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All published articles 7450

Screening of Enrofloxacin and Ciprofloxacin Residues in Chicken Meat by High-Performance Liquid Chromatography

M. K. Verma, A. H. Ahmad, Disha Pant, Parul Rawat, Sonam Sharma & Nidhi Arya · Journal of Pharmaceutical Research International · 2020

Enrofloxacin and Ciprofloxacin antibiotics are widely used in chicken production for prophylaxis and therapeutics purposes. Existence of these antibiotic residues in chicken meat can pose hazards to human health. The present study was aimed to assess the residue level of these an...

Open access Research Article 10.9734/jpri/2020/v32i2130753

Antioxidant and Hepatoprotective Potentials of Lasimorpha senegalensis Schott Leaf Extract on Carbon Tetrachloride-induced Liver Damage in Rats

Chinyere Blessing Chigor, Felix Ifeanyi Nwafor, Edith Ugwuja & Chisimdi S. Obi · Journal of Pharmaceutical Research International · 2020

Aims: The present study assessed the antioxidant and hepatoprotective potentials of the methanolic leaf extract of Lasimorpha senegalensis – a medicinal plant used by the indigenous people of Nigeria to treat hepatitis and feverish conditions. Place and Duration of Study: The res...

Open access Research Article 10.9734/jpri/2020/v32i2130754

Battle with COVID-19: Role of Vitamin D and Zinc as a Preventive Strategy

Pushpamala Ramaiah, Badria Abd Alla Mohamed Elfaki & Hassanat Elbashir Mohammed Mustafa · Journal of Pharmaceutical Research International · 2020

The immune system protects us by producing antibodies against viruses and diseases. Currently,  there is no cure in treating patients infected with COVID-19.  Even though many nations declared extrapolate findings on the COVID-19 vaccine trial, this will require months to develop...

Open access Research Article 10.9734/jpri/2020/v32i2130750

Virtual Screening to Identify the Protein Targets in Common Dental Pathogens Interacting with Menthol

J. S. Thaslima Nandhini, A. S. Smiline Girija & J. Vijayashree Priyadharsini · Journal of Pharmaceutical Research International · 2020

Deducing the molecular pathway underlying the antimicrobial effect of phytocompounds is an inevitable part of drug discovery. Selection of potential targets on the microbial pathogens will eventually lead to eradication of microbes and effective treatment. In this context, the pr...

Open access Research Article 10.9734/jpri/2020/v32i2130749

Synthesis and Characterization of Herbal Nano-suspensions and Evaluation of their In-vivo Antihypertensive Potential with Especial Focus on Piperine

Arifa Murtaza, Tayyba Rehman, Zohaib Zafar, Safia Noreen, Mahwish Iqbal, Samia Hassan, Iqra Khawaish & Muhammad Haseeb Anwar Tarar · Journal of Pharmaceutical Research International · 2020

Poor aqueous solubility is the principle obstacle in accomplishing suitable oral bioavailability for huge proportion of drug composites in drug development todays. Nano-suspension is an emerging field of research in the scientific community to provide a new solution for poorly wa...

Open access Research Article 10.9734/jpri/2020/v32i2030772

Biochemical Evaluation of the Effects of Quercetin On Experimental Acute Methanol Intoxication in Rats

Hasan Hüseyin Kozak, İbrahim Kılınç & Alpaslan Özkürkçüler · Journal of Pharmaceutical Research International · 2020

Previous studies have shown the role of oxidative stress in methanol toxicity. Also, studies have shown antioxidant, anti-inflammatory effects of quercetin (Q). This study evaluates the effect of quercetin (Q) administration on total oxidant status (TOS), total anti-oxidant status...

Open access Research Article 10.9734/jpri/2020/v32i2030743

Awareness on Lead Poisoning among College Students

M. V. Shreejha, V. Vishnu Priya & R. Gayathri · Journal of Pharmaceutical Research International · 2020

Lead is a highly toxic heavy metal. Chronic exposure to lead levels is responsible for significant health effects, particularly in children. Prevention remains the best option for reducing childhood lead exposure, however the knowledge, attitudes and practices to lead exposure is...

Open access Research Article 10.9734/jpri/2020/v32i2130744

Review on Clinical Diseases Caused by Klebsiella

K. Sathyavathy & B. Kiran Madhusudhan · Journal of Pharmaceutical Research International · 2020

Klebsiella are one among the group of gram negative rod shaped bacilli of family Enterobacteriaceae. Klebsiella are normal inhabitants of the intestinal tract of humans, animals, and environment. Klebsiella pneumoniae subspecies pneumoniae a most common gram negative lactose ferm...

Open access Research Article 10.9734/jpri/2020/v32i2130745

Frequency of Gall Bladder Carcinoma among Patients of Cholelithiasis at Tertiary Care Hospital

Mairaj Muhammad Khan, Agha Taj Mohammed, Rasool Bux Behan & Sohail Yousif · Journal of Pharmaceutical Research International · 2020

Objective: To determine the frequency of carcinoma of Gall Bladder in Hospitalized patients undergoing surgeries for cholelithiasis at tertiary care Hospital. Study Setting: General surgery department of Muhammad Medical College Mirpurkhas. Study Design: Descriptive.  Study Durat...

Open access Research Article 10.9734/jpri/2020/v32i2130746

Computational Approach to Identify Mutations in Genes of Notch Signaling Pathway and Its Association with OSCC

Madhumithaa Sivarajan, A. S. Smiline Girija, A. Paramasivam & J. Vijayashree Priyadharsini · Journal of Pharmaceutical Research International · 2020

Derailments in signal transduction pathways are associated with the development of tumors. One such vital pathway is the Notch signaling pathway which is associated with various processes of carcinogenesis such as proliferation of cells, cell renewal, angiogenesis and oncogenic m...

Open access Research Article 10.9734/jpri/2020/v32i2030732

Decoding the Genetic Alterations in PRAME Gene Family and Its Association with Head and Neck Squamous Cell Carcinoma

J. Dhivyadharshini, A. S. Smiline Girija, A. Paramasivam & J. Vijayashree Priyadharsini · Journal of Pharmaceutical Research International · 2020

Head and neck squamous cell carcinoma (HNSCC) is the most common form of cancer with an incidence rate greater in male than in female. Advancements in molecular diagnostics have identified several pathways which can have a direct or indirect role in the development and progressio...

Open access Research Article 10.9734/jpri/2020/v32i2030733

A Cross Sectional Survey of Knowledge, Attitude and Practice of Antibiotic Use for Children in Chennai among Mothers

B. Revathi & Kiran Kumar Pandurangan · Journal of Pharmaceutical Research International · 2020

Background and Aim: Mothers play a vital role in providing antibiotics to their children since they are too often affected with infections. Hence, the purpose of this study to assess the knowledge, attitude and practice towards antibiotic use of children in Chennai among mothers....

Open access Research Article 10.9734/jpri/2020/v32i2030734

Day to Day Use of Disinfectant Methods for Different Impression Materials among Dental Practitioners

Santhanam Panneer Selvam & V. Rakshagan · Journal of Pharmaceutical Research International · 2020

One of the major problems which most dental professionals face is cross contamination and cross infection. During the fabrication of dental prosthesis, special care should be taken for every step, especially impressions as they are one of  the main concern.  This  is because impr...

Open access Research Article 10.9734/jpri/2020/v32i2030735