Skip to content

All published articles 7450

Effects of Medicinal Plants on Nocturia: A Systematic Review

Mahnaz Yavangi, Ramazan Khodadadi-Arpanahi & Saeid Heidari-Soureshjani · Journal of Pharmaceutical Research International · 2018

Nocturia is one of the common disorders that are associated with certain complications such as fracture and declined quality of life in addition to disrupting sleep. We, therefore, sought to review the evidence on the effects and action mechanisms of medicinal plants on nocturia....

Open access Research Article 10.9734/JPRI/2018/40251

Use of In vitro Dissolution Testing to Assess Multiple Generic Metformin Tablets

Sze S. Wong & Suong N. T. Ngo · Journal of Pharmaceutical Research International · 2018

Aims: Metformin is a high-solubility and low-permeability drug that is widely used as an oral anti-diabetic medication. In many countries, metformin is available as multiple generic formulations, with over 10 registered products, which are approved to be dispensed interchangeable...

Open access Research Article 10.9734/JPRI/2018/39508

Effects of Resveratrol on Oxidative DNA Damage Induced by the Acute Swimming Exercise

Funda Karabağ Çoban, Mustafa Akil, Recep Liman & Ibrahim Ciğerci · Journal of Pharmaceutical Research International · 2018

Background: The point of this study was to look at how resveratrol administration affects on intense swimming exercise in oxidative circumstance. The investigation may suggest the administration of resveratrol supplements for athletes who are practice intensely. Methods: In this...

Open access Research Article 10.9734/JPRI/2018/39347

Studies of Heavy Metal Contents and Microbial Profile in Selected Pediatric Oral Liquid Preparations Available in Bangladesh

Md. Monir Hossain, Shamsun Nahar, Tasrina Rabia Choudhury, Masum Shahriar, Nizam Uddin, A. F. M. Mahmudul Islam, Arjyabrata Sarker & Pijus Saha · Journal of Pharmaceutical Research International · 2018

Thirty different Pharmaceutical, Complementary and Alternative Medicine (CAM) products were tested for heavy metal contents and microbiological profile using standard methods. Among the investigated eleven heavy metals, seven (Cr, Co, Cu, Mn, Fe, Ni and Zn) were in detectable lev...

Open access Research Article 10.9734/JPRI/2018/39497

Determination of Sodium (2-(2, 6-dichloroanilino) phenyl) Acetic Acid in Human Plasma by Rapid and Sensitive HPLC Method and UV-Spectrophotometry: Its Comparative Evaluation

Saeed-Ul-Hassan ., Javaria Chishti, Kashif Barkat, Hammad Yousaf & Asif Mahmood · Journal of Pharmaceutical Research International · 2018

Aim: The objectives of current study were to develop and validate a simple, rapid, and sensitive HPLC method for determination of sodium (2-(2, 6- dichloroanilino) phenyl) acetic acid (SDPAA) in human plasma according to US-FDA guidelines and determination of SDPAA by UV- Spectro...

Open access Research Article 10.9734/JPRI/2018/39301

The Effect of Ethanol Extract of Xylopia aethiopica Fruits on the Histomorphology of the Kidney of Albino Wistar Rats

I. U. Umoh & A. U. Ekanem · Journal of Pharmaceutical Research International · 2018

Aims: The study investigated the effect of ethanol extract of Xylopia aethiopica fruits on the histomorphology of the kidney of albino Wistar rats. Study Design:  Twenty (20) albino Wistar rats weighing between 130 – 180 g were assigned into four (4) groups of five rats each. Gro...

Open access Research Article 10.9734/JPRI/2018/39356

Advances in Research Progress of H. pylori

Fawad Ahmed, Jawad Ahmed, Hammad Ahmed, Syed Saeed Ul Hassan, Javed Iqbal & Ali Sharif · Journal of Pharmaceutical Research International · 2018

Helicobacter pylori infection is a global public health problem. It can lead to chronic gastritis, stomach & duodenal ulcer, mucosa-associated lymphoid tissue lymphoma and gastric adenocarcinoma. Globally a lot of research has been conducted on H. pylori. This review is focus...

Open access Research Article 10.9734/JPRI/2018/39597

Comparison of the Efficacy of Different Hydrocortisone-Induced Cataract Models in Developing Chick Embryos

Reşat Duman, Tolga Ertekin, Rahmi Duman, Ayhan Vurmaz, Tülay Köken & Abdülkadir Bilir · Journal of Pharmaceutical Research International · 2018

Aim: To evaluate and compare the efficacy of different hydrocortisone-induced cataract models in chick embryos. Material and methods: On the 15th day of the study, hydrocortisone succinate sodium (HC) (0.5 μmol/egg or 0.25 μmol/egg) was administered directly into the air sac (AS)...

Open access Research Article 10.9734/JPRI/2018/39888

Effect of β-cyclodextrin and Hydroxypropyl β-cyclodextrin on Aqueous Stability, Solubility and Dissolution of Novel Anti-cancer Drug Rigosertib

Hardikkumar H. Patel, Maitri Trivedi, Manoj Maniar, Chen Ren & Rutesh H. Dave · Journal of Pharmaceutical Research International · 2018

Aim: To study Effect of β-cyclodextrin and hydroxypropyl β-cyclodextrin on aqueous stability, solubility and dissolution of novel anti-cancer drug Rigosertib. Methods: β-cyclodextrin and hydroxypropyl β-cyclodextrin were used to form complex with Rigosertib. The effect of cyclode...

Open access Research Article 10.9734/JPRI/2018/39890

Phytochemical Screening, Antioxidant Activities and Antibacterial Potential of Leaf Extracts of Buchanania axillaris L.

M. Vidya Vani, S. Anjum Mobeen & K. Riazunnisa · Journal of Pharmaceutical Research International · 2018

Aim: Buchanania axillaris L. (B. axillaris) is a traditional medicinal plant distributed in India and other Asian countries. It is well known as ‘Cuddapah Almond’ and belongs to the family of Anacardiaceae. The aim of the present study was to determine the phytochemicals present,...

Open access Research Article 10.9734/JPRI/2018/39120

North Cyprus Pharmacist’s Cognition and Practice of Pharmaceutical Care

Abdikarim Mohamed Abdi, Abdullah T. Zarouri, Louai Saloumi & Bilgen Basgut · Journal of Pharmaceutical Research International · 2018

The aim of this project is to assess community pharmacists’ attitudes towards their professional practice and to determine their perceived competence in various pharmaceutical activities. The philosophy of Pharmaceutical care focuses on the responsibility of pharmacist to meet al...

Open access Research Article 10.9734/JPRI/2018/39051

Glycemic Index Profiling of Quinoa (Chenopodium quinoa Willd) Variety

M. Priyanka, W. Jessie Suneetha, K. Uma Maheswari, K. B. Suneetha & B. Anila Kumari · Journal of Pharmaceutical Research International · 2018

Quinoa has proteins of high biological value, carbohydrates of low glycemic index and phytosteroids with w - 3 and 6 fatty acids that provide health benefits. The main advantage of quinoa is that along with being a protein supplement in the flour industry, it meets the increasing...

Open access Research Article 10.9734/JPRI/2018/37915

Escobar Syndrome: Difficulties in Anesthesia Management

Arzu Karaveli, Ülkü Kum, Deniz Yüksel, Erhan Özyurt, Bilge Karsli, Kerem Inanoğlu & Sadık Özmen · Journal of Pharmaceutical Research International · 2018

Introduction: Escobar syndrome (multiple pterygium coli) is a rare autosomal recessive disorder which characterized by various malformations. Regarding anaesthesia management, these patients should be considered due to difficult mask ventilation and intubation and risk of maligna...

Open access Research Article 10.9734/JPRI/2018/38935

Cytotoxic and Anticancer Activities of Indoline-2,3-dione (Isatin) and Its Derivatives

Sulayman A. Ibrahim & Tilal Elsaman · Journal of Pharmaceutical Research International · 2018

Isatin (1H-indolin-2,3-dione) is a versatile bioactive and heterocyclic scaffold with an indole nucleus. For the past decades, isatin and its derivatives have shown tremendous interest among researchers (organic and medicinal chemists). Hence, their extensive structural modificat...

Open access Research Article 10.9734/JPRI/2018/39708

Improvement of Secondary Metabolites from Phyllanthus odontadenius against Malaria by Mutagenesis

Sébastien Luyindula Ndiku, Rufin Kikakedimau Nakweti, Véronique Sinou, Florent Rouvier, Théophile Mbemba Fundu, Claudine Franche & Richard Cimanga Kanianga · Journal of Pharmaceutical Research International · 2018

Aims: Majority of deaths in children aged under 5 years are due to Plasmodium falciparum malaria. Malaria deaths in children decreased but malaria remains a major killer of children, taking the life of a child every 2 minutes. This study aims to investigate the increasing of the...

Open access Research Article 10.9734/JPRI/2018/37978