In the last years, the transport and release mechanism of bioactive compounds has been studied. The liposomes are multivesicular systems that enhance the absorption, stability, and transport of these compounds. The glucosamine is an amino-monosaccharide, it has been associated wi...
Open access
Research Article10.9734/JPRI/2018/39746
Background: Atorvastatin, a commonly prescribed drug for the management of hyperlipidemia, acts as competitive inhibitors of HMG-CoA reductase—a rate-limiting enzyme in cholesterol synthesis. On the other hand, riboflavin is also a well-studied micronutrient known for its anti-pr...
Open access
Research Article10.9734/JPRI/2018/39652
Statins and thiazides which are widely prescribed for the treatment of hyperlipidemia and hypertension play an important role in bone metabolism and may have potential therapeutic implications for osteoporosis. Moreover, concomitant use of statins and thiazides may offer additiv...
Open access
Research Article10.9734/JPRI/2018/40943
Aims: To carry out phytochemical screening, acute toxicity test and to investigate the hypoglycemic potential of the ethanol extract and fractions of Globimetula braunii leaves. Place and Duration of Study: Department of Pharmacognosy and Drug Development and Animal House, Depart...
Open access
Research Article10.9734/JPRI/2018/39870
African bush Pear known as is a well-known plant in West Africa, the fruits are edible while the bark, leaves, stem and roots are employed for a variety of purposes. It has been previously reported to possess high antioxidant properties and has also been used in folkloric medicin...
Open access
Research Article10.9734/JPRI/2018/36166
The antiproliferative effects of the methanol leaf extracts of Vernonia amygdalina (V. amygdalina) Del (Asteraceae) on Vascular Smooth Muscle Cells (VSMC) and Human Colorectal Adenocarcinoma Cell line (HT 29) were investigated using the Cell Titer 96 MTT Proliferation Assay where...
Open access
Research Article10.9734/JPRI/2018/39496
Background: Cancer is the second most dreadful disease of the globe and nearly 100 different types of cancer have been identified. The main problem with the cancer is its resistance and many existed synthetic molecules are becoming clinically insignificant on exposure to cancer c...
Open access
Research Article10.9734/JPRI/2018/40529
Polyhydroxyalkanoates (PHAs), which is produced by several bacteria, is a biodegradable polymer that has many industrial and medical applications such as heart valves, scaffold, suture and drug delivery. The aim of the present study is to isolate and identify the bacteria produci...
Open access
Research Article10.9734/JPRI/2018/39532
Aims: To critically review the potential side effects relating to pain and dehydration symptoms from the top 20 selling pharmaceuticals. Methodology: The Physicians’ Desk Reference medication guide and drugs.com website was used to review medication side effects. The categories o...
Open access
Research Article10.9734/JPRI/2018/39544
In continuation of our previous research, more than 60 microbial strains that were isolated from soil samples collected from desert, farming and mineral regions of Iran and sixteen isolated strains that produced antimicrobial metabolites were found to be effective against Escheri...
Open access
Research Article10.9734/JPRI/2018/39144
Introduction: Cervical cancer is the fourth most common neoplasm among women worldwide, with the majority of cases occurring in developing countries. High-risk human papilloma viruses (HPVs) types are accounted for more than 90% of cervical carcinomas. Despite standard treatment...
Open access
Research Article10.9734/JPRI/2018/34725
Objective: Many plants used in traditional medicine still need to be studied scientifically in order to verify their medical usefulness and standardize their pharmaceutical properties. The present study aimed at evaluating the antihyperglycemic activity of aqueous and alcoholic e...
Open access
Research Article10.9734/JPRI/2018/40667
Khadijah S. Balamash, Said S. Moselhy, Jehan A. Khan, Etimad H. Huwait, Nawal Helmi, Khalid O. Abulnaja, Widad M. Al-Bishri, Abdulrahman L. AL-Malki, Taha A. Kumosani & Soonham S. Yaghmoor·Journal of Pharmaceutical Research International·2018
Background: Nowadays, alternative medicinal therapy is recommended for protection and management liver diseases. Cinnamon is popular flavoring ingredient, widely used in as additive worldwide. Objective: The mechanism of hepato-protective activity of water (WE) or ethanolic extra...
Open access
Research Article10.9734/JPRI/2018/40272
From ancient times, herbal medicines are in use to cure the diseases due to their potential and less side effects. But difficulties in identification, processing, standardizing, extracting of herbal drugs, it rarely attracts scientists towards the development of novel delivery sy...
Open access
Research Article10.9734/JPRI/2018/39143
Aim: Drug combination studies are of keen interest, especially to the clinician who encounters patients with multiple disease symptoms. In our study, we tried to assess the toxic/beneficial effect of a prominent calcium channel blocker–Amlodipine, when administered with Levocetir...
Open access
Research Article10.9734/JPRI/2018/39268