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All published articles 7450

Assessing the Awareness, Attitude, and Knowledge of Senior Pharmacy Students in Jordanian Universities Regarding Antibiotic Use and Resistance: A Study of the Medical Curriculum

Ruba Malkawi, Baraa Jarwan & Jawad Tawalbeh · Journal of Pharmaceutical Research International · 2023

Inappropriate antibiotic usage is a critical issue in many countries, especially in low- and middle-income countries, where access to antibiotics may be easier but proper prescribing and use practices are often lacking. This can contribute to the development of antibiotic resista...

Open access Research Article 10.9734/jpri/2023/v35i57328

Acute Toxicity and In vivo Antioxidant Activity Evaluation of Aqueous Extracts from Phyllanthus odontadenius Müll. Arg.

Rufin Kikakedimau Nakweti, Oscar Nsendo Mwangu-Kabi, Désiré Musuyu Muganza, Richard Cimanga Kanyanga & Sébastien Luyindula Ndiku · Journal of Pharmaceutical Research International · 2023

Aims: Phyllanthus odontadenius is one of medicinal plants from Phyllanthus genus traditionally used for treatment of a good number diseases including malaria. As indeed for any other drug, P. odontadenius could present risks of intoxication for users. This study aims to evaluate...

Open access Research Article 10.9734/jpri/2023/v35i57326

Tyrosinase Inhibition, Antioxidant and Antibacterial Activity of Commercial Daisy Extract (Bellis perennis)

Enida Karić, Emir Horozić, Saša Pilipović, Esmeralda Dautović, Merima Ibišević, Amra Džambić, Semir Čeliković & Arnela Halilčević · Journal of Pharmaceutical Research International · 2023

Extracts obtained from plant material have widely applied in the chemical and pharmaceutical industries because they contain significant concentrations of biologically active substances. Commercial daisy extract (Bellis perennis) was used in this paper for in vitro testing of tyr...

Open access Research Article 10.9734/jpri/2023/v35i57325

Anti-Inflammatory Activity Evaluation of the Extract and Topical Pre-Formulation of Morus nigra Fruits

Isabel Patricia Rojas, María Elizabeth Balderrama Coca, Josefina Villagra, Gabriela Del Carmen Bejarano, Nancy Roxana Vera & Marcos Adrián Reynoso · Journal of Pharmaceutical Research International · 2023

Natural products are often a source for bioactive compounds which have great potential for developing novel therapeutic agents. In this sense, the present study aimed to formulate and evaluate a gel containing Morus nigra leaf extract and to evaluate its anti-inflammatory (in-viv...

Open access Research Article 10.9734/jpri/2023/v35i57324

Protective Effect of Lycopene Rich Tomato Puree on the Development of Atherosclerosis/Heart Diseases in Animal Models

Kavita Mane & Vasant Pawar · Journal of Pharmaceutical Research International · 2023

Background: Lycopene as an aliphatic carotenoid promulgated from tomato has gained the attention of new generation food and pharma scientists on the ground of its nutraceutical efficacy. It is a preeminent antioxidant known for its singlet oxygen quenching ability that reduces ox...

Open access Research Article 10.9734/jpri/2023/v35i47323

A Promising Analytical Method has been Crafted, Validated, and Quantified for Estimating Theophylline Utilizing UV Spectroscopic and RP-HPLC Techniques in Conjunction with Stress Degradation Studies to Pinpoint Deterioration

Chundru Sai Madhavi, Sumanta Mondal, Subhadip Chakraborty, Deyasini Saha & Prasenjit Mondal · Journal of Pharmaceutical Research International · 2023

Introduction: The current study aimed to develop and assess UV-spectrophotometric (zero order, first order, second order, area under the curve) and RP-HPLC methods for estimating theophylline in its pharmaceutical dosage form. Methods: A less toxic solvent composition of acetonit...

Open access Research Article 10.9734/jpri/2023/v35i47322

Determination of the Anti-inflammatory and Anti-microbial Activity of a Cosmetic Product Silver Stop® Cream

Zhechko P. Dimitrov, Teodora P. Popova, Irina M. Gotova, Ignat Ignatov, Teodora Todorova, Toshka E. Petrova & Fabio Huether · Journal of Pharmaceutical Research International · 2023

The anti-inflammatory and antimicrobial effects of a cream containing extracts of African geranium (Pelargonium sidoides DC.), black elderberry (Sambucus nigra L.) and St. John's wort (Hypericum perforatum L.) in colloidal nanosilver (AgNPs) at a concentration of 30 ppm, denoted...

Open access Research Article 10.9734/jpri/2023/v35i47321

An Overview of the Importance of Fogging Disinfection Method in the Healthcare Setups

Akash Sharma, Nishant Sharma & Gaurav Luthra · Journal of Pharmaceutical Research International · 2023

The medical device industry is a critical sector that plays a vital role in healthcare delivery. Due to the nature of the work, medical device facilities are at risk of contamination from harmful microorganisms. Fogging is an essential method of disinfection that is used to eradi...

Open access Research Article 10.9734/jpri/2023/v35i47319

Pharmacognostic Screening and Antimalaria Activity of Methanol Bark Extract of Daniellia oliveri (ROLFE) Hutch. & Dalz. [Fabaceae] Extract on Plasmodium berghei Infected Mice

Mba Theodora C., Amadi Chidera, Uchenna Estella & Chukwuma Micheal Onyebulam · Journal of Pharmaceutical Research International · 2023

Introduction: Malaria parasite infection has remained a global leading cause of death and disability in which about 50% of the world population is estimated to be at risk, especially in low and middle income countries. Aim: This research is designed to evaluate the pharmacognosti...

Open access Research Article 10.9734/jpri/2023/v35i47320

In vitro and In vivo Study of the Red Dragon Fruit Peel (Hylocereus polyrhizus) Methanolic Extract Gel Effect on Acne

Christin Debora Bukit, I. Nyoman Ehrich Lister & Edy Fachrial · Journal of Pharmaceutical Research International · 2023

Aim: To determine the effectiveness of Anti-Acne from the methanol extract of dragon fruit peel (Hylocereus polyrhizus) by In vitro and In vivo assay. Methods: This study was an experimental study using disc diffusion and microdilution methods as in vitro methods. Meanwhile, the...

Open access Research Article 10.9734/jpri/2023/v35i37318

Stabilization of a Pickering Emulsion by Nanoparticles of Eudragit RSPO and Pol-epsilon Caprolactone: Contact Angle Measurement and Surface Tension Studies

Sidy Mouhamed Dieng, Papa Mady SY, Mamadou Soumboundou, Alphone Rodrigue Djiboune, Ahmédou Bamba Koueimel Fall, Mamadou Niass, Moussa Diop, Louis Augustin Diagua Diouf, Gora Mbaye & Mounibé Diarra · Journal of Pharmaceutical Research International · 2023

The use of colloidal particles to prepare and stabilize emulsions, known as "Pickering emulsions “, has aroused growing interest in recent years. Pickering and Ramsden demonstrated at the beginning of the last century the feasibility of surfactant-free emulsions, in presence of t...

Open access Research Article 10.9734/jpri/2023/v35i37317

Comparative Quality Analysis of Three Marketed Melatonin Containing Products in Spain for the Improvement of Sleep

Ana María Castilla Olea, Jaime de Algorta, Idoia Arriaga-Ibañez, Ilia Villate-Beitia, Idoia Gallego, Çağla Defterali & Jose-Luis Pedraz · Journal of Pharmaceutical Research International · 2023

Background: Exogenous melatonin may effectively improve the sleep-wake cycle and sleep quality in subjects with age or disease related decrease in endogenous melatonin production or response. A controlled release melatonin-based medication, Circadin® has been developed and licens...

Open access Research Article 10.9734/jpri/2023/v35i37316

A Case Report on Congenitally Absent Bilateral Maxillary Primary and Permanent Lateral Incisors

Rashu Grover, Sumedha Chhibber, Manjul Mehra, Gunmeen Sadana, Sunil Gupta & Teena Gupta · Journal of Pharmaceutical Research International · 2023

Hypodontia is uncommon in the deciduous dentition with a prevalence that ranges from 0.5% to 0.9%, with the maxillary lateral incisor being the most affected unilaterally or bilaterally.This paper reports a case of a 6 year old female with the chief complaint of missing teeth in...

Open access Research Article 10.9734/jpri/2023/v35i37314

Development of New Generation Drugs by Enriching Them with Gases

Aleksandr Urakov, Petr Shabanov & Lubov Lovtsova · Journal of Pharmaceutical Research International · 2023

Until today, the mechanism of action of drugs is traditionally considered without taking into account the physical-chemical properties of dosage forms. However, at the beginning of the 21st century, there were reports that all drugs contain unaccounted gases that enter drugs from...

Open access Research Article 10.9734/jpri/2023/v35i37315

Dentist ‘An Arsenal’ in the Journey of ‘Tooth in the Eye’-the Osteo-Odonto-Kerato-Prosthesis [OOKP]

Lakshmana Rao Bathala, U. S. B. Lakshmi, Dasari Jyothsna, Jagadeeswara Rao Sukhabhogi & Venkata Ramana Irukula · Journal of Pharmaceutical Research International · 2023

Background: Global blindness is mainly due to Cataract, after this Corneal disease is the major cause. For end stage corneal disease, the only successful treatment is by providing Osteo-Odonto-Kerato-Prosthesis (OOKP). The dental surgeon will play a vital role in this surgeon. Af...

Open access Research Article 10.9734/jpri/2023/v35i27312