Alharbi · Journal of Pharmaceutical Research International · 2021

Aims: Gastroesophageal reflux disease (GERD) is a common gastrointestinal disorder that develops when the contents of the stomach reflux into the esophagus due to large hiatal hernia or lower esophageal sphincter dysfunction. The common symptoms of the disease include heartburn a...

Open access Research Article 10.9734/jpri/2021/v33i1731308

Pharmacokinetics Evaluation of Acamprosate Tablets in Healthy Human Volunteers

Kiran S. Chaudhari, Milind Bagul & Ketan Shah · Journal of Pharmaceutical Research International · 2021

Pharmacokinetic data of acamprosate tablets was not accessible on large number of human. Rationale to examine the pharmacokinetic properties of acamprosate calcium in healthy male subject, on single or multiple dosage administration, to evaluate the bioequivalence of two formulat...

Open access Research Article 10.9734/jpri/2021/v33i1731310

Considerations in Real-time Reverse Transcription Polymerase Chain Reaction (rRT-PCR) for the Detection of SARS-CoV-2 from Nasopharyngeal Swabs

Priyadharshini Sekar, Godfred Antony Menezes, Pooja Shivappa, Biji Thomas George & Ashfaque Hossain · Journal of Pharmaceutical Research International · 2021

Coronavirus Disease 2019 (COVID-19) was first reported in December 2019, in the City of Wuhan, China. Within the span of a few weeks, the disease had spread to other regions of China and eventually to different parts of the world. COVID 19 has affected 221 countries and territori...

Open access Research Article 10.9734/jpri/2021/v33i1731309

Method Development and Validation of Anabasine and Nornicotine in Human Plasma by LC-MS/MS

P. Rajagopaludu, N. Saritha, N. Devanna & M. Srinivas · Journal of Pharmaceutical Research International · 2021

Aim: For the Method development and validation of Anabasine and Nornicotine in human plasma LC-MS/MS technique is used. Methodology: Operated in positive electron spray ionization which removes the hardness in ions. Metoprolol is used as an internal standard. Mass analyzers are u...

Open access Research Article 10.9734/jpri/2021/v33i1731301

The Effect of Single Bout of Competitive Training on Muscle Damage and Liver Enzymes in University Student Wrestling and Taekwondo Athletes

Muhammed Emre Karaman, Cengiz Arslan & Ayşe Eda Kinaci · Journal of Pharmaceutical Research International · 2021

Aims: The effects of exercise/training on biochemical parameters may vary according to the characteristics of individuals, physical conditions, duration and intensity of exercise, and different lipid values. The purpose of this study was to investigate the alterations in muscle d...

Open access Research Article 10.9734/jpri/2021/v33i1731304

One Factor SEM and Multilevel SEM Model for Patient Satisfaction Data

Rehan Ahmad Khan Sherwani, Sajjad Ali Gill, Shaukat Ali Raza, Shumaila Abbas, Muhammad Farooq, Sana Saeed & Hira Shahid · Journal of Pharmaceutical Research International · 2021

Structural equation models are very common in medical, social, management and behavioral sciences where researchers established some causal relations between observed variables and latent variable. In structured populations the assumption of independence of observations is often...

Open access Research Article 10.9734/jpri/2021/v33i1731306

Doses of Са2+, Mg2+, K+, Nа+, Mn2+ and Zn2+ in Mountain Spring and Mineral Waters in Hydration Reaction During Sport Training and Recovery; Combination with Vitamins

Ignat Ignatov, Mariana Angelcheva & Ivan Angushev · Journal of Pharmaceutical Research International · 2021

The human body consists of 55-60% water in the case of young adults. There are numerous studies conducted in the 21st c. concerning hydration reaction in sports training and recovery. Dehydration is a natural process during training and competition. Athletes lose both water and m...

Open access Research Article 10.9734/jpri/2021/v33i1631299