Background: COVID-19 Pandemic had led to an unprecedented emergency which led to many transformations in all aspects of life including dietary practices. A good and balanced die played a crucial role in prevention of disease and faster recovery. For a good dietary practice, knowl...
Open access
Research Article10.9734/jpri/2022/v34i54A7234
Background: Gene therapy has proved to be a boon for neuromuscular diseases. A concept introduced in the early 1960’s, has been put into clinical practice in the past 5-10 years. The process by which a healthy gene replaces a defective gene in a human body through vectors is trul...
Open access
Research Article10.9734/jpri/2022/v34i53B7229
Diabetic foot ulcers (DFU) are chronic wounds, which do not respond to traditional wound treatments. In this work, wound dressings of glibenclamide (GB) incorporated into a novel mixed matrix were fabricated in the aim of accelerating the healing process of diabetic wounds. GB w...
Open access
Research Article10.9734/jpri/2022/v34i53B7230
Artificial Intelligence has exploded as a research subject in the 21st century as the hardware requirements of theoretical Artificial intelligence in the 19th and 20th century have translated into reality. This has led to rapid progress with the realization of multiple kinds of n...
Open access
Research Article10.9734/jpri/2022/v34i53B7228
Pharmaceutical agents which treat rare medical conditions like orphan or rare diseases are called “orphan drugs”. The name ‘orphan’ itself indicates that the pharmaceutical industries are showing less interest in the development and marketing of drugs intended only for a small nu...
Open access
Research Article10.9734/jpri/2022/v34i53B7227
Aims: To determine the toxicity of astemizole-methylene blue combination therapy as effective candidates for therapeutic repurposing against malaria. Study Design: Randomized block study design. Place and Duration of Study: Department of Tropical and Infectious Diseases, Institut...
Open access
Research Article10.9734/jpri/2022/v34i53A7226
Background: Skin lightening creams & products (SL) contain certain dangerous chemicals such as mercury, steroids such as; Clobetasol propionate (CP), hydroquinone (HQ), and a host of others that have negative health implications. Aims: The study focused on the knowledge, atti...
Open access
Research Article10.9734/jpri/2022/v34i53A7225
The Covid-19 virus (CoV) has worsened due to its transmissibility worldwide. Several millions of people have been infected since 2019 when it was first detected. Unpredictable impact and disruption created by the pandemic influence global financial or economic crisis. This motiva...
Open access
Research Article10.9734/jpri/2022/v34i53A7224
Keloids are benign tumors that grow as a result of excessive collagen release from overexpressed fibroblasts. Keloids and hypertrophic scars are distinguished by the fact that keloids develop beyond the site of the original lesion, but hypertrophic scars do not. It is still uncle...
Open access
Research Article10.9734/jpri/2022/v34i53A7222
Objectives: The objective of the present work is to develop and validate a HPLC method with PDA detector to determine Pantoprazole and Itopride in bulk and tablet formulation. Methods: This Chromatographic method uses Phenomenex Luna C18 (4.6 mm × 250 mm) having particle size (...
Open access
Research Article10.9734/jpri/2022/v34i53A7223
Background: Lack of knowledge and awareness of the society is one of the major contributing factors to the prevalence of counterfeit medicines in a country. There is limited information in the developing countries on university student’s facts concerning counterfeit medicines. Ai...
Open access
Research Article10.9734/jpri/2022/v34i52B7220
Introduction: Carbapenems are found in high concentrations in urine and are mainly eliminated by the kidney. Hence, they are the preferred treatment for pyelonephritis and complicated urinary tract infections (cUTIs) caused by extended-spectrum β-lactamase (ESBL) producing bacter...
Open access
Research Article10.9734/jpri/2022/v34i52B7219
Aim: The main purpose of the research is to develop a effective, sensitive, economical and simple reverse phase HPLC method for the determination of genotoxic N-Nitrosamine's impurities in Efavirenz drug substance. Study Design: HPLC based quantification studies Place and Durati...
Open access
Research Article10.9734/jpri/2022/v34i52B7218
Aims: New validated method for the simultaneous estimation of Bupropion and Dextromethorphan using HPLC. Place and Duration of Study: Department of Chemistry, RVR & JC College of Engineering, Chowdavaram, Guntur, Andhra Pradesh, between July 2022 and August 2022. Methodology:...
Open access
Research Article10.9734/jpri/2022/v34i52B7217
Aim: This study aimed at formulating and optimizing the multiparticulate system of Rifaximin by adopting 32 factorial designs with independent variables X1 and X2 as concentrations of two excipients. Methodology: The pellets were prepared by the Extrusion Spheronization method an...
Open access
Research Article10.9734/jpri/2022/v34i52B7216