Cisplatin (cis-diamine-dichloroplatinum (II), CDDP) is a prominent member of the effective broad-spectrum antitumor drugs. However, its clinical usage is restricted due to serious side effects particularly nephrotoxicity. The vulnerability of the kidney to CDDP is almost certainl...
Open access
Research Article10.9734/jpri/2021/v33i531178
With reference to Stoney scale, Wien’s displacement law and considering a light speed rotating black hole universe, in this letter, an attempt is made to estimate cosmic expansion rate, galactic dark matter, galactic flat rotation speeds and galactic radii. It can be appealed tha...
Background: Saliva is a versatile biofluid that can help in detecting any oral or systemic disease of an individual. Saliva seems to be clinically an informative biofluid for easy prognosis of a disease and clinical or laboratory diagnosis of oral as well as many systemic disease...
Open access
Research Article10.9734/jpri/2021/v33i431171
Aims: Nanoparticles are the colloidal carrier systems for delivery of poorly soluble drugs. Budesonide. (BUD) a corticosteroid practically insoluble in water is used in asthma treatment. The aim of the present research work was to develop and evaluate BUD nanoparticles. Methodolo...
Open access
Research Article10.9734/jpri/2021/v33i431172
Aim: To evaluate the impact of environmental pH on intra-radicular dentin push-out bond strengths of MTA, MTA HP, and Biodentine. Materials and Methodology: Freshly extracted human mandibular single-rooted premolars or maxillary anterior incisors that were either intact or contai...
Open access
Research Article10.9734/jpri/2021/v33i431173
Aim: Hypertension is a major public health problem worldwide and is associated with high mortality and morbidity. The main aim of this study is to assess obesity and overweight in school children and their relationship to hypertension and associated risk factors. Study Design: Po...
Open access
Research Article10.9734/jpri/2021/v33i431174
Objective: To determine the frequency of beta thalassemia trait among pregnant women presenting with anemia. Method: A cross sectional study was conducted in Gynecology & Obstetric department, district headquarters hospital Mardan from January 2019 to June 2020. This study in...
Open access
Research Article10.9734/jpri/2021/v33i531175
Aim: Cardiovascular disease (CVD) is a major health problem throughout the world and a common cause of premature morbidity and mortality. CVD is a general category of diseases that affects the heart and the circulatory system. The main aim of the study is to assess the prescribin...
Open access
Research Article10.9734/jpri/2021/v33i531176
Aim: To assess the drug-related problems (DRPs) and World Health Organization (WHO) core prescribing indicators among hospitalized diabetic patients. Methodology: A prospective, observational study was made among the diabetic inpatients of the General Medicine Department of a ter...
Open access
Research Article10.9734/jpri/2021/v33i531177
Aim: The present study was undertaken to describe the prescribing pattern of medications in the ophthalmology department in a public hospital in Alkharj. Methodology: This is a cross sectional study included collecting data from outpatient pharmacy prescriptions in a public hospi...
Open access
Research Article10.9734/jpri/2021/v33i431168
Aim: Iminothiazolidinones are one of the important classes of heterocyclic compounds and they occupied unique position in medicinal chemistry due to their wide range of biological and pharmaceutical properties. In view this potential activity, it has been planned to synthesize a...
Open access
Research Article10.9734/jpri/2021/v33i431169
Aim: Ramegepant is a novel molecule belongs to the class of calcitonin gene – related peptide (CGRP) receptor antagonist, which was developed for the prevention and treatment of migraine. Ramegepant was reported to act at the CGRP receptor with good oral bioavailability. The obje...
Open access
Research Article10.9734/jpri/2021/v33i431170
V. Sreedhar, L. Reddenna, T. Rajavardhana, J. Thippe Rudra, E. Pavan Kumar, M. Pramod Kumar, M. Kalyan Sai, T. Sivasaileela, Y. Yamini, B. Sreelekha, B. Nishkala & M. Mahesh·Journal of Pharmaceutical Research International·2021
There are diverse studies which afford evidences that risperidone is as effective as second generation antipsychotics in treating positive symptoms and more effective in treatment of negative symptoms. This study is intended to find the clinical efficacy and safety profile of lur...
Open access
Research Article10.9734/jpri/2021/v33i431167
The main objectives of this study were to qualitatively evaluate the profile of phytochemical constituents of Elytraria acaulis root (EAR) extracts. The dried powder of the roots of the plant was extracted with three different solvents namely petroleum ether, methanol and water,...
Open access
Research Article10.9734/jpri/2021/v33i431165
The major health problems affecting pregnant women in sub-Saharan African are anaemia, malaria and HIV. A case-control study aimed at determining the prevalence of malaria, anaemia and HIV status among women of reproductive age between 20-49 years attending General Hospital, Onit...
Open access
Research Article10.9734/jpri/2021/v33i431166