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All published articles 7450

Investigating the Elements of Parent-Child Relationship and Parental Satisfaction among Mothers with Breast Cancer without Breast Cancer and Comparing Them with Each Other

Fatemeh Merati Fashi & Fatemeh Ghiasi · Journal of Pharmaceutical Research International · 2018

The purpose of this study was to investigate the elements of parent parent communication patterns and parental role satisfaction among mothers with breast cancer and non-breast cancer and compare them with each other. 60 women with breast cancer and 60 women without breast cancer...

Open access Research Article 10.9734/JPRI/2018/43007

Portulaca oleracea Reduces Lipemia, Glycemia, and Oxidative Stress in Streptozotocin-induced Diabetic Rats Fed Cholesterol-enriched Dietq

F. Djellouli, D. Krouf, M. A. Lacaille-Dubois & M. Bouchenak · Journal of Pharmaceutical Research International · 2018

Aims: In this study, the effects of Portulaca oleracea (Po) in the treatment of hypercholesterolemia combined with diabetes in rats were investigated. Place and Duration of Study: Laboratory of Clinical and Metabolic Nutrition, Department of Biology, Nature and Life Sciences Facu...

Open access Research Article 10.9734/JPRI/2018/43495

Chimeric Antigen Receptor T Cell (CAR – T) Therapy – A Novel Treatment in Cancer

Priyadarsini Baskaran, Venkatraman Karthikeayan & Anusha Natarajan · Journal of Pharmaceutical Research International · 2018

Cancer is one of the most challenging diseases affecting mankind. It continues to defy all the treatment modalities and advancements and claims millions of lives every year. Chimeric Antigen Receptor –T (CAR-T) cell therapy is one of the breakthroughs in cancer treatment. Chimeri...

Open access Research Article 10.9734/JPRI/2018/43471

Reproductive Effects of Hydromethanolic Leaf Extracts of Cnidoscolus aconitifolius (Euphorbiacea) in Streptozotocin Induced-diabetic Rats

Weleh, Ikechukwu Iyke, I. Green, Kinikanwo, Njoku, Bestman & Oriji, Vadunume Kingsley · Journal of Pharmaceutical Research International · 2018

Introduction: The potency of plants is largely due to the presence of phytochemicals contain in them. Plant-derived chemicals influence endocrine activities in animals and humans have received affluent attention due to their possible adverse effects or benefits, especially on sex...

Open access Research Article 10.9734/JPRI/2018/35367

Mechanism of Anticonvulsant Effects of Ethanol Leaf Extract and Fractions of Milicia excelsa (Moraceae) in Mice

Lateef Abiola Akinpelu, Moses Atanda Akanmu & Efere Martins Obuotor · Journal of Pharmaceutical Research International · 2018

Aims: This study investigated the anticonvulsant potential of ethanol leaf extract and fractions of Milicia excelsa (Moraceae). Study Design: This study used experimental animal models predictive of human convulsion in mice. Place and Duration of Study: Department of Pharmacology...

Open access Research Article 10.9734/JPRI/2018/42430

Volatile Constituents, Antimicrobial and Antioxidant Activities of the Aerial Parts of Origanum majorana L. from Yemen

Mohamed Al-Fatimi · Journal of Pharmaceutical Research International · 2018

Aims: There is no report about the analysis of volatile composition of Origanum majorana L. (Lamiaceae) by static headspace method in combination with GC-MS. The present study reports for the first time the volatile composition, antimicrobial and antioxidant activities of O. majo...

Open access Research Article 10.9734/JPRI/2018/35932

Microbiological Evaluation and Antibiotic Susceptibility Patterns of Organisms Isolated from Frozen Chicken Products Sold in Port Harcourt, Nigeria

Catheirine N. Stanley & Victoria O. Arueyingho · Journal of Pharmaceutical Research International · 2018

Frozen chicken products contribute a large proportion of the protein needs of the average Nigerian family. Although chicken products are safe when frozen continuously and properly stored, they are easily prone to microbial contamination. However, the majority of the frozen chicke...

Open access Research Article 10.9734/JPRI/2018/41616

Physiology of Speech/Voice Production

Imen Daly, Zied Hajaiej & Ali Gharsallah · Journal of Pharmaceutical Research International · 2018

Aims: This study looks at the pathological disorders analysis from speech signals. She presents the effectiveness of the few parameters of the glottal source and these moments of closure for the diagnosis of the Parkinson’s disease. Study Design: This analysis is performed around...

Open access Research Article 10.9734/JPRI/2018/42403

Routine Replacement or Clinically Indicated Replacement of Peripheral Intravenous Catheters

Sarah Amouei Foumani, Ezzat Paryad, Atefeh Ghanbari Khanghah & Ehsan Kazemnezhad Leili · Journal of Pharmaceutical Research International · 2018

Introduction: Intravenous catheter replacement time is still one of the challenges before care systems. Replacement of the catheter after 72 hours is now implemented in many treatment centers. Aim: The aim of this study was to determine the complications of peripheral intravenous...

Open access Research Article 10.9734/JPRI/2018/38767

QTc Prolongation and Arrhythmia Development in the Treatment of ICU Delirium: An Investigation of Medication-Related Risk Factors

Anli Francis, Daniel S. Eiferman, J. Michael Boyd, Gary Phillips & Claire V. Murphy · Journal of Pharmaceutical Research International · 2018

Aims: Antipsychotics are commonly used for ICU delirium, although there is limited data describing the risk of QTc prolongation with these therapies. This study aimed to evaluate the prevalence of and risk factors for QTc prolongation associated with antipsychotic agents for ICU...

Open access Research Article 10.9734/JPRI/2018/42942

Formulation and Evaluation of a Syrup Based on Balanites aegyptiaca L. Delile

Ouédraogo Salfo, Traoré Sidiki, Yoda Jules, Traoré Aristide, Traoré Tata Kadiatou, Lompo Marius, Kini Felix & Ouédraogo Sylvin · Journal of Pharmaceutical Research International · 2018

Introduction: The kernel powder of the fruit of Balanites aegyptiaca (L.) Del is mixed with sorghum flour for the treatment of intestinal worms in Burkina Faso. Previous preclinical studies have demonstrated the efficacy and safety of the medicine. Objective: The objective of thi...

Open access Research Article 10.9734/JPRI/2018/42857

Development and Characterization of Self-Nano Emulsifying Drug Delivery System of Ibuprofen

Z. S. Yahaya, A. R. Oyi, T. S. Allagh & A. Abdulsamad · Journal of Pharmaceutical Research International · 2018

Aim: This work aimed to formulate self-nano emulsifying drug delivery systems (SNEDDS) for augmenting the biopharmaceutical performance of ibuprofen, a poorly-water soluble drug and subsequently evaluate its anti-inflammatory activity. Methodology: Pseudoternary phase diagram stu...

Open access Research Article 10.9734/JPRI/2018/43090

Qualitative Determination of the Secondary Metabolites and Evaluation of the Antimicrobial Activity of Leaf Extracts from Different Plant Families (Boraginaceae, Fabaceae, Lamiaceae and Lauraceae) against Microorganisms of Clinical Importance

Ruby A. Ynalvez, Kassandra L. Compean & Alfred Addo-Mensah · Journal of Pharmaceutical Research International · 2018

Aims: This study was conducted to investigate the antimicrobial activities of Sassafras albidum (Nutt.), Ehretia anacua (Terán & Berl.), Melissa officinalis (Linn.), Eysenhardtia texana (Scheele), and Melissa odorata. Specifically, this study aims to evaluate the antimicrobia...

Open access Research Article 10.9734/JPRI/2018/41205

Nonlinear Isotherms and Kinetics and Application Error Functions for Adsorption of Tetracycline on Lemna Minor

Davoud Balarak, Ferdos Kord Mostafapour & Aram Dokht Khatibi · Journal of Pharmaceutical Research International · 2018

In this study, removal of Tetracycline (TC) antibiotics from artificially contaminated water has been investigated with the aim of detoxifying pharmaceutical wastewater before their safe disposal onto land or into river waters. The adsorption of TC occurred by studying the effect...

Open access Research Article 10.9734/JPRI/2018/42583

Repeated Exposure of Herbal Concoction Imprints Toxicological Implications through Redox Imbalance in Male Wistar Rats

J. O. Fatoki, J. A. Badmus, O. T. Adedosu, A. A. Adegoke, O. R. Lawal, I. A. Ogunmola & T. M. Omotayo · Journal of Pharmaceutical Research International · 2018

Aim: A Large percentage of the Nigerian populace consumes herb concoction prepared by local vendors without due regard to quality control such as toxicity and validity testing. The present study assessed the toxicological effects of continuous intake of some locally prepare herbs...

Open access Research Article 10.9734/JPRI/2018/42002