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The Content, Purification Degree, and Molecular Weight of Inulin of Natural Dangshen Roots (Codonopsis javanica) in Highland Lam Vien, Vietnam

Nguyen Thi Thang Long, Vu Ngoc Boi & Dang Xuan Cuong · Journal of Pharmaceutical Research International · 2020

Introduction: Inulins are a group of natural active polysaccharides found in ginseng and dangshen and mainly used in pharmaceutical preparations and functional food. The purification condition of inulin from dangshen grown in Vietnam did not occur in previous studies. Hence, the...

Open access Research Article 10.9734/jpri/2020/v32i2430813

Assessment of Antidiarrheal, Antispasmodic and Antimicrobial Activities of Methanolic Seeds Extract of Peganum harmala L. (Nitrariaceae)

Mohd Nazam Ansari · Journal of Pharmaceutical Research International · 2020

Background: Many plants and herbs have been shown to possess antidiarrheal, antispasmodic, and antimicrobial activities. The present study was developed to determine the possible antidiarrheal and antispasmodic effects of methanolic extract of Peganum harmala L. (MEPH) in diarrhe...

Open access Research Article 10.9734/jpri/2020/v32i2430812

The Motion of a Test Particle around the Out-of-Plane Libration Points in the ER3BP with Oblateness up to Zonal Harmonics J_4

Jagadish Singh & Tyokyaa K. Richard · Journal of Pharmaceutical Research International · 2020

The study of the Elliptic Restricted Three-Body Problem (ER3BP) in our present work  considered the  coordinates taken oblateness up to zonal harmonics  for Gliese 667 and Sirius systems. The   coordinates considered here is termed; the out-of-plane libration points. The out-of-p...

Open access Research Article

Assessing the Specificity of Paclitaxel towards the Marker Proteins of Breast Cancer Using In silico Molecular Docking Study

V. Senthil Kumar, T. V. Ajay Kumar & V. Parthasarathy · Journal of Pharmaceutical Research International · 2020

Breast cancer is highly prevalent next to lung cancer. Breast cancer occurs as a result of mutation in the genes like proto-oncogenes as well as tumor suppressor genes in a single clone of cells in the ductal and glandular regions of the breast. The drugs used to prevent breast c...

Open access Research Article 10.9734/jpri/2020/v32i2430811

Effects of Combination Therapy of Methotrexate with Leflunomide & Hydroxychloroquine: Comparative Clinical Trial

Qurrat-ul-Ain Bukhari, Kauser Ismail, Muzna Hameed Dar, Afshan Abbas & Madiha Ata · Journal of Pharmaceutical Research International · 2020

Aims: To study the role of combination therapies in the treatment of rheumatoid arthritis. Study Design:  This an open-label, randomized 180-days clinical trial. Place and Duration of Study: This study was conducted in the Department of Pharmacology and Therapeutics, BMSI and Med...

Open access Research Article 10.9734/jpri/2020/v32i2430810

Effect of Oral Administration of the Leaf Extract of Uvaria chamae (Mmimi Ohia) in Albino Wistar Rats

Innocent S. I. Ogbu, Eugenia O. Okafor, Emmanuel Ifeanyi Obeagu, Chinemerem C. Ogbu, Bessie Nonyelum. Esimai, Nduka J. Okeke & Chukwulete Okafor Ukeekwe · Journal of Pharmaceutical Research International · 2020

Uvariachamae (vernacular; mmimiohia) belongs to the family Annonaceae. It is a small tree that grows wild to about 4.5 meters in the savanna and rain forest regions of Nigeria and other African countries. It is known to possess various medicinal and therapeutic properties. The bi...

Open access Research Article 10.9734/jpri/2020/v32i2430809

Metabolic Changes in Newborns and Women Who Consumed Small Doses of Alcohol in the Prenatal Period

Anait Yuryevna Marianian, Natalya Vladimirovna Protopopova & Lyubov Ilinichna Kolesnikova · Journal of Pharmaceutical Research International · 2020

Introduction: Ethyl alcohol and its metabolites even in low concentrations negatively affectsan embryo and a fetus.Interest to the role of the lipid peroxidation-antioxidant defense (LPO-AOD) system has significantly increased in recent years, because this system imbalanceleads t...

Open access Research Article 10.9734/jpri/2020/v32i2430803

Cascade Variabilities in TB Case Finding among People Living with HIV and the Use of IPT: Assessment in Three Levels of Care in Cross River State, Nigeria

Michael Odo, Kingsley Chinedum Ochei, Emmanuel Ifeanyi Obeagu, Afirima Barinaadaa, Emmanuel Ugobo Eteng, Mabel Ikpeme, Jonah Offor Bassey & Andrew Ogar Paul · Journal of Pharmaceutical Research International · 2020

TB is the most common cause of morbidity and mortality in people living with HIV/AIDS (PLHIV) as it accelerates the progression of HIV infection. Every PLHIV is at an annual risk of 10% and a lifetime risk of 50% to acquiring TB and TB is responsible for the death of 30-40% PLHIV...

Open access Research Article 10.9734/jpri/2020/v32i2430789

The Significance of Tetrogenic Effect of Alcohol on the Fetus within the Educational Programs of Physicians and Its Practical Application

Anait Yuryevna Marianian, Natalya Vladimirovna Protopopova & Lyubov Ilinichna Kolesnikova · Journal of Pharmaceutical Research International · 2020

Background: The importance of the problem of drinking alcohol and further, negative consequences in the prenatal period and before planning the pregnancy is not understood sufficiently by the women as well as by the doctors. The goal of our research was to determine Russian speci...

Open access Research Article 10.9734/jpri/2020/v32i2430804

Knowledge and Source of Information of COVID-19 among Students of Health Informatics, Qassim University, Saudi Arabia

Sohail Akhtar, Ali H. Alharbi, Qazi Mohammad Sajid Jamal & Kesavan S. Nair · Journal of Pharmaceutical Research International · 2020

Background: The Kingdom of Saudi Arabia has undertaken strong measures to prevent the spread of COVID-19. Several steps were taken to communicate with the public on how the virus spreads and various precautionary measures to be taken to prevent the disease. The knowledge and perc...

Open access Research Article 10.9734/jpri/2020/v32i2430806

Optimization of Extraction of Polyphenolic Compounds from Medicinal Lungwort (Pulmonaria officinalis L.)

Lyubov S. Dyshlyuk, Anastasia M. Fedorova, Vyacheslav F. Dolganyuk & Alexander Yu. Prosekov · Journal of Pharmaceutical Research International · 2020

Medicinal plants are potential natural sources of biologically active substances that have geroprotective properties, slowing down the aging process. Vegetable raw materials are used as antioxidants in the food industry. Pulmonaria officinalis L. has a high content of biologicall...

Open access Research Article 10.9734/jpri/2020/v32i2430807

The Effect of Workload on Emotional Exhaustion and Its Impact on the Performance of Female Nurses at Hospital Dr. Tadjuddin Chalid Makassar

Syamsiar S. Russeng, . Wahiduddin, Lalu Muhammad Saleh, T. A. Tenri Diah & Harun Achmad · Journal of Pharmaceutical Research International · 2020

In hospitals, most nurses experience a decrease in performance due to the workload factor. Workload is a working condition and job descriptions that must be completed within a certain time. The too high workload experienced by nurses can result in emotional exhaustion, indirectly...

Open access Research Article 10.9734/jpri/2020/v32i2430808

Thyroid Dysfunction and Infertility of Women of Reproductive Age

Ekaterina Andreevna Sterlyova, Tatiana Kharitonovna Timokhina, Yuriy Viktorovich Sivkov, Alexandr Anatolyevich Markov, . Huldani, Vitaly V. Goncharov & Harun Achmad · Journal of Pharmaceutical Research International · 2020

Autoimmunity of the thyroid gland (TAI) or its dysfunction is quite common among women of reproductive age, and there are suggestions in the literature that they are associated with an unfavorable level of fertility and a negative outcome of pregnancy, as in the case of spontaneo...

Open access Research Article 10.9734/jpri/2020/v32i2330799

Teratogenic Effect of Chlorpyrifos and Glyphosate on Pregnant Rats: Biochemical and Morphological Evaluations

Jyoti Upadhyay, Mahendra Rana, Nidhi Tiwari & Mohd Nazam Ansari · Journal of Pharmaceutical Research International · 2020

The impact of pesticides on the environment and human health is a serious matter of concern. The present study focusses on the teratogenic effect of pesticide chlorpyrifos (CPF) and glyphosate (GLY) on the pregnant rats and their offspring during gestation and lactation period. T...

Open access Research Article 10.9734/jpri/2020/v32i2330800