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All published articles 7450

Hydnora africana Derived Phytochemicals against Acetaldehyde Dehydrogenase of Aeromonas hydrophila Causing Septicemia

Debajani Tripathy, Chandana Adhikari, Mukundjee Pandey, Bhagyeswari Behera, Srimay Pradhan & Akshay Kumar Sahu · Journal of Pharmaceutical Research International · 2020

For drug discovery it takes approximately 6 years to expose in the market and for commercial uses. There are different procedure to get success in the drug discovery like preliminary phytochemical analysis, structural elucidation of the bioactive compound, preclinical test and cl...

Open access Research Article 10.9734/jpri/2020/v32i930539

Moringa oleifera Derived Phytochemicals against Shikimate Dehydrogenase of Helicobacter pylori Causing Peptic Ulcer

Sonali Suchismita Behera, Seema Suvadarshini, Truptimayee Chhotaray, Archita Sahoo, Subhadarshini Satapathy, Manasi Mohapatra, Bhagyeswari Behera & Srimay Pradhan · Journal of Pharmaceutical Research International · 2020

Moringa oleifera plant extract is traditionally used to cure Peptic ulcer. It is caused by Helicobacter pylori. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that 9-octadecenoi...

Open access Research Article 10.9734/jpri/2020/v32i930540

Moringa oleifera Derived Phytochemicals against 2-hydroxy-3-oxopropionate Reductase of Salmonella typhi Causing Typhoid

Sonali Suchismita Behera, Seema Suvadarshini, Ipsita Aparajita Mohapatra, Sonali Dash, Akshaya Kumar Sahoo, Soumyashree Nayak, Meenakshee Mohanty, Punya Prateek Majhi & Srimay Pradhan · Journal of Pharmaceutical Research International · 2020

Phytochemicals from Moringa oleifera plant extract can cure Typhoid. It is caused by Salmonella typhi. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that 4,8,12,16-tetramethylh...

Open access Research Article 10.9734/jpri/2020/v32i930534

Nigella sativa Derived Phytochemicals against Cough

Diptiprajnya Sahoo, Minati Nayak, Sidhartha Ray, Mukundjee Pandey, Kalpita Bhatta, Sushree Susmita Palei & Debasmita Rautaray · Journal of Pharmaceutical Research International · 2020

Nigella sativa plant extract is traditionally used to cure cough. It is caused by Bordetella pertussis. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that p-cymene can effectiv...

Open access Research Article 10.9734/jpri/2020/v32i930535

Alkanna tinctoria Derived Phytochemicals against Staphylococcus aureus Causing Eczema

Utapa Nayak, Elora Barik, Bijan Kumar Patra, Smruti Ranjan Behera, Mukundjee Pandey, Kalpita Bhatta, Arsia Tabish & Prabhashini Behera · Journal of Pharmaceutical Research International · 2020

Alkanna tinctoria plant extract is traditionally used to heal eczema. It is caused by Staphylococcus aureus. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that 2-Hydroxy-3-Phen...

Open access Research Article 10.9734/jpri/2020/v32i930536

Antioxidant Nano Phlorotannin Powder from Brown Algae Sargassum serratum: Spray Drying, Antioxidant Activities, Physic-Chemical Characterization

Dang Xuan Cuong · Journal of Pharmaceutical Research International · 2020

Introduction: Phlorotannins are bioactive-value polymers existing in brown algae and useful for pharmaceutics and functional food. Therefore, the study focused on the spray drying conditions survey, the evaluation of antioxidant activities, and physico-chemical characterization o...

Open access Research Article 10.9734/jpri/2020/v32i930484

A Review of Recent Phytomedicinal Investigations and the Need for DNA Barcoding of Endemic Plants of Northern Cyprus

Dudu Özkum Yavuz & Mustapha Bulama- Modu · Journal of Pharmaceutical Research International · 2020

Aims: To review the phytomedicinal researches on endemic plants of Northern Cyprus and to assess the plants of their DNA barcoding status. Study Design: A review. Methodology: This work reviewed available and accessible original articles in EBSCO, Ovid MEDLINE®, PubMed®, ScienceD...

Open access Research Article 10.9734/jpri/2020/v32i930483

Chloroquine and Hydroxychloroquine could be an Available Weapons to Treat COVID-19 Associated Pneumonia

Nehad J. Ahmed · Journal of Pharmaceutical Research International · 2020

Aims: This study aims to review the efficacy of chloroquine and hydroxychloroquine to treat coronavirus disease 2019 (COVID-19) associated pneumonia. Methodology: This review includes searching Google scholar for publications about the use of hydroxychloroquinein the treatment of...

Open access Research Article 10.9734/jpri/2020/v32i930482

Sleeping Duration, Bedtime and BMI and Their Rapport on Academic Performance among Adolescents

Walid Abu Rayyan, Shadi Salem, Wael Abu Dayyih, Aseel Al Shawareb, Riad Awad, Yazan S. Batarseh & Hisham Y. Al Matubsi · Journal of Pharmaceutical Research International · 2020

Background: Proper development of cognitive skills during childhood is substantially connected with adequate sleeping. Sleeping is drastically undergoing pattern changes during the shifting from childhood to adolescence. The academic acquisition is a multifactorial process with d...

Open access Research Article 10.9734/jpri/2020/v32i930477

Examination of Bacterial Pathogens an in Intensive Care Unit of a Military Hospital in Alkharj

Nehad J. Ahmed · Journal of Pharmaceutical Research International · 2020

Aim: The present study was undertaken to identify the most common infectious agents for Intensive Care Unit (ICU) patients in a military hospital in Alkharj – Saudi Arabia. Methodology: This study was conducted in a military hospital in Alkharj – Saudi Arabia. Identification of G...

Open access Research Article 10.9734/jpri/2020/v32i930478

Assessment of the Knowledge and Self-medication Practices towards Antibiotics among Future Healthcare Professionals in Ajman, United Arab Emirates

Mariam Aboulilah, Sara Ahmed, Razan Jarjouma, Razan Sabri & Subish Palaian · Journal of Pharmaceutical Research International · 2020

Objectives: The aim of the study is to assess the knowledge and self-medication behavior among health professions students regarding antibiotic usage. Methods: A cross-sectional study was performed using a self-administrated questionnaire. A sample of 424 questionnaires was distr...

Open access Research Article 10.9734/jpri/2020/v32i930479

Prevalence of Bacterial Pathogens Isolated in 2018 from Patients in a Military Hospital

Nehad J. Ahmed · Journal of Pharmaceutical Research International · 2020

Aim: The aim of the present study was to describe the prevalence of bacterial pathogens isolated from patients in a military hospital in Alkharj. Methodology: This was a retrospective study conducted to describe the prevalence of bacterial pathogens in 2018. Clinical culture resu...

Open access Research Article 10.9734/jpri/2020/v32i930480

Influence of Angiotensin Receptor Blocker (Candesartan) and Angiotensin-Converting-Enzyme Inhibitor (Enalapril) Combined with Glimepiride on Glycated Hemoglobin in Non-Insulin Dependent Diabetic Rats (NIDDM)

Abdulwahab Al-Badri, Eyad Mallah, Zainab Zakarya, Ramadan Al-Shdefat, Feras Darwish El-Hajji, Mo’ath Ifraitekh, Abeer Kharshid & Wael Abu Dayyih · Journal of Pharmaceutical Research International · 2020

Background: Antihypertensive agents like Angiotensin-Converting Enzyme Inhibitors (ACEIs) and Angiotensin-Converting Enzyme Blockers (ARBs) are commonly indicated for patients with both hypertension and diabetes. However, the effect of these agents on blood sugar level or glycate...

Open access Research Article 10.9734/jpri/2020/v32i930481

Anti-inflammatory Potentials of Fibraurea tinctoria Leaves Extract in Experimental Rats or Animals

Fahad I. Al-Saikhan · Journal of Pharmaceutical Research International · 2020

The activity of the hydroalcoholic extract of Fibraurea tinctoria leaves and anti-inflammatory was investigated. We utilized rats for which oedema was induced by carrageenan.  The extract of Fibraurea tinctoria leaves was administered orally at doses of 100, 200 and 400 mg/kg. Pa...

Open access Research Article 10.9734/jpri/2020/v32i830474