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Chromatographic Behaviour of Antibiotics on Thin Layers of Zeolite

Adham Raeisi, Mostafa Ramezani, Hossein Ravazadeh & Mahdi A. Taher · Journal of Pharmaceutical Research International · 2019

Introduction: Antibiotics analysis is performed by many methods such as spectrophotometry, fluorimetry, polarography, and high-performance liquid chromatography. This analysis doesn't require derivatization but requires expensive equipment and extensive preparation. When more tha...

Open access Research Article 10.9734/jpri/2019/v30i430273

Hepatoprotective Effects of Suberoylanilide Hydroxamic Acid (A Histone Deacetylase Inhibitor) in Immunological Liver Injury in Rats

A. Alhaddad, H. Abdel Kawy, W. Ramadan & A. Abbas · Journal of Pharmaceutical Research International · 2019

One of the main reasons for the development of chronic liver disease is autoimmune hepatitis (AIH).  There is no clear etiological factor for AIH occurrence and no drug has been approved for its treatment. Vorinostat, a Histone deacetylase inhibitor (HDACi) has been shown to redu...

Open access Research Article 10.9734/jpri/2019/v30i330271

Provision of Sexual and Reproductive Health Services in Community Pharmacies: A Cross-Sectional Assessment of Structures and Processes in Jos, Nigeria

M. P. Dapar, B. N. Joseph, A. P. Damun, R. C. Okunlola, H. A. Ibrahim, S. G. Mohammed, M. P. Chingle & N. N. Wannang · Journal of Pharmaceutical Research International · 2019

Background: Community pharmacies are located close to the people, open long hours and weekends, making them ideal for provision of sexual and reproductive health (SRH) services, as a means of enhancing access and achieving universal coverage. However, structures (encompassing fac...

Open access Research Article 10.9734/jpri/2019/v30i330272

In vitro Activity of Ceftolozane/Tazobactam for the Treatment of Complicated Urinary Tract Infections by Escherichia coli in the Era of Antibiotic Resistance “Rejuvenate the mystery”

Lubna Farooq, Shaikh Nadeem Ahmed, Muhammad Aitmaud Uddolah Khan, Akhtar Ali, Sehrish Mehmood & Humaira Arif · Journal of Pharmaceutical Research International · 2019

Background: Urinary tract infections are found to be commonest bacterial infections across the globe. Various studies have demonstrated high prevalence rate of UTIs in Pakistan. Multiple broad spectrum antibiotics are being used for the treatment of UTI but the resistance by the...

Open access Research Article 10.9734/jpri/2019/v30i330270

The Effect of Intervention with Acupressure Therapy on Improving Overall Male Sexual Performance

Roohallah Bay, Khodabakhsh Ahmadi, Ali Fathi-Ashtiani & Mohammad Hossein Zarghami · Journal of Pharmaceutical Research International · 2019

Background and Objective: The purpose of this study was to evaluate the efficacy of acupressure therapy on improving the overall male sexual performance.  Acupressure therapy is a therapeutic approach that assumes that throughout the body there are certain nerves that have a dire...

Open access Research Article 10.9734/jpri/2019/v30i330268

Drosophila melanogaster: A Veritable Genetic Tool and in vivo Model for Human Alzheimer’s Disease

Oluwatosin Imoleayo, Oyeniran · Journal of Pharmaceutical Research International · 2019

The rise in the cases of neurodegenerative diseases, such as the familial forms of Alzheimer’s disease is worrisome and a burden to many societies in our ever-increasing world. Due to the complexity in the nature of the brain and spinal cord characterized by an extremely organize...

Open access Research Article 10.9734/jpri/2019/v30i230264

The Antiangiogenic Effects of Tamoxifen might be Attributed to Receptor Binding Capacity of its Solvent Dimethylsulfoxide in Breast Cancer: A Molecular Docking Study

Orhan Koçak, Nazlı Deniz Taşkın & Ece Şimşek · Journal of Pharmaceutical Research International · 2019

Aim: Tamoxifen, a Dimethyl sulfoxide (DMSO)-soluble chemotherapeutic, is widely used in the treatment of breast cancer. Tamoxifen has an anti-angiogenic effect especially on breast tumor cells by blocking VEGF(Vascular Endothelial Growth Factor) production. On the other hand, acc...

Open access Research Article 10.9734/jpri/2019/v30i230265

A Review on Novel Progressions in Intravenous (IV) agents for Anesthesia

Babak Hosseinzadeh Zoroufchi & Abolfazl Abdollahpour · Journal of Pharmaceutical Research International · 2019

One of the main medical proficiencies involved with the procedure of patient’s perioperative care before, during and after operation is anesthesiology. This field of science has made a lot of hopeful progression in detection of new, secure, impressive, and productive procedures f...

Open access Research Article 10.9734/jpri/2019/v30i230266

Determination of the Effect of High-Dose Intralipid in Compared to Its Gradual Dose in Very Low Birth Weight Newborns: A Case-control Study

Mandana Kashaki, Arash Bordbar, Ali Mazouri, Nikta Nikbakht & Babak Jafarvand · Journal of Pharmaceutical Research International · 2019

Objective: The aim of this study was to determine the effect of high dose intralipid in compared to its gradual dose in very low birth weight newborns in Iran.  Methods: This study was a case-control study that conducted on 104 very low birth weight infants (<1500 g) referred...

Open access Research Article 10.9734/jpri/2019/v30i230267

Effect of Cyclophosphamide and Its Combination with Metformin on the Survival Rate in Mice

Ahmad Alhowail, Sultan Sajid, Yasser Almogbel, S. I. Rabbani & Mansour Alsharidah · Journal of Pharmaceutical Research International · 2019

Background: Cyclophosphamide (CYP), an alkylating chemotherapeutic agent, is widely used to treat several types of cancer. Its toxic effects are well-established and include hepatotoxicity, nephrotoxicity, and bone marrow suppression. Metformin (MET) is an anti-diabetic medicatio...

Open access Research Article 10.9734/jpri/2019/v30i230263

Formulation, in vitro and Bioavailability Assessments of Ranitidine Rectal Suppositories

Khaled Shalaby, Ahmed M. Samy, Alaa Kassem, Mohamed F. Ibrahim, Nabil K. Alruwaili, Hazim M. Ali & Mohammed Elmowafy · Journal of Pharmaceutical Research International · 2019

The objective of the current work was to develop and evaluate suppository dosage form in order to improve ranitidine bioavailability as a substitute to the oral administration. Suppocire (different grades), Witepsol W25 and polyethylene glycol (PEG) were used as suppository bases...

Open access Research Article 10.9734/jpri/2019/v30i130262

Inhibitory Effect of Dry Garlic Powder on the Nickel Chloride-induced Somatic and Germinal Cell Damages in Male Mice

Syed Imam Rabbani · Journal of Pharmaceutical Research International · 2019

Background: Nickel is commonly used in industry, utensils and also present in cigarette. Over-exposure of nickel is known to cause several health complications including somatic and germinal cell injuries. Garlic (Allium sativum) being a spice has several pharmacological properti...

Open access Research Article 10.9734/jpri/2019/v30i130261

Jeans Instability of Fine Dust Particle with Impact of Coriolis Force, Electrical Resistivity and Electron Plasma Frequency

D. L. Sutar, S. Sharma & R. K. Pensia · Journal of Pharmaceutical Research International · 2019

The present paper deals with the theoretical investigation of the combined influence of Coriolis force, electrical resistivity, electron plasma frequency and fine dust particles on the linear Jeans instability of gaseous plasma by using the generalized magneto-hydrodynamic fluid...

Open access Research Article 10.9734/iaarj/2019/v1i13

The Effectiveness of Acceptance and Commitment Therapy on the Illness Perception in Dialysis Patients

Shiler Karimi, Fardin Moradimanesh, Parviz Asgari & Saieed Bakhtiyarpour · Journal of Pharmaceutical Research International · 2019

One of the proposed psychological treatments in hemodialysis patients is acceptance and commitment therapy. The acceptance and commitment therapy focuses on psychological flexibility and this occurs when a person consciously accepts his or her thoughts and feelings and shows a be...

Open access Research Article 10.9734/jpri/2019/v30i130260