Background: Moringa oleifera has been used in folk medicine to alleviate several diseases. In the present study, ethanolic extract of Moringa oleifera bark has been investigated to study its potential on paracetamol induced hepatotoxicity on model rats. Methods: Rats (150–200 gm)...
Open access
Research Article10.9734/jpri/2018/v25i430108
The aim of the study is to evaluate the dependence of photo-neutron production on field size, depth in phantom and distance from isocenter and also to calculate the equivalent neutron doses for PTV and OARs of IMRT and 3DCRT techniques using TLD (600/700).The Linac Siemens Oncor...
Open access
Research Article10.9734/jpri/2018/v25i430107
Aim: The study was carried out to determine the anticonvulsant potential of dichloromethane leaf extract of Aspilia africana. Study Design: Three seizure models namely: Pentylenetetrazole (PTZ), strychnine (STC) and maximal electroshock (MES) were used, motor coordination behavio...
Open access
Research Article10.9734/jpri/2018/v25i430106
Background: Phyllanthus fraternus is a tropical plant that has numerous pharmacological activities such as blennorrhagia, colic, diabetes, dysentery, fever, flu, tumours, jaundice, vaginitis, dyspepsia, anti-inflammatory, antioxidant, anticoagulant, anti-diabetic, antiviral and a...
Open access
Research Article10.9734/jpri/2018/v25i430105
Polymyxins are the last line potential antibiotics against multi-drug resistant gram-negative bacteria and consist of two sister antibiotics: Polymyxin B and colistin (polymyxin E). Intravenous use of polymyxins was started from a long ago in the treatment of serious gram-negativ...
Open access
Research Article10.9734/jpri/2018/v25i430104
Objectives: To study the effect of concomitant administering of pomegranate juice orally (PJ) on bioavailability of cyclosporine A (CsA) and independently its potential nephroprotective effect against CsA induced nephrotoxicity. Methods: A- Pharmacokinetic study (PK), Wister rats...
Open access
Research Article10.9734/jpri/2018/v25i330103
Background: Menstrual pain is the most common pain and one of the main causes of referral to a doctor among young women. The aim of this study was to compare the effectiveness of Achillea millefolium (Yarrow) and Matricaria chamomile plants to treat menstrual pain. Methods: This...
Open access
Research Article10.9734/jpri/2018/v25i330101
Background and Aim: Uterine anatomical pathologies play important roles in causing female infertility. This study was conducted to survey the efficiency of hysteroscopy and vaginal sonography in detecting the intrauterine pathologies in infertile women. Methods: This cross-sectio...
Open access
Research Article10.9734/jpri/2018/v25i330102
Objective: Constipation is one of the most common problems of the elderly, causing many complications and high costs for these individuals and affecting their quality of life. This study aimed to compare the effect of Golghand (a pharmaceutical composition of roses and honey) and...
Open access
Research Article10.9734/jpri/2018/v25i330099
Abeer Ali Al-Balawi, Yousri Mohamed Ahmed, Ashwag Albukhari, Shareefa A. ALGhamdi, Mustafa A. Zeyadi, Morog R. Maddah, Etimad H. Huwait, Soad Ali, Taha A. Kumosani & Said S. Moselhy·Journal of Pharmaceutical Research International·2019
Backgound: The generation of oxidative stress can be referred to Aluminium toxic effect in animals and humans. This study aimed to evaluate the role of broccoli (Br) and beetroot (Be) extarcts as antioxidant that prevents oxidative stress that associated with aluminum toxicity. M...
Open access
Research Article10.9734/jpri/2018/v25i330100
Purpose: This study aims to provide a prevalence survey of antibiotic usage and HAIs and evaluate the cost of antibiotic therapy. Methods: All inpatients on surgery, paediatrics, medicine, and ICU specialities were surveyed within a period of one week, April 2016 at Near East Uni...
Open access
Research Article10.9734/jpri/2018/v25i230095
Aims: We performed an initial in vitro study with a single molecule to evaluate the possibility to develop a larger series of hybrid compounds active in Chaga’s disease. Hybridization is an important approach to confer to a single molecule the biological activity of two distinct...
Open access
Research Article10.9734/JPRI/2018/46885
Introduction: The purpose of this study was to investigate whether exhaustion exercise causes endothelial damage and to investigate the effect of ellagic acid on this potential damage. Methods and Materials: The study was carried out on 32 male and adult Spraque - Dawley rats at...
Open access
Research Article10.9734/JPRI/2018/45923
Aims: This work is to develop accurate and simple spectrophotometric methods with the first derivative for estimation of Ibuprofen (IBU), Caffeine (CAF) and Paracetamol (PAR) in bulk and pharmaceutical preparation. Method: The methods use ethanol 90%: 0.1 N sodium hydroxide (25:7...
Open access
Research Article10.9734/JPRI/2018/46503
X-ray is used routinely in many medical procedures for the diagnosis and treatment of diseases. But despite many benefits, there are several complications including breakdown of different bio-molecules, lipids, DNA and proteins that cause cytotoxicity in the body tissue by severa...
Open access
Research Article10.9734/JPRI/2018/46764