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All published articles 7450

Antioxidant Drug Design: Historical and Recent Developments

Melford C. Egbujor, Samuel A. Egu, Vivian I. Okonkwo, Alifa D. Jacob, Pius I. Egwuatu & Ifeanyi S. Amasiatu · Journal of Pharmaceutical Research International · 2021

The sustained interest in the design of potent antioxidants drugs over the years can be attributed to the indispensable roles antioxidants play in the mitigation of oxidative stress and its concomitant diseases. The high demand for exogenous antioxidants has been ascribed to the...

Open access Research Article 10.9734/jpri/2020/v32i4131042

A Novel Antibacterial Topical Gel from Nigella sativa and Achyranthes aspera against Acne Causing Microorganisms

Iqra Rahat & Satish Kumar Sharma · Journal of Pharmaceutical Research International · 2021

Inflammation in sebaceous follicles leads to skin related maladies more specifically, acne vulgaris. Bacterial species involved in causing such maladies involve P. acnes, S. epidermidis, S. aureus. These microbes have negatively affected the currently available remedies for acne...

Open access Research Article 10.9734/jpri/2020/v32i4131043

Medicinal and Nutraceutical Benefits of Chia Seed (Salvia hispanica)

Loai F. Felemban, Atef M. Al- Attar & Isam M. Abu Zeid · Journal of Pharmaceutical Research International · 2021

Chia seeds (Salvia hispanica L.) are small seeds that develop on an annual herbaceous plant. Recently, there has been tremendous growth in the use of chia seeds because of their associated medicinal as well as high nutritional values. Initially, chia cultivation took place in Mes...

Open access Research Article 10.9734/jpri/2020/v32i4131040

Wound Healing Efficacy of Guava Leaf Extract

Sarah B. Delorino, Madeline L. Ogalesco, Kaye R. Rebadulla, Myrelle Tricia A. Rongcales, Joshua Ismael A. Salubre V, Maria Kristia S. Talacay & Zalde B. Tuballas · Journal of Pharmaceutical Research International · 2021

A wound is a break in the continuity of the skin. The body’s response to injury and the restoration of the same is healing. Wound healing is a biological process that is initiated by trauma and often terminated by scar formation. In this research, guava leaf extract was used as a...

Open access Research Article 10.9734/jpri/2020/v32i4131041

Epidemic Trend and Effect of COVID-19 Transmission in India during Lockdown Phase

Ranjit Prasad Swain & Pratap Kumar Sahu · Journal of Pharmaceutical Research International · 2021

To evaluate the present situation concerning the epidemic trend associated with the COVID-19 in Indian demography, the dynamics of the case rise has been analyzed from the perspective of the different index. The index for the analysis has been chosen in terms of the Case Recovery...

Open access Research Article 10.9734/jpri/2020/v32i3931027

Prescribing Patterns of Isosorbide Dinitrate in Outpatient Department of a Public Hospital

Nehad J. Ahmed & Menshawy A. Menshawy · Journal of Pharmaceutical Research International · 2021

Objective: The aim of this study was to describe the prescribing pattern of isosorbide dinitrate in outpatient department. Methods: The study was carried out at outpatient department in Alkharj. The collected data included personal data, dosage forms of the prescribed isosorbide...

Open access Research Article 10.9734/jpri/2020/v32i4031028

The Potential Therapeutic Advantage of Abrus precatorius Linn. an Alternative to Glycyrrhiza glabra: A Review

Ashaolu Victoria Oladimeji & M. F. Valan · Journal of Pharmaceutical Research International · 2021

Far back since the existence of the human race, plant species have been used as herb or medicine to either treat, suppress or cure the human numerous sicknesses. This poses the truth that green medicine is safe, cost-efficient, and effective with little or no side effects. Up-til...

Open access Research Article 10.9734/jpri/2020/v32i4031035

Effect of Short and Long Term Restraint Stress on the Histology of Liver, Kidney and Suprarenal Gland in Albino Mice during Postweaning Period

Othman Hakum Said, Chukwuma J. Okafor, Hassan Thabit Haji, Prakash B. Babu, Vanisri S. Nayak, Nkem F. Obianagha & Emilio Stivens Galano · Journal of Pharmaceutical Research International · 2021

On exposure to stress and for the sake of survival, cells make adjustments with the changes in their environment to the physiologic needs and non-lethal pathologic injury. When the environmental changes are greater than the capacity of the cell to maintain normal homeostasis the...

Open access Research Article 10.9734/jpri/2020/v32i4031029

Global Public Health Problem: Hypertension

Laxmidhar Moharana & Shakti Ketan Prusty · Journal of Pharmaceutical Research International · 2021

Hypertension is a big global public health problem. This research concentrates on exploring hypertension prevalence and its related causes in a Yemetu community located at Oyo States’ local in Nigeria. Hypertension is one of the most significant risk factor for cardiovascular dis...

Open access Research Article 10.9734/jpri/2020/v32i4031030

RP-HPLC Method Development and Validation for the Determination of Pemigatinib using Design of Experiments Approach

C. H. Srujani, K. Harika, K. S. Nataraj & A. Krishna Manjari Pawar · Journal of Pharmaceutical Research International · 2021

Aim: To develop and validate a simple, precise, accurate and robust RP-HPLC method for the determination of Pemigatinib by using Design of Experiments (DoE) approach. Study Design: A 23 Factorial design consisting of three factors at two levels was considered for the experimental...

Open access Research Article 10.9734/jpri/2020/v32i4031031

Evaluation as Disintegrant, Acetone-dehydrated Pre-Gelatinized Starch of Arthocarpus altilis Fruits in Oral paracetamol Tablets

T. O. Uwah, D. E. Effiong, E. I. Akpabio, G. Jacob & I. Awa · Journal of Pharmaceutical Research International · 2021

Introduction: Modifying natural polymers have imparted desirable properties making them suitable as pharmaceutical additives. Aim: This research work was to prepare pre-gelatinized breadfruit starch using acetone to reduce drying time and energy expended. The modified starch was...

Open access Research Article 10.9734/jpri/2020/v32i4031033

Controlled Release of Bi-Layered Malvidin Tablets Using 3D Printing Techniques

Tejinder Kaur & Suruchi Singh · Journal of Pharmaceutical Research International · 2021

Malvidin belongs to the class of anthocyanidin, a pigment compound present in fruits and vegetables like the colored berries, flowers, and vegetables which have pigments on it and it is available commercially as malvidin chloride. Malvidin is known to possess many medicinal chara...

Open access Research Article 10.9734/jpri/2020/v32i4031034

A Survey on the Prevalence of Anaemia in Pregnant and Lactating Women Eating Processed Food

Shakti Ketan Prusty & Pratap Kumar Sahu · Journal of Pharmaceutical Research International · 2021

Anaemia is a medical condition in which there is less number of red blood cells in the blood. Lack of sufficient healthy red blood cells in blood is observed in anaemia patients. In human beings, blood carries oxygen to other body tissues, transport of oxygen is done by red blood...

Open access Research Article 10.9734/jpri/2020/v32i4031036

Antidepressant Activity of Nardostachys jatamansi Extract in Animal Models of Depression

Faraz Saleem, Muhammad Owais Ismail, Zahida Memon & Faraz Arif · Journal of Pharmaceutical Research International · 2021

Background: Depression refers to a wide range of mental health problems characterized by the loss of interest in routine activities, low mood and a range of associated emotional, cognitive, physical and behavioral symptoms. It is one of the major causes of mortality as tendency o...

Open access Research Article 10.9734/jpri/2020/v32i4031037