Aim: Quinoa has extraordinary and promising nutritional and cultivation features, therefore supplementing or replacing of common cereal grains with quinoa carries high potential benefits to consumers worldwide. Quinoa incorporation in diets can be made more acceptable through ext...
Open access
Research Article10.9734/JPRI/2018/45346
The oral route of administration is associated with some challenges such as poor aqueous solubility and low intestinal permeability of many active pharmaceutical ingredients resulting in decreased drug absorption and subsequent poor bioavailability. In recent years, research on b...
Open access
Research Article10.9734/JPRI/2018/45330
Dissotis thollonii is widely used in Cameroon for the treatment of typhoid fever, gastrointestinal disorders, inflammation, kidney diseases, pregnancy control and sinusitis. However there is lack of experimental data on its possible toxicity. The aim was to investigate acute and...
Open access
Research Article10.9734/JPRI/2018/39412
Objective: The aim of this study was to comprehend the prescribing pattern among cardiovascular patients at the national institute of Cardiovascular Disease (NICVD), Dhaka, Bangladesh. Methodology: The current study was carried out in a national institute of Cardiovascular Diseas...
Open access
Research Article10.9734/JPRI/2018/43122
Seyda Kanbolat, Nuriye Korkmaz, Sıla O. Sener, Merve Badem, Nevin Ulas Colak, Mahmoud Abudayyak, Rezzan Aliyazicioglu, Ufuk Ozgen, Ali Kandemir & Sengul Alpay Karaoglu·Journal of Pharmaceutical Research International·2018
The objective of present study was to specify the antioxidant, antimicrobial, cytotoxic, anticholinesterase, and antityrosinase activities of Verbascum oocarpum Murb., together with its volatile components. The methanolic and aqueous extracts of aerial parts of V. oocarpum indica...
Open access
Research Article10.9734/JPRI/2018/45242
Aims: Wakouba is a salty substance used till medieval ages in traditional medical practices for the preventive treatment of hypertension. The current research focuses on the acute and sub-acute toxicity of this salt using laboratory Wistar rats. Study Design: Wakouba prepared usi...
Open access
Research Article10.9734/JPRI/2018/36463
Aim: This work aims to understand potential inhibitory structural requirements and identify lead compounds for non-small cell lung cancer through 3D-QSAR pharmacophore-based virtual screening, molecular docking, CoMSIA and CoMFA QSAR modelling. Materials and Methods: QSAR pharmac...
Open access
Research Article10.9734/JPRI/2018/44771
Context: The degenerative diseases, due to generation of reactive oxygen species are one of the main human health hazards in the densly populated cities. Objective: This study aims at providinga scientific support related to richness of antioxidants in the marine Ulva lactuca (Ch...
Open access
Research Article10.9734/JPRI/2018/44875
Any drug can have side effect at a certain dose which limits its use. On the other hand, evidence support the role of herbal medicines in the prevention and cure of several diseases. Thymoquinone (TQ) is a bioactive component found in the volatile oil of Nigella sativa "black see...
Open access
Research Article10.9734/JPRI/2018/44944
Background: The aim of this study was to evaluate the synergistic effect of curcumin and Ziziphora extract due to their anti-inflammatory and antioxidant properties on ovarian tissue follicles in the rat model of the polycystic ovary syndrome (PCOS). Methods: This experimental st...
Open access
Research Article10.9734/JPRI/2018/45124
Aims: The current research has shown that the complications of hypertensive diabetes have a great impact on the body. Telmisartan, an angiotensin II antagonist, has the dual role of antihypertensive and antidiabetics effects. This research aims to find a novel compound to treat h...
Open access
Research Article10.9734/JPRI/2018/43482
Objective: Traditionally Ficus hispida is used as a palliative for pain, inflammation, diabetes, fever and neurological disorders. The present study set out to evaluate the antinociceptive, anti-pyretic and anti-inflammatory activity of the methanolic extract of Ficus hispida lea...
Open access
Research Article10.9734/JPRI/2018/41664
Background and Objective: Numerous monoterpenes are present in the essential oil of Sautreja khuzistanica Jamzad. In this study, the effect of methyl jasmonate (MJ) applied in the LS medium of shoot cultures of S. khuzistanica on individual monoterpene percentages were evaluated....
Open access
Research Article10.9734/JPRI/2018/43472
M. Z. Urbán-Morlán, S. E. Mendoza-Elvira, A. Jiménez-García de León, H. Ramírez-Mendoza, N. Mendoza-Muñoz, A. Ciprián-Carrasco & D. Quintanar-Guerrero·Journal of Pharmaceutical Research International·2018
Aims: To study the effect of glycyrrhizinic acid (GA) solutions on uninfected and PRRS (Porcine Reproductive and Respiratory Syndrome) virus-infected cells in culture. An attempt of testing loaded nanoparticles with GA on cells was also explored. Study Design: Different concentra...
Open access
Research Article10.9734/JPRI/2018/44806
Background and Objective: Adhesion is an important complication of abdominal and pelvic surgery. Applying corticosteroids reduces vascular permeability and releasing of cytokines and chemotactic factors. The current study has examined the effect of clobetasol solution on intra-ab...
Open access
Research Article10.9734/JPRI/2018/45122