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All published articles 7450

Preparation and Physicochemical Evaluation of Lumefantrine-2-Hydroxypropyl-β-cyclodextrin Binary Systems

Adebanjo J. Adegbola, Ezekiel Omotoso, Olujide O. Olubiyi, Julius O. Soyinkaa, Oluseye O. Bolaji & Cyprian O. Onyeji · Journal of Pharmaceutical Research International · 2020

Lumefantrine contributes significant roles in artemisinin-based combination therapy for malaria treatment but associated with a limitation of poor aqueous solubility and low permeability. This study investigated lumefantrine-2-hydroxypropyl-β-cyclodextrin complex to improve its s...

Open access Research Article 10.9734/jpri/2020/v32i1330589

Knowledge, Practices and Attitude of Healthcare Providers about Using Face Mask to Limit the Spread of the Novel Coronavirus Disease

Nehad J. Ahmed, Omar S. Alanazi, Abeer A. Alzahrani & Rana E. Alonazi · Journal of Pharmaceutical Research International · 2020

Aim: There is evidence that health care providers have insufficient knowledge and poor practices regarding the use of surgical mask. Therefore, this study aimed to explore the knowledge, practices and attitude of healthcare providers about using face mask in order to limit the sp...

Open access Research Article 10.9734/jpri/2020/v32i1330581

Evaluation of the P16INK4a Expression in Cervical Biopsy Specimen SBMCH

Amish Aggarwal, I. Venkatraman & M. Prabakaran · Journal of Pharmaceutical Research International · 2020

In early 1980 human papillomavirus (HPV) were the risk factor and most commonly affects younger women. Many test have developed since then and among that a biomarker test system have developed and clinically evaluated.  P16INK4a is used as an important marker for indicating neopl...

Open access Research Article 10.9734/jpri/2020/v32i1330582

Comparison between Conventional Gastric Adenocarcinoma and EBV Associated Gastric Carcinoma

A. R. Arshad, M. R. Rajashekar & N. Srinivasan · Journal of Pharmaceutical Research International · 2020

Epstein Barr Virus (EBV or Human herpesvirus 4) belongs to the genus Lymphocryptoviridae, the gamma 1 subtype of the Subfamily Gamma herpes viridae and is one of the most common viruses in humans. It is present in all populations, infecting more than 95% of all individuals within...

Open access Research Article 10.9734/jpri/2020/v32i1330583

Immunomodulatory Effects of Zinc as a Supportive Strategies for COVID-19

Nahla A. Tayyib, Pushpamala Ramaiah, Fatmah J. Alsolami & Mohammed S. Alshmemri · Journal of Pharmaceutical Research International · 2020

Coronaviruses 2019 (Covid-19) is a massive family of viruses that causes respiratory illnesses ranging from the common cold to the most severe conditions such as Middle East Respiratory Syndrome and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that represents the...

Open access Research Article 10.9734/jpri/2020/v32i1330577

Saudi Public Awareness Regarding Colon Cancer

Nehad Jaser Ahmed & Meshari Alrashidi · Journal of Pharmaceutical Research International · 2020

Background: Colorectal cancer is the third most common malignancy in the world and in Saudi Arabia it is the second most common cancer ranking first among men and third among women. In Saudi Arabia there are no screening programs on a national level that conduct organized screeni...

Open access Research Article 10.9734/jpri/2020/v32i1330578

Quality Control Measurement and in vitro Bioequivalence of Candesartan Cilexetil Tablets Marketed in Saudi Arabia

Mohammed Al- Bratty, Hassan A. Alhazmi, Hafiz A. Makeen, Asim Najmi, Md Shamsher Alam, Rabea Mussa Rabea Ageeli, Hisham M. A. Muzafar, Nawazish Alam & M. Intakhab Alam · Journal of Pharmaceutical Research International · 2020

Aim: Some generics were reported to be counterfeit and inferior quality than the innovators. This study was aimed to make sure about the compliance with standard specifications and evaluation of the quality of different selected brands (generic and innovator), after performing di...

Open access Research Article 10.9734/jpri/2020/v32i1230573

A Comparative Study on the Sexual Functioning among Men with and without Severe Mental Illness

P. Sudhan Raj, Lakshmi Prabha & S. Nambi · Journal of Pharmaceutical Research International · 2020

Objective: The aim of the study is to compare the sexual functioning among men with and without severe mental illness. Materials and Methods: The study was conducted in Psychiatry Department, Sree Balaji Medical College and hospital, Chromepet, Chennai Tamilnadu, India from the p...

Open access Research Article 10.9734/jpri/2020/v32i1230575

Analytical Pattern in Dermatoglyphics

S. R. Sruthy & Jayakar Thomas · Journal of Pharmaceutical Research International · 2020

Aim: The aim was to study the analytical pattern in dermatoglyphics. Materials and Methods: The study was conducted in Skin Opd, Sree Balaji Medical College and Hospital, Chennai, Tamil Nadu, India. A total of 100 participants with different hand dermatitis pattern were included...

Open access Research Article 10.9734/jpri/2020/v32i1330576

Generalization of Quantum Mechanical Wave Equation in Spherical Coordinate Using Great Metric Tensors and a Variable Gravitational Scalar Potential

A. U. Maisalatee, W. L. Lumbi, I. I. Ewa, M. Mohammed & Y. K. Kaika · Journal of Pharmaceutical Research International · 2020

In this research work, the Riemannian Laplacian operator for a spherical system which varies  with time, radial distance and time was obtained using the great metric tensors and a varying gravitational scalar potential. Furthermore the obtained Laplacian operator was used to obta...

Open access Research Article

Potential Anticancer Effects of Aged Garlic Extract and its Water-soluble Organosulfur Compounds

Huda Mohammed Alkreathy · Journal of Pharmaceutical Research International · 2020

Background: Cancer is among the leading causes of morbidity and mortality globally; it often leads to a steep rise in healthcare expenses. It is a known fact that various dietary ingredients such as aged garlic is an active anticancer agent, and its extracts do not have a strong...

Open access Research Article 10.9734/jpri/2020/v32i1230568

Evaluation of Free Radical Scavenging Potential of Different Bioactive Fractions Present in Boerhavia diffusa Linn. Root Extract: An in-vitro Approach

Mohammad Khalid, Mohammed H. Alqarni, Ahmed I. Foudah, Juber Akhtar, Badruddeen ., Ambreen Shoaib & Prawez Alam · Journal of Pharmaceutical Research International · 2020

Aim and Objectives: Boerhavia diffusa (B. diffusa) frequently known as punarnava is specifically used to replenish the body. The present work was designed to evaluate the scavenging potential of its bioactive constituents. Materials and Methods: The different fractions of B. diff...

Open access Research Article 10.9734/jpri/2020/v32i1230567

Phytochemical and Pharmacological Screening for Antidiabetic Activity of Salvia aegyptiaca L. Ethanolic Leaves Extract

Fazil Ahmad, Abeer Mohammed Al- Subaie, Rasheed Ahemad Shaik, J. Muthu Mohamed & Abdul Saleem Mohammad · Journal of Pharmaceutical Research International · 2020

Diabetes mellitus is a common metabolic disorder of carbohydrate, fat, and protein, which results in high levels of glucose in the body after a meal or fasting. This disease is caused by the absence or reduction of insulin secretion. Accordingly, diabetes is usually classified in...

Open access Research Article 10.9734/jpri/2020/v32i1230569