Nerve injury caused by local anesthetics is a hot issue that people pay close attention to, and its mechanism has not been fully clarified. Type I interferon (I-IFN) is an important factor in regulating inflammatory response. In this study, SH-SY5Y cells were injured by ropivacai...
Open access
Research Article10.9734/jpri/2020/v32i2230766
A study to evaluate the levels of interferon-gamma, interleukins 6 and 10, hepcidin, iron status and some haematological parameters in persons living with human immunodeficiency virus was carried out. A total of 2000 subjects aged 18-60 years were enlisted for this study. The sub...
Open access
Research Article10.9734/jpri/2020/v32i2230767
Aims: This aimed to determine the prevalence of burnout syndrome and its associated factors among Saudi board residents in Saudi Arabia in 2019 Methods: The Cross-Sectional Study in all accredited training centers all over Saudi Arabia in 700 training centers accredited by SCFHS....
Open access
Research Article10.9734/jpri/2020/v32i2130764
The research was done to evaluate the levels of IFN-γ, IL-6, IL- 10, iron status, hepcidin and haematological parameters of patients with pulmonary tuberculosis and human immunodeficiency virus in a tertiary hospital, Southeast, Nigeria. Four hundred (400) subjects aged 18-60 yea...
Open access
Research Article10.9734/jpri/2020/v32i2130765
Bilawal Shaikh, Muhammad Ali Ghoto, Mudassar Iqbal Arain, Abdullah Dayo, Maryam Qazi, Arslan Ahmer, Rao Irfan, Tahseen Ahmed, Waqar Ahmed Sabzoi & Saleem Ahmed Joyo·Journal of Pharmaceutical Research International·2020
Pharmaceutical products of standard quality are very important in appropriate management of diseases. However, substandard drugs are failing to achieve the therapeutic outcomes. In this study, six brands of Captopril tables having two strengths (three brands of 50 mg, and three b...
Open access
Research Article10.9734/jpri/2020/v32i2130763
Antimicrobial or antibiotic resistance has become a leading cause of the death of millions of patients around the globe, including in the Kingdom of Saudi Arabia. Misuse of antibiotics has been identified as one of the main contributing factors to the emergence of antibiotic resi...
Open access
Research Article10.9734/jpri/2020/v32i2130762
Background: Lack of adherence to anti-diabetic medications use is linked with suboptimal glycemic control which in turn leads to increase rate of diabetic complications. The adherence to anti-diabetic medications among adult diabetic patients in Sana'a city has not been yet evalu...
Open access
Research Article10.9734/jpri/2020/v32i2130761
Background: Helicobacter pylori is a Gram-negative, winding, microaerophilic human pathogen and have indicated solid relationship with different gastroduodenal illnesses. Its contagion is one of the most widely recognized interminable diseases in humans since the isolation of the...
Open access
Research Article10.9734/jpri/2020/v32i2130759
Background: Stomach adenocarcinoma has been a major source of malignant development through the greater part of the 20th century. In different parts of the world, the prevalence of this disease has decreased, mostly due to changes in diet and some other natural constituents. Aim:...
Open access
Research Article10.9734/jpri/2020/v32i2130760
Aim: The objective of this study is to determine the phytochemical constituent and antibacterial effect of fruit extract of Datura metel against Staphylococcus aureus and Escherichia coli. Methods: The extract of the sample underwent a phytochemical screening to identify the seco...
Open access
Research Article10.9734/jpri/2020/v32i2130758
Citrullus vulgaris Schrad, commonly known as “watermelon” and Chrysophyllum albidum G., commonly called ‘‘Udara’’ are two important plants known to possess high antioxidant and therapeutic properties especially antidiabetic properties. The present study is aimed at investigating...
Open access
Research Article10.9734/jpri/2020/v32i2130755
Aim: The study of prescribing pattern is essential since it gives an idea to physicians about the process of monitoring and assessment of the drugs and endorses the required modifications. This study aimed to assess the outpatient prescribing pattern of ranitidine in a public hos...
Open access
Research Article10.9734/jpri/2020/v32i2130756
Objective: To assess the pharmacists’ perception and knowledge regarding the use of some chronic medication and appropriate administration timing. Methods: A cross-sectional survey was developed and randomly distributed to local retail pharmacies in the western region of Saudi Ar...
Open access
Research Article10.9734/jpri/2020/v32i2130757
In the context of the COVID-19 coronavirus pandemic, the risks of individual pharmaceutical market players or groups of players taking measures to supply medications that may lead to an economically unjustified increase in drug prices or artificially create a shortage of products...
Open access
Research Article10.9734/jpri/2020/v32i2130751
Background: A drug-drug interaction arises when the pharmacologic effect of a medication is changed by the action of other medication causing unexpected clinical effects. Drug-drug interactions are widely known but the identification of the consequences of food and drug interacti...
Open access
Research Article10.9734/jpri/2020/v32i2130752