The objective of the present study was to investigate the antioxidant and hepatoprotective activity of ethanolic stem extract of Artabotrys zeylanicus against paracetamol (PCT), Ethanol (ETN) and Isoniazid and Rifampicin (IR) induced hepatotoxicity in Albino wister rats. Methodol...
Open access
Research Article10.9734/jpri/2020/v32i4731110
In young children, immunocompromised individuals, and elderly people, the respiratory syncytial virus (RSV) is the primary source of acute lower respiratory tract infection. Intervention with RSV-specific small-molecule antivirals may provide significant therapeutic potential. Fo...
Open access
Research Article10.9734/jpri/2020/v32i4731112
The “Type of Article” of this paper is “Letter to the Editor”. This paper discuses about: “Should Travellers have Priorities for COVID 19 Vaccine?”. No formal abstract is available. Readers are requested to read the full article.
Open access
Research Article10.9734/jpri/2020/v32i4731111
Azza Sarfraz, Zouina Sarfraz, Aminah Abdul Razzack, Donald Hathaway III, Sindhu Thevuthasan, Sarabjot Singh-Makkar, Trissa Paul, Gaurav Patel, Muhammad Khawar Sana, Muzna Sarfraz, Franz Richter & Marcos A. Sanchez Gonzalez·Journal of Pharmaceutical Research International·2021
Background: An unprecedented global effort in identifying potentially viable and emerging drugs for effective treatment of the novel coronavirus disease (2019) is being made. Of the most promising candidate therapies, convalescent plasma (CP), albeit controversial, is approved fo...
Open access
Research Article10.9734/jpri/2020/v32i4731113
The common neurodegenerative disorder of the central nervous system is multiple sclerosis (MS). It progresses with autoimmune inflammation and demyelination. Molecular basis study of MS pathogenesis is a significant element of field research, leading to new prevention and treatme...
Open access
Research Article10.9734/jpri/2020/v32i4631102
The Severe Acute Respiratory Syndrome (SARS) coronavirus-2 is a novel coronavirus belonging to the family Coronaviridae originating in Wuhan, China has created a impact across the globe. The disease has been declared a pandemic by the WHO on March 11, 2020. In this review, an up...
Open access
Research Article10.9734/jpri/2020/v32i4631104
The nitrogen heterocycle benzimidazoles have been known to be anthelmintic drugs. Beyond that role, the benzimidazoles exhibit other pharmacological potential as anti-inflammatory, antiulcer, anti-hypertensive and anticancer agents. A growing body of evidence supports the antican...
Open access
Research Article10.9734/jpri/2020/v32i4631105
With the growing era, there is tremendous need to produce high potential antimicrobial drugs and medicines from various herbaceous plants and natural resources has been increasing due to increasing multiple drug resistance in pathogens. An experiment was performed to know about a...
Open access
Research Article10.9734/jpri/2020/v32i4631103
Objective: To investigate whether CaMKⅡα participates in the dorsal root ganglion neurotoxicity induced by ropivacaine hydrochloride. Methods: DRG neurons were isolated from 1-day-old SD rats and cultured in vitro. pAd-shRNA-CaMKⅡα-DRG cells were constructed by RNA interference t...
Open access
Research Article10.9734/jpri/2020/v32i4731106
The increasing rate of drug-repellent pathogens and poisonousness of existing antiseptic compounds has strained attention toward activity of antimicrobial products which are natural. Main purpose of this research was to assess antimicrobial activity of seeds and leaves of Coriand...
Open access
Research Article10.9734/jpri/2020/v32i4731117
Aim: This study aimed to describe the prescribing pattern of methyldopa in a public hospital in Alkharj. Methodology: This is a retrospective study that was conducted to know the prescribing pattern of methyldopa. The data were collected from the outpatient electronic prescriptio...
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Research Article10.9734/jpri/2020/v32i4631101
Single Nucleotide polymorphisms are biological markers, helping researchers to locate genes that are associated with various diseases. When SNPs occur within a gene or in a regulatory region near a gene, they may play a more direct role in disease by affecting the gene's functi...
Open access
Research Article10.9734/jpri/2020/v32i4631099
Introduction: Improving communication and collaboration between members of the dental team is important to the long term aim of improving the quality of dental care for patients. The aim of this cross‑sectional study was to compare and assess the communication and interactions be...
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Research Article10.9734/jpri/2020/v32i4631098
Seventeen compounds from Syzygium aromaticum are selected for exo-β-(1,3)-glucanases inhibitory activity by using molecular docking study. The compounds are uploaded from the PubChem database and molecular docking with AutoDock 1.5.6 tools is carried out. The molecular docking sc...
Open access
Research Article10.9734/jpri/2020/v32i4631100
The aim of this study was to determine the microfungi and bacteria accumulated in different usage periods of paper mouth and face masks which are used for protection against microfungi and bacteria in many areas and to give antimicrobial properties to these masks by impregnating...
Open access
Research Article10.9734/jpri/2020/v32i4631096