Autism is a neurodevelopmental illness marked by confined repetitive behaviour, poor social interaction, and difficulties with verbal and nonverbal communication. Despite advances in early detection and intervention, no therapy has yet been shown to entirely correct autism's basi...
Open access
Research Article10.9734/jpri/2022/v34i587260
Aims: The purpose of this study was to assess the knowledge, attitude and practice of healthcare workers about hand hygiene. Study Design: A cross sectional study was used. Place and Duration of Study: Memon Medical Institute Hospital, a tertiary care private hospital Karachi, P...
Open access
Research Article10.9734/jpri/2022/v34i587261
The concept of shear stress forms a fundamental base for meteorology and oceanography, which is the heritage of classical physics. In this paper, we show by well understood physical reasoning that it is also fundamental to cosmology although this link has not been previously rec...
The technique of lightening the shade of a person's teeth is known as tooth whitening or tooth bleaching. For a variety of reasons, teeth can become discoloured, and whitening is frequently the preferred solution. Nowadays aesthetics play a major role in today’s lifestyle. One of...
Open access
Research Article10.9734/jpri/2022/v34i577257
Parent-targeted oral health awareness campaigns should place a strong emphasis on issues like the value of deciduous teeth and how to treat them, frequent dental checkups, and dietary habits. The current study's objective is to evaluate parents' knowledge, behaviors, and attitude...
Open access
Research Article10.9734/jpri/2022/v34i577258
This study aims to determine chemical components and demonstrate the anti-inflammatory and analgesic activities of Vitex negundo species native to the Philippines. Using high-performance liquid chromatography (HPLC) and liquid chromatography-tandem mass spectrometry (LC-MS/MS), e...
Open access
Research Article10.9734/jpri/2022/v34i587259
Background: Shilajatu is one among the most used and important drugs in Ayurveda. However, a big percentage of Shilajatu samples available in market is not genuine. The analytical standards of Shilajatu are still not in Ayurvedic pharmacopoeia or any authoritative publication. So...
Open access
Research Article10.9734/jpri/2022/v34i577256
Introduction: The overall objective of the study was to evaluate the effect on blood glucose of the ethyl acetate-butanol fraction (EABF) compounds of the aqueous leaf extract of Dialium guineense (Cesalpiniaceae). Materials and Methods: The powder of D. guineense leaves was subj...
Open access
Research Article10.9734/jpri/2022/v34i567253
Background: Plasma kinins are known for decades but the understanding of them is not up-to the mark and the complexity is the reason. There are many drugs and trials undertaken with these as drug targets but only very few have been successfully marketed and used. Rest all others...
Open access
Research Article10.9734/jpri/2022/v34i577254
Aim: The main intention of the research work is to develop an effective, sensitive, economical and uncomplicated reverse phase HPLC technique for the estimation of Tofacitinib in Tofacitinib tablets dosage form. Study Design: HPLC based quantification studies. Place and Duration...
Open access
Research Article10.9734/jpri/2022/v34i577255
Introduction: Physical consequences have garnered the greatest attention during the coronavirus pandemic lockdowns, and few studies have studied the link between the COVID-19 lockdown and pre-existing mental health difficulties such as eating disorders (ED). Our main goal was to...
Open access
Research Article10.9734/jpri/2022/v34i567252
Dental caries is the chronic infectious disease caused by bacteria to from a biofilm formation on the tooth surface of man. Drug-resistant Streptococcus mutans (S. mutans) poses a vital public health issue. To overcome this, the development of effective drugs with novel mechanism...
Open access
Research Article10.9734/jpri/2022/v34i567249
Aims: Polyketide synthase 13 (Pks13) is an essential enzyme in the synthesis of mycolic acids biosynthesis pathway of Mycobacterium tuberculosis (Mtb). Therefore, Pks13 is a promising drug target for tuberculosis treatment. Here we report the in silico design and evaluation of no...
Open access
Research Article10.9734/jpri/2022/v34i567250
We virtually design here an important new weedkiller Cycloalka[d]quinazoline-2,4dione−Benzoxazinones (CQB), inhibitors of Protoporphyrinogen IX Oxidase (PPO). Based on computer-assisted combinatorial chemistry techniques, docking, 3D-QSAR and pharmacophore models we first enumera...
Open access
Research Article10.9734/jpri/2022/v34i567251
Background: Before and during the COVID-19 epidemic, the authors tried to measure the frequency of dental visits. They also tried to determine whether socioeconomic status, oral health diagnoses, and dental service providers can predict dental visits. Methods: Patients seeking de...
Open access
Research Article10.9734/jpri/2022/v34i557248