The major objective of the current study is to implement a plan to enhance the dissolution rate and oral bioavailability of a poorly water-soluble aceclofenac. The drug is classified according to the biopharmaceutical classification system as class II drug. Amorphous alkalinized...
Open access
Research Article10.9734/jpri/2022/v34i647290
Drug abuse is a public health issue, particularly among adolescents and young adults. Therefore, the purpose of our study is to determine the prevalence rate of drugs use and to identify certain factors that can serve as predictors of drug use. A total of 431 students from Mohamm...
Open access
Research Article10.9734/jpri/2022/v34i647291
With increasing age, there is chance of developing different chronic conditions which are often accompanied by use of multiple medicines that can lead to polypharmacy which can be defined as use of five or more medicine which include the one that has been prescribed, over the cou...
Open access
Research Article10.9734/jpri/2022/v34i647293
Background: Worldwide, bacteremia is one of the serious infections that cause significant morbidity and mortality in hospitalized patients. A wide range of microorganisms have been implicated in the etiology of BSIs. Early detection of these pathogens along with the determination...
Open access
Research Article10.9734/jpri/2022/v34i647294
This paper studies the motion of an infinitesimal particle near the out-of-plane equilibrium points in the elliptic restricted three body problem (ER3BP) when the primaries are triaxial rigid bodies, sources of radiation with a Poynting-Robertson (P-R) drag force surrounded by a...
Aims: With the progress made in the treatment of cardiovascular patients, the use of anticoagulants such as warfarin, aspirin, ticlopidine, etc. have increased. This study aimed to investigate the frequency of use of warfarin-interfering drugs in warfarin toxicity patients admitt...
Open access
Research Article10.9734/jpri/2022/v34i627281
Objectives: The study explored the profiles of noncommunicable diseases (NCDs) of South Asian Bangladeshi immigrants aged > 55, access to health workshops about NCDs for self-care, and the types of support they needed to control and manage their NCDs. Methods: The study was...
Open access
Research Article10.9734/jpri/2022/v34i627282
Objective: A vital anti-oxidant, β-carotene has the capacity to reduce reactive oxidative stress, metabolic syndrome such as Type 2 (T2) Diabetes Mellitus (DM) and prevent inflammation, obesity, alzheimer and cardiovascular diseases in human. In this study, we evaluated the effic...
Open access
Research Article10.9734/jpri/2022/v34i627283
Aim: This study aimed to compare intraoperative and postoperative outcomes by using Conventional 2mm Miniplate versus 3-D plates in management of Mandibular Angle Fractures. Study Design: Randomized control trial. Place and Duration of Study: Department of Oral & Maxillofacia...
Open access
Research Article10.9734/jpri/2022/v34i637284
Einstein revisited his equations and altered by introducing something known as a universal constant. Einstein's 1917 concept has been with us ever since in various variants and incarnations, including the broader concept of 'Dark Energy’. Einstein’s field equation has been studyi...
Motivated by the tachocline region within the Sun, we investigate the interaction of buoyant structures with convection in a numerical set-up that resembles the base of the solar convection zone, where the fully compressible, non-linear magnetohydrodynamics equations are solved....
We virtually design here new subnanomolar range antimalarial, inhibitors of plasmodium falciparum M1 Aminopeptidase (PfA-M1), by means of structure-based molecular design. We developed the complexation QSAR models from Hydroxamic Acid derivatives (AHO). A linear correlation was e...
Open access
Research Article10.9734/jpri/2022/v34i607271
Amal B. Saeed, Rahaf A. Alshehri, Arwa W. Almaassri, Alaa M. Ahmed, Hadeel A. Nathar, Mada A. Barnawi, Jehan A. Zakzouk, Aman M. Alrohaibani & Sarah A. Almajaishi·Journal of Pharmaceutical Research International·2022
Aims: To summarize the currently available evidence to point out the different outcomes of static versus dynamic tests and to assess whether cyclic fatigue tests provide useful data and information for clinical practice. Study Design: Systematic review. Place and Duration of Study...
Open access
Research Article10.9734/jpri/2022/v34i607272
Introduction: Diabetes mellitus (DM) is a major chronic systemic health concern that could develop macro- and microvascular complications. One of the commonest microvascular complications is diabetic peripheral neuropathy (DPN) which is a type of nerve damage caused by uncontroll...
Open access
Research Article10.9734/jpri/2022/v34i607273
Ahmed Abdelsamie Fadl, Sultan Abdullah Hassan Alsuwaidani, Sukainah Mohammed Al Batti, Zahrah Hatim Saleh Al Saleh, Fatimah Abdullah AL Ghareeb, Zakiah Hussain Ali Alrebh, Louloah Abdullah Al Omran, Mohammad Salman ALRadhwan, Fatema Hussain Abdullah Almarhoon, Zahra Abdulkarim Saeed Almutlaq & Hussain Taher Al Aysh·Journal of Pharmaceutical Research International·2022
Psoriatic juvenile idiopathic arthritis is a subtype of juvenile idiopathic arthritis that is characterized by both arthritis and psoriasis. juvenile idiopathic arthritis (JIA) is a heterogeneous category of idiopathic inflammatory arthritis that affects children under the age of...
Open access
Research Article10.9734/jpri/2022/v34i617274