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All published articles 7450

Study of Interaction between Tigecycline and Sulbactam

Hakan Sezgin Sayiner, Fatma Genç & Fatma Kandemirli · Journal of Pharmaceutical Research International · 2019

Drug interactions can have desired, reduced or unwanted effects. The probability of interactions increases with the number of drugs taken. Side effects or therapeutic drug interactions can increase or decrease the effects of one or two drugs. Failure may result from clinically me...

Open access Research Article 10.9734/jpri/2019/v26i130128

Removal of Ciprofloxacin from of Pharmaceutical Wastewater by Adsorption on SiO2 Nanoparticle

Ferdos Kord Mostafapour, Davoud Balarak & Marzieh Baniasadi · Journal of Pharmaceutical Research International · 2019

The removal of Ciprofloxacin (CFX) on SiO2 nanoparticle was performed as a function of initial CFX concentration, contact time at fixed pH and adsorbent dose and characterized using scanning electron microscopy (SEM) and Brunauer Emmett Teller (BET) surface area. Amount of CFX up...

Open access Research Article 10.9734/jpri/2018/v25i630127

Evaluation of the Antifungal Activity of Cinnamon, Clove, Thymes, Zataria Multiflora, Cumin and Caraway Essential Oils against Ochratoxigenic Aspergillus ochraceus

Zohreh Abdi Moghadam, Hedayat Hosseini, Zahra Hadian, Bita Asgari, Leila Mirmoghtadaie, Abdorreza Mohammadi, Ehsan Shamloo & Nasrin Haji Seyed Javadi · Journal of Pharmaceutical Research International · 2019

Introduction: Mycotoxin producing fungi are major contributors to food contamination and many epidemics in humans and animals. The adverse effects of the use of chemical preservatives have led to a special focus on the use of natural compounds, especially plant derivatives. The a...

Open access Research Article 10.9734/jpri/2019/v26i130126

In vitro Study Anti-proliferative Potential of Algae Extract against Cancer Cell Line

Morog R. Maddah, Etimad A. Huwait, Abeer Ali Al-Balawi, Said S. Moselhy, Maryam A. ALghamdi, Mustafa A. Zeyadi, Abdulrahman L. AL-Malki & Taha A. Kumosani · Journal of Pharmaceutical Research International · 2019

Background: Oxidative stress is defined as imbalance between oxidant and antioxidant ratio, that lead to oxidative damage of biologically active molecules, finally lead to different disease and initiate carcinogenesis. The drug discovery using natural products as medicinal plants...

Open access Research Article 10.9734/jpri/2019/v26i130124

Determination of Phenolic Contents by HPLC, and Antioxidant, Antimicrobial, Antityrosinase, and Anticholinesterase Activities of Psephellus huber-morathii

Nuriye Korkmaz, Sıla Ozlem Sener, Nuray Balturk, Seyda Kanbolat, Merve Badem, Rezzan Aliyazicioglu, Ufuk Ozgen, Ali Kandemir & Sengul Alpay Karaoglu · Journal of Pharmaceutical Research International · 2019

The goal of our study was to examine of antioxidant, antimicrobial, anticholinesterase activities, and phenolic composition of Psephellus huber-morathii. The antioxidant activities of extracts have been assessed by Ferric reducing antioxidant power (FRAP), cupric reducing antioxi...

Open access Research Article 10.9734/jpri/2019/v26i130125

Comparison and Evaluation of Seven Animal Models of Ischemic Skin Wound: A Review Article

Mohammad Bayat & Sufan Chien · Journal of Pharmaceutical Research International · 2019

Focusing on pathophysiology, prevention, and treatment of ischemic wounds is apriority for medical and basic scientists in order to develop new clinical approaches. However it is not always easy for researchers to choose optimal animal models for their particular assessments. Thi...

Open access Research Article 10.9734/jpri/2018/v25i630119

Salivary Alpha-amylase Activity Level in ST-segment Elevation Myocardial Infarction Patients

Behrang Rezvani Kakhki, Mohsen Salarirad, Seyed Ali Akbar Shamsian, Javad Ramezani, Elnaz Vafadar Moradi, Seyed Mohammad Mousavi & Amir Masoud Hashemian · Journal of Pharmaceutical Research International · 2019

Background and Objective: Sudden death is the main cause of mortality and disability in patients with coronary artery disease or myocardial infarction. The aim of this study was to evaluate the activity level of salivary alpha-amylase to predict malignant ventricular arrhythmias...

Open access Research Article 10.9734/jpri/2018/v25i630120

Error Analysis of Adsorption Isotherm Models for Sulfamethazine onto Multi Walled Carbon Nanotubes

Davoud Balarak & Amir Ali Salari · Journal of Pharmaceutical Research International · 2019

In the present study, Multi walled carbon nanotubes (MWCNTs) was used for the adsorption of Sulfamethazine (SMZ) antibiotics. The adsorbent was characterized by scanning electron microscopy, surface area (BET) and transmission electron microscopy. Batch experiments were carried o...

Open access Research Article 10.9734/jpri/2018/v25i630121

Synthesis of Morphine Loaded Hydroxyapatite Nanoparticles (HAPs) and Determination of Genotoxic Effect for Using Pain Management

Hava Kölemek, İbrahim Bulduk, Yavuz Ergün, Muhsin Konuk, S. Elif Korcan, Recep Liman & Funda Karabağ Çoban · Journal of Pharmaceutical Research International · 2019

Morphine is used as a standard analgesic for intensive pain relief. It relieves acute and chronic pain by acting directly on the central nervous system and to treat myocardial infarction and shortness of breath. However, the use of morphine for the alleviation of chronic pain is...

Open access Research Article 10.9734/jpri/2018/v25i630116

Biological Screening of Traditional Medicinal Plants from Villages of Akkuş (Ordu) in Turkey on the Effects of Tyrosinase

Merve Badem, Nuriye Korkmaz, Sıla Ozlem Sener, Seyda Kanbolat, Ufuk Ozgen, Serhat Sevgi, Rezzan Aliyazicioglu & Maksut Coskun · Journal of Pharmaceutical Research International · 2019

In the present study, ethnomedicinal uses of the plants naturally growing in 35 villages of Akkuş District have been determined. Informations about the uses of the plants have been obtained from villagers using a questionnaire. At the end of the identification of the plants colle...

Open access Research Article 10.9734/jpri/2018/v25i630118

Effect of Anti-Hypertensive Drugs on Blood Pressure Lowering and Renal Function

Olugbenga M. Ajulo, Oluwatoyin H. Ajulo, Blessing W. Anietimfon & Idongesit O. Umoh · Journal of Pharmaceutical Research International · 2019

Aim: Study aimed at evaluating blood pressure (BP) lowering effect of antihypertensive medications and their effect on renal function. Study Design: This was a progressive observational study, evaluating the lowering effect of selected antihypertensive agents on BP and renal func...

Open access Research Article 10.9734/jpri/2018/v25i530111

A Study on Biochemical Properties and Effects of Different Vegetable Oils on Blood Indices in Wistar Rats

Md. Touhidur Rahman, Meherunnahar ., Muhammad Ali, Shaikh Shahinur Rahman, A. Y. K. M. Masud Rana, Kumkum Yeasmin & Md. Hafizur Rahman · Journal of Pharmaceutical Research International · 2019

Mustard oil is popular edible oil in Bangladesh. It contains about more than fifty percent erucic acid which is toxic to human beings. This study evaluated the determination of biochemical properties (acid value, iodine value, saponification value and unsaponifiable matter %) of...

Open access Research Article 10.9734/jpri/2018/v25i530112

Evaluation of Patients’ Responses to Oral Hypoglycemic Agents at a University Health Centre

Olugbenga Matthew Ajulo & Oluwatoyin Hephzibah Ajulo · Journal of Pharmaceutical Research International · 2019

Background: There were 1.5 million deaths caused by diabetes in 2012, of which more than 80% of diabetes deaths occurred in developing countries. WHO estimated diabetes would be the 7th leading cause of death by 2030. Aim: The study aimed at evaluating type 2 diabetes mellitus pa...

Open access Research Article 10.9734/jpri/2018/v25i530113

Association between Demographic Factors and BMI with Osteoporosis: A Cross-Sectional Study in Kurdistan Province, West of Iran

Nasrin Moghimi, Khaled Rahmani & Mohsen Rajabnia · Journal of Pharmaceutical Research International · 2019

Background: Regarding the association of osteoporosis with various fractures and its disabilities, high cost of treatment and rehabilitation, asymptomatic majority of patients and revealing after serious disability and preventable disability and its complications, this study was...

Open access Research Article 10.9734/jpri/2018/v25i530109

The Relationship between Acceptance of Illness and Quality of Life in Mothers with Gestational Diabetes Mellitus

Tahereh Alidoost Balas Baneh, Homa Mosaffay Khomami, Leila Mirhadian & Zahra Atrkarroushan · Journal of Pharmaceutical Research International · 2019

Introduction: Study on quality of life and acceptance of the illness plays a significant role in the health of pregnant women, especially pregnant women with gestational diabetes mellitus. The aim of this study was to determine the relationship between the acceptance of illness a...

Open access Research Article 10.9734/jpri/2018/v25i530110