Skip to content

All published articles 7450

Design, Synthesis, Antimicrobial and Antioxidant Activities of Novel Threonine-based Sulfonamide Derivatives

M. C. Egbujor, U. C. Okoro, D. C. Nwobodo, C. U. Ezeagu, U. B. Amadi, C. G. Okenwa-Ani, J. I. Ugwu, I. G. Okoye, I. P. Abu & P. I. Egwuatu · Journal of Pharmaceutical Research International · 2020

Aim: To systematically design, synthesize and evaluate the biological activities of new threonine-based sulfonamide derivatives in order to achieve improved drug potency. Methodology: Sulfamoyl carboxylic acids were prepared by the reaction of threonine with the appropriate sulfo...

Open access Research Article 10.9734/jpri/2020/v32i830470

Optimizing the Use of Hydroxychloroquine in the Management of COVID-19 Given Its Pharmacological Profile

Ahmed S. Ali, Mahran S. Abdel-Rahman, Riyadh S. Almalikil, Abir S. Mohamed, Khalid A. Alfaifi, Abdelbabgi El. Fadil, Nagla A. El-Shitany & Huda M. Alkreathy · Journal of Pharmaceutical Research International · 2020

After the global pandemic of the new coronavirus, its rapid spread and many victims, it is necessary to find an effective vaccine or drugs to overcome it. Most specialists consider that repositioning some medications is the best, fastest and most reliable option for treating pati...

Open access Research Article 10.9734/jpri/2020/v32i830468

Evaluation of Drug-related Knowledge and Clinical Skills among Future Healthcare Professionals

Muhammad Shahid Iqbal, Muhammad Zahid Iqbal, Sawri Rajan & Nehad J. Ahmed · Journal of Pharmaceutical Research International · 2020

Background: The main objective of this study was to determine and compare current drug-related knowledge and clinical skills in terms of medication error identification among future healthcare professionals. Methods: Study participants were asked to identify errors in three diffe...

Open access Research Article 10.9734/jpri/2020/v32i830469

Coffea arabica L. Derived Phytochemicals against Haemophilus influenza Causing Conjunctivitis

Sutapa Nayak, Elora Barik, Biren Pattanayak, Sitaram Swain & Dipankar Bhattacharyay · Journal of Pharmaceutical Research International · 2020

Phytochemicals from Coffea arabica plant extract are traditionally used to cure conjunctivitis. It is caused by Haemophilus influenza. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” sugge...

Open access Research Article 10.9734/jpri/2020/v32i730517

Eclipta alba L. Derived Phytochemicals against Campylobacter Causing Diarrhea

Sanchayita Nayak, Subhashree Sahu, Mukesh Kumar Biswal, Sonali Dash, Sagarika Parida & Sabita Pattanayak · Journal of Pharmaceutical Research International · 2020

Phytochemicals from Eclipta alba L. plant extract are traditionally used to cure Diarrhea. It is caused by Campylobacter. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDocker energy and -CDocker interaction energy” suggested that 6,...

Open access Research Article 10.9734/jpri/2020/v32i730518

Eclipta alba L. Derived Phytochemicals against Escherichia coli Causing Diarrhea

Krishna Rani, Aischarya Mohanty, Sagarika Parida, Manisha Mohanty, Subhashree Sahu, Sanchayita Nayak & Sutapa Mohanty · Journal of Pharmaceutical Research International · 2020

Phytochemicals from Eclipta alba L. plant extract are traditionally used to cure Diarrhea. It is caused by Escherichia coli. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that...

Open access Research Article 10.9734/jpri/2020/v32i730519

Eclipta alba Derived Phytochemicals against Jaundice

Sutapa Mohanty, Mukesh Kumar Biswal, Sanchayita Nayak, Bhagyeswari Behera, Ushasree Mandal & Srimay Pradhan · Journal of Pharmaceutical Research International · 2020

Phytochemicals otherwise known as secondary metabolites means the small organic molecules that are not essential for growth, development and reproduction but can protect from various diseases. Infact these phytochemicals are the key source of medicine. Secondary metabolites from...

Open access Research Article 10.9734/jpri/2020/v32i730520

Budleja asiatica Derived Phytochemicals against Eye Disease

Sarthak Siddhant Mishra, Sasmita Patra, Bhakti Bhusan Das, Dipankar Bhattacharyay & Mukundjee Pandey · Journal of Pharmaceutical Research International · 2020

The secondary metabolites in the plants are the reason for curing various diseases. And the phytochemicals present in Budleja asiatica plant extract can cure Eye disease which is caused by Haemophilus influenzae is a facultatively anaerobic, gram-negative pathogenic bacteria. For...

Open access Research Article 10.9734/jpri/2020/v32i730521

Guava Seeds Derived Phytochemicals against Dysentery

Lopita Mishra, Barsha Nayak, Bibhu Prasad Mishra, Dipankar Bhattacharya & Mukundjee Pandey · Journal of Pharmaceutical Research International · 2020

Phytochemicals are the secondary metabolites that are known as nonnutritive but extremely beneficial for the defensive system for the organism. These phytochemicals can be obtained from all the plants and they play a major role in curing differnt diseases. The extract of the guav...

Open access Research Article 10.9734/jpri/2020/v32i730522

Incidence of Candida Species Infections in a Military Hospital in Al-Kharj, Saudi Arabia

Nehad J. Ahmed · Journal of Pharmaceutical Research International · 2020

Aim: The present study aims to demonstrate the incidence of Candida species associated with infections in a Military hospital in Alkharj. Methodology: This is a retrospective study that was conducted to assess the prevalence of Candida species in a Military hospital in Alkharj –...

Open access Research Article 10.9734/jpri/2020/v32i830465

Effect of a Period of Magnesium Supplementation on Muscle Strength and Resistance of Bodybuilders

Seyyed Mehdi Razavi Dehkordi · Journal of Pharmaceutical Research International · 2020

Objective: The purpose of this study is to determine the effect of magnesium supplements on the muscular strength of active men. Materials and Methods: Samples were matched into two groups. Magnesium supplements (containing 47 mg of calcium and 250 mg of magnesium oxide produced...

Open access Research Article 10.9734/jpri/2020/v32i830466

The Adverse Effect Reporting for the Most Commonly Used Antibiotics

Nehad J. Ahmed, Mohammed I. Fouda, Dina I. Fouda & Ahmed I. Foudah · Journal of Pharmaceutical Research International · 2020

Aim: Antibiotics save lives, but the excess use of antibiotics leads to more side effects. Patients benefit from medications but also complain about their adverse effects. This study aims to explore the reports of the adverse effects for the most commonly used antibiotics in Saud...

Open access Research Article 10.9734/jpri/2020/v32i830467

Trigonella foenum-graecum Derived Phytochemicals against Cellulitis

Bidyashree Tripathy, Soumya Jal & Dipankar Bhattacharyay · Journal of Pharmaceutical Research International · 2020

Cellulitis is a common and sometimes painful bacterial skin infection. Trigonella foenum-graecum extract is traditionally used to cure diseases like cellulitis. Phytochemicals from Trigonella foenum-graecum plant extract can cure Cellulitis. The objective of the study is to ident...

Open access Research Article 10.9734/jpri/2020/v32i730514